Patents by Inventor Iain Johnson
Iain Johnson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20170073359Abstract: The present invention relates to compounds that are substrates for an enzyme, and upon reaction with the enzyme provide a detectable response, such as an optically detectable response. In particular, the compounds have utility in detecting the presence of a ?-lactamase in a sample. In addition to the compounds, methods are disclosed for analyzing a sample for the presence of a ?-lactmase, for example, as an indicator of expression of a nucleic acid sequence including a sequence coding for a ?-lactmase. Kits are disclosed that include the disclosed compounds and additional components, for example, cells, antibodies, a ?-lactmase or instructions for using the components in an assay.Type: ApplicationFiled: September 26, 2016Publication date: March 16, 2017Inventors: Schuyler CORRY, William DOWNEY, Brian FILANOSKI, Kyle GEE, Lawrence GREENFIELD, James HIRSCH, Iain JOHNSON, Aleksey RUKAVISHNIKOV
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Publication number: 20170037248Abstract: The invention provides novel fluorinated resorufin compounds that are of use in a variety of assay formats. Also provided are methods of using the compounds and kits that include a compound of the invention and instructions detailing the use of the compound in one or more assay formats.Type: ApplicationFiled: October 21, 2016Publication date: February 9, 2017Inventors: Robert Batchelor, Yue GE, Iain JOHNSON, Wai-Yee LEUNG, Jixiang LIU, Brian PATCH, Peter SMALLEY, Thomas STEINBERG, Kyle GEE
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Publication number: 20160334393Abstract: Fluorescent quinolizinocoumarin compounds substituted with electrophilic reactive groups that bind thiol compounds are described. The compounds are useful in detecting oxidative stress and processes associated therewith in live cells.Type: ApplicationFiled: July 27, 2016Publication date: November 17, 2016Inventors: Kyle GEE, Michael JANES, Iain JOHNSON, Hee Chol KANG
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Publication number: 20160139135Abstract: The present invention relates to compounds that are substrates for an enzyme, and upon reaction with the enzyme provide a detectable response, such as an optically detectable response. In particular, the compounds have utility in detecting the presence of a ?-lactamase in a sample. In addition to the compounds, methods are disclosed for analyzing a sample for the presence of a ?-lactmase, for example, as an indicator of expression of a nucleic acid sequence including a sequence coding for a ?-lactmase. Kits are disclosed that include the disclosed compounds and additional components, for example, cells, antibodies, a ?-lactmase or instructions for using the components in an assay.Type: ApplicationFiled: September 11, 2014Publication date: May 19, 2016Inventors: Schuyler CORRY, William Downey, Brian Filanoski, Kyle Gee, Lawrence Greenfield, James Hirsch, Iain Johnson, Aleksey Rukavishnikov
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Patent number: 9212385Abstract: The invention provides novel fluorinated resorufin compounds that are of use in a variety of assay formats. Also provided are methods of using the compounds and kits that include a compound of the invention and instructions detailing the use of the compound in one or more assay formats.Type: GrantFiled: September 12, 2012Date of Patent: December 15, 2015Assignee: Life Technologies CorporationInventors: Robert H. Batchelor, Yue Ge, Iain Johnson, Wai-Yee Leung, Jixiang Liu, Brian Patch, Peter Smalley, Thomas Steinberg, Kyle Gee
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Publication number: 20150219634Abstract: Fluorescent quinolizinocoumarin compounds substituted with electrophilic reactive groups that bind thiol compounds are described. The compounds are useful in detecting oxidative stress and processes associated therewith in live cells.Type: ApplicationFiled: February 6, 2015Publication date: August 6, 2015Inventors: Kyle GEE, Michael Janes, Iain Johnson, Hee Chol Kang
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Patent number: 8981100Abstract: Fluorescent quinolizinocoumarin compounds substituted with electrophilic reactive groups that bind thiol compounds are described. The compounds are useful in detecting oxidative stress and processes associated therewith in live cells.Type: GrantFiled: July 24, 2008Date of Patent: March 17, 2015Assignee: Life Technologies CorporationInventors: Hee Chol Kang, Kyle Gee, Iain Johnson, Michael Janes
