Abstract: The disclosure is directed to improved methods for preparing substituted quinolinylcyclohexylpropanamide compounds.

Abstract: Marine shellfish, such as bivalve mollusks, are grown to edible size in surface-floating, partly submerged trays comprising a frame enclosed with a mesh having a size small enough to retain the species to be grown. A plurality of these trays are connected together in series and anchored in nutrient-providing water, such as an estuary, that while protected nonetheless is subject to wave action. These trays are attended by periodically flipping them over every two to three days and, if necessary, removing any fouling that may have built up on the undersurface. By means of this system, marketable-size oysters can, for example, be produced in fourteen months compared to the twenty-two to forty-eight months of other methods.