Abstract: The disclosed computer-implemented method for generating remedy recommendations for power and performance issues within semiconductor software and hardware. For example, the disclosed systems and methods can apply a rule-based model to telemetry data to generate rule-based root-cause outputs as well as telemetry-based unknown outputs. The disclosed systems and methods can further apply a root-cause machine learning model to the telemetry-based unknown outputs to analyze deep and complex failure patterns with the telemetry-based unknown outputs to ultimately generate one or more root-cause remedy recommendations that are specific to the identified failure and the client computing device that is experiencing that failure.

Abstract: Antibodies that bind ICOS (Inducible T cell Co-Stimulator). Therapeutic use of anti-ICOS antibodies for modulating the ratio between regulatory T cells and effector T cells, to stimulate the immune system of patients, including use in treating cancers. Methods of producing anti-ICOS antibodies, including species cross-reactive antibodies, using transgenic knock-out mice.

Abstract: Disclosed is a robot apparatus with a capable and highly maneuverable drive system incorporating two differential swerve drive pods. The robot apparatus further includes a claw mechanism for grasping an object, a passthrough mechanism for moving the object horizontally and a lift mechanism for moving the object vertically. The robot apparatus allows for rapid manipulation and movement of objects such as cones.

Abstract: The disclosed computer-implemented method for generating remedy recommendations for power and performance issues within semiconductor software and hardware. For example, the disclosed systems and methods can apply a rule-based model to telemetry data to generate rule-based root-cause outputs as well as telemetry-based unknown outputs. The disclosed systems and methods can further apply a root-cause machine learning model to the telemetry-based unknown outputs to analyze deep and complex failure patterns with the telemetry-based unknown outputs to ultimately generate one or more root-cause remedy recommendations that are specific to the identified failure and the client computing device that is experiencing that failure.

Abstract: An electric pushback vehicle includes a frame having a forward portion and a rear portion. The vehicle further includes front drive axle and a rear drive axle configured to communicate power to ground engaging members. A traction battery is housed within the electric pushback vehicle and provides electric power to an electric motor to drive an output shaft. A transmission is connected to receive mechanical power from the electric motor through a torque converter.

Abstract: Methods and devices are provided for processing data using a neural network. Activations from a previous layer of the neural network are received by a layer of the neural network. Weighted values, to be applied to values of elements of the activations, are determined based on a spatial correlation of the elements and a task error output by the layer. The weighted values are applied to the values of the elements and a combined error is determined based on the task error and the spatial correlation.

Abstract: An electronic device includes a hand held base assembly that includes circuitry including memory and firmware executed by a processor or microcontroller of the circuitry; and a cartridge assembly that includes memory that is read by the firmware of the handheld base assembly. The cartridge assembly and the handheld base assembly are configured to removably couple together to define the electronic device for producing an aerosol for inhalation by a person. An enclosed air passageway is defined by the cartridge assembly and by the handheld base assembly, which isolates the airflow from the electronics of the device. The enclosed air passageway extends between the opening of the mouthpiece for taking a breath and a diaphragm of the handheld base assembly, movement of the diaphragm changing the air pressure within an enclosed interior space having a pressure sensor for trigging the pressure sensor when a breath is taken.

Abstract: The present application relates to treating and/or preventing prostate cancer, including metastatic and/or castrate-resistant prostate cancer, in a subject in need of treatment having particular somatic AR tumor biomarker status, comprising administering a compound of Formula (I), or a pharmaceutically acceptable salt, enantiomer, stereoisomer, solvate, polymorph, isotopic derivative, or prodrug thereof, wherein R1, R2, R3, X1, X2, X3, X4, and n are defined herein.

Abstract: A cold gas thruster having a two-stage solenoid is provided. Pressurized gas from the inlet flows to the back side of the piston to hold the piston closed. The pressure is maintained by a check ball held by the solenoid armature. When the solenoid is energized, the armature allows the check ball to move to bleed off the pressure holding the piston closed. The piston moves away from its seat and allows the pressurized gas to flow to the outlet creating thrust. When the solenoid coil is de-energized, the check ball is forced against its seat, which blocks the escape of pressure on the back side of the piston, so that it can re-pressurize back up to the inlet pressure. This creates a force imbalance and moves the piston to close the valve and stop the thrust. Different nozzles can be used for different thrust profiles without changing the solenoid.