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Patent number: 8865891Abstract: The present invention relates to compounds that are substrates for an enzyme, and upon reaction with the enzyme provide a detectable response, such as an optically detectable response. In particular, the compounds have utility in detecting the presence of a ?-lactamase in a sample. In addition to the compounds, methods are disclosed for analyzing a sample for the presence of a ?-lactamase, for example, as an indicator of expression of a nucleic acid sequence including a sequence coding for a ?-lactamase. Kits are disclosed that include the disclosed compounds and additional components, for example, cells, antibodies, a ?-lactamase or instructions for using the components in an assay.Type: GrantFiled: September 13, 2012Date of Patent: October 21, 2014Assignee: Life Technologies CorporationInventors: Schuyler Corry, William Downey, Brian Filanoski, Kyle Gee, Lawrence Greenfield, James Hirsch, Iain Johnson, Aleksey Rukavishnikov
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Publication number: 20140220612Abstract: The invention provides novel fluorinated resorufin compounds that are of use in a variety of assay formats. Also provided are methods of using the compounds and kits that include a compound of the invention and instructions detailing the use of the compound in one or more assay formats.Type: ApplicationFiled: April 8, 2014Publication date: August 7, 2014Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Robert BATCHELOR, Yue GE, Iain JOHNSON, Wai-Yee LEUNG, Jixiang LIU, Brian PATCH, Peter SMALLEY, Thomas STEINBERG, Kyle GEE
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Patent number: 8568220Abstract: A method of determining liability for a plurality of multiples bets placed via a computerised betting system, each multiples bet comprising a single transaction on a plurality of outcomes selected from a group of possible transactions, the method comprising selecting a most popular transaction from the group, evaluating all other transactions within the group on the basis that the most popular transaction is a winning transaction to produce a first result, evaluating all other transactions within the group on the basis that the most popular transaction is not a winning transaction to produce a second result and selecting one of the first and second results that indicates the worst case liability.Type: GrantFiled: January 18, 2008Date of Patent: October 29, 2013Assignee: The Sporting Exchange Ltd.Inventors: Iain Johnson Andersen, Matthew James Searle, David Glen Jeffery, Steven John High
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Publication number: 20130090470Abstract: The present invention relates to compounds that are substrates for an enzyme, and upon reaction with the enzyme provide a detectable response, such as an optically detectable response. In particular, the compounds have utility in detecting the presence of a ?-lactamase in a sample. In addition to the compounds, methods are disclosed for analyzing a sample for the presence of a ?-lactmase, for example, as an indicator of expression of a nucleic acid sequence including a sequence coding for a ?-lactmase. Kits are disclosed that include the disclosed compounds and additional components, for example, cells, antibodies, a ?-lactmase or instructions for using the components in an assay.Type: ApplicationFiled: September 13, 2012Publication date: April 11, 2013Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Schuyler CORRY, William Downey, Brian Filanoski, Kyle Gee, Lawrence Greenfield, James Hirsch, Iain Johnson, Aleksey Rukavishnikov
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Patent number: 8318450Abstract: The present invention relates to compounds that are substrates for an enzyme, and upon reaction with the enzyme provide a detectable response, such as an optically detectable response. In particular, the compounds have utility in detecting the presence of a ?-lactamase in a sample. In addition to the compounds, methods are disclosed for analyzing a sample for the presence of a ?-lactmase, for example, as an indicator of expression of a nucleic acid sequence including a sequence coding for a ?-lactmase. Kits are disclosed that include the disclosed compounds and additional components, for example, cells, antibodies, a ?-lactmase or instructions for using the components in an assay.Type: GrantFiled: June 22, 2011Date of Patent: November 27, 2012Assignee: Life Technologies CorporationInventors: Schuyler Corry, William Downey, Brian Filanoski, Kyle Gee, Lawrence Greenfield, James Hirsch, Iain Johnson, Aleksey Rukavishnikov
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Patent number: 8173698Abstract: The present invention provides fluorogenic probes and corresponding fluorescent compounds, methods of using the probes, compounds and kits that include the probes.Type: GrantFiled: February 29, 2008Date of Patent: May 8, 2012Assignee: Life Technologies CorporationInventors: Iain Johnson, Jixiang Liu, Brian Patch, Wai-Yee Leung
