Patents by Inventor Ian Pragnell

Ian Pragnell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stem cell inhibitor
    Patent number: 6558925
    Abstract: The present invention provides a Stem Cell Inhibitor (SCI) protein which comprises at least one amino acid alteration from its native form which protein does not significantly aggregate but which retains substantially unaltered stem cell inhibitory activity. The alteration is preferably a conservative subsitution of a charged amino acid residue. Such proteins may be used in treating stem cells in a patient undergoing chemotherapy.
    Type: Grant
    Filed: September 11, 1998
    Date of Patent: May 6, 2003
    Assignee: Wyeth
    Inventors: Gerard Graham, Ian Pragnell
  • STEM CELL INHIBITOR
    Publication number: 20010010935
    Abstract: The present invention provides a Stem Cell Inhibitor (SCI) protein which comprises at least one amino acid alteration from its native form which protein does not significantly aggregate but which retains substantially unaltered stem cell inhibitory activity. The alteration is preferably a conservative subsitution of a charged amino acid residue. Such proteins may be used in treating stem cells in a patient undergoing chemotherapy.
    Type: Application
    Filed: September 11, 1998
    Publication date: August 2, 2001
    Inventors: GERARD GRAHAM, IAN PRAGNELL
  • Macrophage inflammatory protein variants
    Patent number: 5936067
    Abstract: The present invention provides a Stem Cell Inhibitor (SCT) protein which comprises at least one amino acid alteration from its active form which protein does not significantly aggregate but which retains substantially unaltered stem cell inhibitory activity. The alteration is preferably a conservative substitution of a charged amino acid residue. Such proteins may be used in treating stem cells in a patient undergoing chemotherapy.
    Type: Grant
    Filed: January 29, 1996
    Date of Patent: August 10, 1999
    Assignee: Genetics Institute, Inc.
    Inventors: Gerard Graham, Ian Pragnell