Abstract: Shader source code performance prediction is described. In accordance with the described techniques, an update to shader source code for implementing a shader is received. A prediction of performance of the shader on a processing unit is generated based on the update to the shader source code. Feedback about the update is output. The feedback includes the prediction of performance of the shader. In one or more implementations, generating the prediction of performance of the shader includes compiling the shader source code with the update to generate a representation of the shader, inputting the representation of the shader to one or more machine learning models, and receiving the prediction of performance of the shader as an output from the one or more machine learning models.

Abstract: At least one computer readable medium encoded with instructions that, when executed on a computer system, perform a method for determining one or more fluency characteristics of a writer from a piece of their prepared text and providing data to enable characterisation of the writer fluency. The method includes the steps of receiving text data carrying information on the piece of writing to be characterised; enumerating a set of sentences in the piece of writing, wherein each sentence is identified by applying a set of stored rules to the text data; determining a sentence type for each sentence within the piece of text by relating data carrying information on each sentence to stored rules and/or type data; aggregating a data set dependent on the sentence types identified and dependent on a defined aggregation operation; Characterisation data carrying information writer fluency measured dependent on the data set is generated.

Abstract: Systems, apparatuses, and methods for detecting personal-space violations in artificial intelligence (AI) based non-player characters (NPCs) are disclosed. An AI engine creates a NPC that accompanies and/or interacts with a player controlled by a user playing a video game. During gameplay, measures of context-dependent personal space around the player and/or one or more NPCs are generated. A control circuit monitors the movements of the NPC during gameplay and determines whether the NPC is adhering to or violating the measures of context-dependent personal space. The control circuit can monitor the movements of multiple NPCs simultaneously during gameplay, keeping a separate score for each NPC. After some amount of time has elapsed, the scores of the NPCs are recorded, and then the scores are provided to a machine learning engine to retrain the AI engines controlling the NPCs.

Abstract: An apparatus includes a processor configured to determine a first distribution associated with an artificial agent based on behavior associated with the artificial agent and a second distribution based on behavior of a user. The processor is further configured to generate a human-likeness similarity measurement by comparing the first distribution to the second distribution and modify the behavior of the artificial agent in response to the similarity measurement failing to satisfy a similarity threshold.

Abstract: A dual-optical displacement sensor system includes a scanner including a first and second scanner head including optical displacement sensors providing a first and second beam having a first optical axis (OA) and a second OA. A computing device or programmed circuit is coupled to receive time versus position data from measurements involving alignment target(s) including at least one knife edge pair including a first and second knife edge oriented in a first plane of the alignment target that is essentially perpendicular to the OAs positioned between the scanner heads for interacting with the beams, and implement at least one equation to analyze the data for determining a degree of alignment of the first and second OA. Using the degree of alignment, an algorithm is for automatic alignment of the OAs or assist instructions for a user alignment of the OAs that provides guiding steps for the user for the alignment.

Abstract: The disclosure features pharmaceutical compositions formed from prodrug dimers for the extended delivery of a drug and for the treatment of a disease or condition.

Abstract: A load break tool for opening a high load electrical switch having a first switch contact and a second switch contact. The load break tool includes a main body extending along a longitudinal axis between a first end and a second end. The main body is movable between an extended configuration and a retracted configuration. A first contact is coupled to the first end and configured to selectively couple with the first switch contact. A second contact is coupled to the second end and configured to selectively couple with the second switch contact. In the retracted configuration the first contact is in electrical communication with the second contact. A spring assembly is mounted in the main body for biasing the main body to the retracted configuration, the spring assembly including a compression spring.

Abstract: Shader source code performance prediction is described. In accordance with the described techniques, an update to shader source code for implementing a shader is received. A prediction of performance of the shader on a processing unit is generated based on the update to the shader source code. Feedback about the update is output. The feedback includes the prediction of performance of the shader. In one or more implementations, generating the prediction of performance of the shader includes compiling the shader source code with the update to generate a representation of the shader, inputting the representation of the shader to one or more machine learning models, and receiving the prediction of performance of the shader as an output from the one or more machine learning models.

Abstract: A dividing wall column is used in an alkylation process flow scheme to fractionate an alkylate reactor effluent to produce an iso-butane-rich stream as a recycle feed for the alkylation reactor while also separating iso-butane, normal butane and alkylate as separate product streams depending on the reactor effluent composition. In an optional embodiment, the scheme may contain propane.

Abstract: The disclosure relates to compounds and compositions for sustained release of ocular therapeutics.