Abstract: A method of joining at least two parts includes steps of dispersing a joining material comprising a multi-phase nanocrystalline magnetic metal-aluminum powder at an interface between the at least two parts to be joined and applying an alternating magnetic field (AMF). The AMF has a magnetic field strength and frequency suitable for inducing magnetic hysteresis losses in the metal-aluminum powder and is applied for a period that raises temperature of the metal-aluminum powder to an exothermic transformation temperature. At the exothermic transformation temperature, the metal-aluminum powder melts and resolidifies as a metal aluminide solid having a non-magnetic configuration.

Abstract: Nanostructured Mn—Al, Mn—Al—C permanent magnets are disclosed. The magnets have high coercivities (about 4.8 kOe and 5.2 kOe) and high magnetization values. An intennetallic composition includes a ternary transition metal modified manganese aluminum alloy Mn—Al—Fe, Mn—Al—Ni, or Mn—Al—Co having at least about 80% of a magnetic ? phase and permanent magnetic properties. The alloy may have a saturation magnetization value of at least 96 emu/g with approximately 5% ternary transition metal replacing Al. The alloy may also have a saturation magnetization value of at least 105 emu/g with 10% ternary transition metal replacing Al.

Abstract: A bulky consolidated nanostructured manganese aluminum alloy includes at least about 80% of a magnetic ? phase and having a macroscopic composition of MnXAlYDoZ, where Do is a dopant, X ranges from 52-58 atomic %, Y ranges from 42-48 atomic %, and Z ranges from 0 to 3 atomic %. A method for producing a bulky nanocrystalline solid is provided. The method includes melting a mixture of metals to form a substantially homogenous solution. The method also includes casting the solution to form ingots, measuring compositions of the ingots; crushing the ingots to form crushed powders, and milling the crushed powders to form nanocrystalline powders. The method further includes verifying the presence of ? phase and determining the amount of the ? phase, and simultaneously consolidating the nanocrystalline powders into a bulky nanocrystalline solid and undergoing phase transformation from ? phase to at least 80% ? phase, ? and ?2 phases.

Abstract: This invention provides a system and method that improves the sensitivity and localization capabilities of Magnetic Particle Imaging (MPI) by using combinations of time-varying and static magnetic fields. Combinations of magnetic fields can be used to distribute the signals coming from the magnetic particles among the harmonics and other frequencies in specific ways to improve sensitivity and to provide localization information to speed up or improve the signal-to-noise ratio (SNR) of imaging and/or eliminate the need for saturation fields currently used in MPI. In various embodiments, coils can be provided to extend the sub-saturation region in which nanoparticles reside; to provide a static field offset to bring nanoparticles nearer to saturation; to introduce even and odd harmonics that can be observed; and/or to introduce combinations of frequencies for more-defined observation of signals from nanoparticles.

Abstract: This invention provides a system and method that improves the sensitivity and localization capabilities of Magnetic Particle Imaging (MPI) by using combinations of time-varying and static magnetic fields. Combinations of magnetic fields can be used to distribute the signals coming from the magnetic particles among the harmonics and other frequencies in specific ways to improve sensitivity and to provide localization information to speed up or improve the signal-to-noise ratio (SNR) of imaging and/or eliminate the need for saturation fields currently used in MPI. In various embodiments, coils can be provided to extend the sub-saturation region in which nanoparticles reside; to provide a static field offset to bring nanoparticles nearer to saturation; to introduce even and odd harmonics that can be observed; and/or to introduce combinations of frequencies for more-defined observation of signals from nanoparticles.

Abstract: The present invention is a nanoparticle composition composed of an iron core with an iron oxide shell which is optionally coated with a micro-emulsion. The disclosed nanoparticle compositions are disclosed for use in hyperthermia treatment and imaging of cancer.

Abstract: A method of joining at least two parts includes steps of dispersing a joining material comprising a multi-phase nanocrystalline magnetic metal-aluminum powder at an interface between the at least two parts to be joined and applying an alternating magnetic field (AMF). The AMF has a magnetic field strength and frequency suitable for inducing magnetic hysteresis losses in the metal-aluminum powder and is applied for a period that raises temperature of the metal-aluminum powder to an exothermic transformation temperature. At the exothermic transformation temperature, the metal-aluminum powder melts and resolidifies as a metal aluminide solid having a non-magnetic configuration.

Abstract: Alloys, formed by a eutectic transformation of the type Fe25-35 Ni15-25 Mn30-40 Al10-20 MO-5, are disclosed. M is selected from chromium, molybdenum, carbon and combinations thereof. The alloys have high strength and ductility. The alloys are prepared from readily available transition metals, and can be used in applications where properties similar to steel are necessary or advantageous.

Abstract: Biphasic alloys, formed through a spinodal decomposition process, are disclosed. The alloys have improved strength and hardness, over single phase alloys, due to coherency strain between the phases. They are prepared from readily available transition metals, and they can be used to make large, high-strength parts, for example, of types that cannot be made by extrusion, forging or cold working techniques.

Abstract: Nanostructured Mn—Al and Mn—Al—C permanent magnets are disclosed. The magnets have high coercivities (˜4.8 kOe and 5.2 kOe, respectively) and high saturation magnetization values. The magnets are prepared from cost effective and readily available elements using a novel mechanical milling and annealing method.

Abstract: The present invention is a nanoparticle composition composed of an iron core with an iron oxide shell which is optionally coated with a micro-emulsion. The disclosed nanoparticle compositions are disclosed for use in hyperthermia treatment and imaging of cancer.

Abstract: This invention provides a system and method that improves the sensitivity and localization capabilities of Magnetic Particle Imaging (MPI) by using combinations of time-varying and static magnetic fields. Combinations of magnetic fields can be used to distribute the signals coming from the magnetic particles among the harmonics and other frequencies in specific ways to improve sensitivity and to provide localization information to speed up or improve the signal-to-noise ratio (SNR) of imaging and/or eliminate the need for saturation fields currently used in MPI. In various embodiments, coils can be provided to extend the sub-saturation region in which nanoparticles reside; to provide a static field offset to bring nanoparticles nearer to saturation; to introduce even and odd harmonics that can be observed; and/or to introduce combinations of frequencies for more-defined observation of signals from nanoparticles.

Abstract: A cutting tool (10) comprises a shank (12) for receiving a cutting insert (14) and a block (16) for delivering a flow of fluid to the cutting insert (14). Fluid is delivered to the cutting insert (14) though a fluid passageway (18) that extends through the shank (12) and the block (16). The block (16) is pivotable mounted on the shank (12). The block (16) pivots about screw (22) between a first and a second position. In the first position the block (16) is held in sealing arrangement with the shank (12) to allow the passage of a coolant through the fluid passage (18) to the cutting insert (14). In the second position the block (16) has moved to allow removal of the cutting insert (14) from the shank (12).

Abstract: Biphasic alloys, formed through a spinodal decomposition process, are disclosed. The alloys have improved strength and hardness, over single phase alloys, due to coherency strain between the phases. They are prepared from readily available transition metals, and they can be used to make large, high-strength parts, for example, of types that cannot be made by extrusion, forging or cold working techniques.

Abstract: The present invention generally relates to molecules having Fc binding ability such as those with Fc receptor-like activity. The present invention also relates to the molecules, nucleic acids encoding the molecules, antagonist compounds, pharmaceutical compositions comprising the molecules and compounds, methods for testing potential antagonists, methods for producing the polypeptides, methods of treatment of disease and other aspects.