Abstract: A compound of formula (I) and salts and solvates thereof, wherein RL is a linker for connection to a cell binding agent, which is formula (IIa) wherein Q is a tripeptide residue of formula (A), where x is 1 or 2, —C(?O)-Qx-NH— is a dipeptide residue; X is: formula (B), where a=0 to 5, b=0 to 16, c=0 or 1, d=0 to 5; and GL is a linker for connecting to a Ligand Unit.

Abstract: A compound of formula (I) wherein RL is a linker for connection to a cell binding agent.

Abstract: A surgical knife handle comprising a handle body (102) and a blade receiving portion (104) defined at a first end of the handle body, which blade receiving portion comprises a blade receiving bore and a blade support (118) extending to a first side of the blade receiving bore. A surgical knife comprising a handle, a blade defined at a first end of the handle and a blade support extending to a first side of the blade.

Abstract: A surgical knife handle comprising a handle body (102) and a blade receiving portion (104) defined at a first end of the handle body, which blade receiving portion comprises a blade receiving bore and a blade support (118) extending to a first side of the blade receiving bore. A surgical knife comprising a handle, a blade defined at a first end of the handle and a blade support extending to a first side of the blade.

Abstract: A presentation system and method for presenting information to an audience within a space hat includes a plurality of mobile projectors and a master presentation unit that can be moved into a presentation space and associated where the projectors and master unit are quickly linkable via a network and where the master unit expedites the system configuration process to allow the system user to manipulate images presented by all of the projectors.

Abstract: A presentation system for presenting information to an audience within a space, the system comprising a control interface, a master presentation unit including a flat panel display screen and a processor, the screen including a master space and a slave presentation assembly including a slave presentation surface and a first projector for projecting images on the slave presentation surface, the master unit processor linkable to the interface to receive commands therefrom, the processor programmed to monitor for a command from the interface to flip an image from the master space to the slave space and, when a command to flip an image is received, causing the image from the master space to be presented in the slave space.

Abstract: The present invention includes interactive communication systems that incorporate several beneficial embodiments including an interactive tray system, an electronic presentation messaging system, an interactive podium, and a key drive system. The interactive tray system enables a single, transferable interactive unit to be fastened to a communication medium, turning into a fully interactive medium. The electronic presentation messaging system enables the e-mailing of presentations and notes to and from components of the interactive communication system. The interactive podium increases conventional podium mobility, enabling both the presenter, and podium, to move and be moved about the room without attention to wired connections.

Abstract: A presentation system for presenting information to an audience within a space, the system comprising a control interface, a master presentation unit including a flat panel display screen and a processor, the screen including a master space and a slave presentation assembly including a slave presentation surface and a first projector for projecting images on the slave presentation surface, the master unit processor linkable to the interface to receive commands therefrom, the processor programmed to monitor for a command from the interface to flip an image from the master space to the slave space and, when a command to flip an image is received, causing the image from the master space to be presented in the slave space.

Abstract: A presentation method and system for presenting information to an audience within a space that mimics a flip chart assembly, the system including a control interface, a communication network and a master presentation unit including a processor and a master display screen, the master screen juxtaposed within the space so as to be viewable by the audience within the space, the processor operable to transmit an image displayed on the master screen over the network upon user command and a slave presentation unit including a slave presenter operable to receive and present an image to the audience within the space that is transmitted by the master unit to the slave unit over the network such that the master unit can be used to create a new image while the first image is simultaneously presented.

Abstract: An interactive display system is provided including a support frame having a vertical positioning element that counterbalances the weight of an attached interactive display, for example a touch-sensitive display. The support frame optionally includes a power supply increasing the range of mobility of the interactive display system by eliminating the need for power cord and power outlet connections. One exemplary support frame for an interactive display includes a base element, at least one support extending vertically from the base element, and a positioning element housed within the at least one support. The positioning element counterbalances the weight of the interactive display allowing vertical repositioning of the interactive display with a force of less than about 25 pounds.