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Publication number: 20120040380Abstract: The present invention relates to compounds that are substrates for an enzyme, and upon reaction with the enzyme provide a detectable response, such as an optically detectable response. In particular, the compounds have utility in detecting the presence of a ?-lactamase in a sample. In addition to the compounds, methods are disclosed for analyzing a sample for the presence of a ?-lactmase, for example, as an indicator of expression of a nucleic acid sequence including a sequence coding for a ?-lactmase. Kits are disclosed that include the disclosed compounds and additional components, for example, cells, antibodies, a ?-lactmase or instructions for using the components in an assay.Type: ApplicationFiled: June 22, 2011Publication date: February 16, 2012Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: SCHUYLER BOON CORRY, WILLIAM LOUIS DOWNEY, BRIAN FILANOSKI, KYLE RICHARD GEE, I. LAWRENCE GREENFIELD, JAMES DAVID HIRSCH, IAIN JOHNSON, ALEKSEY RUKAVISHNIKOV
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Publication number: 20110086341Abstract: The invention provides novel fluorinated resorufin compounds that are of use in a variety of assay formats. Also provided are methods of using the compounds and kits that include a compound of the invention and instructions detailing the use of the compound in one or more assay formats.Type: ApplicationFiled: December 17, 2010Publication date: April 14, 2011Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Robert Batchelor, Yue Ge, Iain Johnson, Wai-Yee Leung, Jixiang Liu, Brian Patch, Peter Smalley, Thomas Steinberg, Kyle Gee
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Publication number: 20110045503Abstract: Fluorescent quinolizinocoumarin compounds substituted with electrophilic reactive groups that bind thiol compounds are described. The compounds are useful in detecting oxidative stress and processes associated therewith in live cells.Type: ApplicationFiled: July 24, 2008Publication date: February 24, 2011Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Kyle Gee, Michael Janes, Iain Johnson, Hee Chol Kang
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Patent number: 7875261Abstract: The invention provides novel fluorinated resorufin compounds that are of use in a variety of assay formats. Also provided are methods of using the compounds and kits that include a compound of the invention and instructions detailing the use of the compound in one or more assay formats.Type: GrantFiled: January 16, 2008Date of Patent: January 25, 2011Assignee: Life Technologies CorporationInventors: Robert Batchelor, Yue Ge, Iain Johnson, Wai-Yee Leung, Jixiang Liu, Brian Patch, Peter Smalley, Thomas Steinberg, Kyle Gee
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Publication number: 20100093430Abstract: A method of determining liability for a plurality of multiples bets placed via a computerised betting system, each multiples bet comprising a single transaction on a plurality of outcomes selected from a group of possible transactions, the method comprising selecting a most popular transaction from the group, evaluating all other transactions within the group on the basis that the most popular transaction is a winning transaction to produce a first result, evaluating all other transactions within the group on the basis that the most popular transaction is not a winning transaction to produce a second result and selecting one of the first and second results that indicates the worst case liability.Type: ApplicationFiled: January 18, 2008Publication date: April 15, 2010Applicant: THE SPORTING EXCHANGE LTD.Inventors: Iain Johnson Andersen, Matthew James Searle, David Glen Jeffery, Steven John High
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Publication number: 20090047692Abstract: The present invention relates to compounds that are substrates for an enzyme, and upon reaction with the enzyme provide a detectable response, such as an optically detectable response. In particular, the compounds have utility in detecting the presence of a ?-lactamase in a sample. In addition to the compounds, methods are disclosed for analyzing a sample for the presence of a ?-lactmase, for example, as an indicator of expression of a nucleic acid sequence including a sequence coding for a ?-lactmase. Kits are disclosed that include the disclosed compounds and additional components, for example, cells, antibodies, a ?-lactmase or instructions for using the components in an assay.Type: ApplicationFiled: April 7, 2008Publication date: February 19, 2009Applicant: INVITROGEN CORPORATIONInventors: Schuyler Boon CORRY, William Louis Downey, Brian Filanoski, Kyle Richard Gee, I. Lawrence Greenfield, James David Hirsch, Iain Johnson, Aleksey Rukavishnikov
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Publication number: 20080160627Abstract: The present invention provides fluorogenic probes and corresponding fluorescent compounds, methods of using the probes, compounds and kits that include the probes.Type: ApplicationFiled: February 29, 2008Publication date: July 3, 2008Applicant: INVITROGEN CORPORATIONInventors: Iain JOHNSON, Wai-Yee Leung, Jixiang Liu, Brian Richard Patch