Patents by Inventor Ibon Garitaonandia

Ibon Garitaonandia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of neural cells derived from human pluripotent stem cells for the treatment of neurodegenerative diseases
    Patent number: 11007232
    Abstract: The present invention is based in part methods for treating neurodegenerative diseases and disorders. Specifically, the present invention disclose methods for treating neurodegenerative disorders suing neural stem cells (NSCs) and/or pluripotent stem cell (PSC) derived neurons or neuron precursor cells. The present invention also discloses methods to induce endogenous dopaminergic neurons to release dopamine and increase the levels of dopamine in a subject.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: May 18, 2021
    Assignee: International Stem Cell Corporation
    Inventors: Russell A. Kern, Rodolfo Gonzalez, Ibon Garitaonandia
  • Method of prevention of neurological diseases
    Patent number: 10258632
    Abstract: Provided herein are small molecules that have a neuroprotective or modulatory effect in the nervous system. The small molecules provided herein modulate dopaminergic neuronal activity. Also provided herein are methods of for the prophylaxis of or preventing the progression of Parkinson's Disease (PD).
    Type: Grant
    Filed: June 3, 2013
    Date of Patent: April 16, 2019
    Assignee: International Stem Cell Corporation
    Inventors: Rodolfo Gonzalez, Ibon Garitaonandia, Russell A. Kern
  • USE OF NEURAL CELLS DERIVED FROM HUMAN PLURIPOTENT STEM CELLS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES
    Publication number: 20180339001
    Abstract: The present invention is based in part methods for treating neurodegenerative diseases and disorders. Specifically, the present invention disclose methods for treating neurodegenerative disorders suing neural stem cells (NSCs) and/or pluripotent stem cell (PSC) derived neurons or neuron precursor cells. The present invention also discloses methods to induce endogenous dopaminergic neurons to release dopamine and increase the levels of dopamine in a subject.
    Type: Application
    Filed: August 6, 2018
    Publication date: November 29, 2018
    Inventors: Russell A. Kern, Rodolfo Gonzalez, Ibon Garitaonandia
  • USE OF NEURAL CELLS DERIVED FROM HUMAN PLURIPOTENT STEM CELLS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES
    Publication number: 20180339000
    Abstract: The present invention is based in part methods for treating neurodegenerative diseases and disorders. Specifically, the present invention disclose methods for treating neurodegenerative disorders suing neural stem cells (NSCs) and/or pluripotent stem cell (PSC) derived neurons or neuron precursor cells. The present invention also discloses methods to induce endogenous dopaminergic neurons to release dopamine and increase the levels of dopamine in a subject.
    Type: Application
    Filed: August 6, 2018
    Publication date: November 29, 2018
    Inventors: Russell A. Kern, Rodolfo Gonzalez, Ibon Garitaonandia
  • Use of neural cells derived from human pluripotent stem cells for the treatment of neurodegenerative diseases
    Patent number: 10039794
    Abstract: The present invention is based in part methods for treating neurodegenerative diseases and disorders. Specifically, the present invention disclose methods for treating neurodegenerative disorders suing neural stem cells (NSCs) and/or pluripotent stem cell (PSC) derived neurons or neuron precursor cells. The present invention also discloses methods to induce endogenous dopaminergic neurons to release dopamine and increase the levels of dopamine in a subject.
    Type: Grant
    Filed: February 14, 2014
    Date of Patent: August 7, 2018
    Assignee: International Stem Cell Corporation
    Inventors: Russell A. Kern, Rodolfo Gonzalez, Ibon Garitaonandia
  • Derivation of neural stem cells and dopaminergic neurons from human pluripotent stem cells
    Patent number: 9926529
    Abstract: The present invention is based in part on a chemically defined method of generating neural stem cells (NSCs) and dopaminergic (DA) neurons from human pluripotent stem cells (hPSCs). The DA neurons of the invention can be derived from hPSCs and NSCs. The present invention also provides reagents and kits useful for the derivation of neural stem cells and dopaminergic neurons from human pluripotent stem cells.
    Type: Grant
    Filed: April 23, 2013
    Date of Patent: March 27, 2018
    Assignee: International Stem Cell Corporation
    Inventors: Rodolfo Gonzalez, Ibon Garitaonandia, Ruslan Semechkin
  • Method of Prevention of Neurological Diseases
    Publication number: 20150094289
    Abstract: Provided herein are small molecules that have a neuroprotective or modulatory effect in the nervous system. The small molecules provided herein modulate dopaminergic neuronal activity. Also provided herein are methods of for the prophylaxis of or preventing the progression of Parkinson's Disease (PD).
    Type: Application
    Filed: June 3, 2013
    Publication date: April 2, 2015
    Inventors: Rudolfo Gonzalez, Ibon Garitaonandia, Ruslan Semechkin
  • Derivation of Neural Stem Cells and Dopaminergic Neurons from Human Pluripotent Stem Cells
    Publication number: 20150087541
    Abstract: The present invention is based in part on a chemically defined method of generating neural stem cells (NSCs) and dopaminergic (DA) neurons from human pluripotent stem cells (hPSCs). The DA neurons of the invention can be derived from hPSCs and NSCs. The present invention also provides reagents and kits useful for the derivation of neural stem cells and dopaminergic neurons from human pluripotent stem cells.
    Type: Application
    Filed: April 23, 2013
    Publication date: March 26, 2015
    Inventors: Rodolfo Gonzalez, Ibon Garitaonandia, Ruslan Semechkin
  • USE OF NEURAL CELLS DERIVED FROM HUMAN PLURIPOTENT STEM CELLS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES
    Publication number: 20140314721
    Abstract: The present invention is based in part methods for treating neurodegenerative diseases and disorders. Specifically, the present invention disclose methods for treating neurodegenerative disorders suing neural stem cells (NSCs) and/or pluripotent stem cell (PSC) derived neurons or neuron precursor cells. The present invention also discloses methods to induce endogenous dopaminergic neurons to release dopamine and increase the levels of dopamine in a subject.
    Type: Application
    Filed: February 14, 2014
    Publication date: October 23, 2014
    Applicant: INTERNATIONAL STEM CELL CORPORATION
    Inventors: Ruslan Semechkin, Rudolfo Gonzalez, Ibon Garitaonandia
  • High throughput assays for inhibitors and activators of PAQR receptors
    Patent number: 8809001
    Abstract: The subject invention provides methods of screening compounds or ligands that interact with human and/or non-human PAQR receptors or fungal osmotin receptors. These methods utilize a colorimetric assay to ascertain whether a compound binds to and activates a PAQR receptor or the osmotin receptor.
    Type: Grant
    Filed: September 23, 2008
    Date of Patent: August 19, 2014
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Thomas Lyons, Brian R. Kupchak, Jessica L. Smith, Ibon Garitaonandia
  • High Throughput Assays for Inhibitors and Activators of PAQR Receptors
    Publication number: 20100261178
    Abstract: The subject invention provides methods of screening compounds or ligands that interact with human and/or non-human PAQR receptors or fungal osmotin receptors. These methods utilize a colorimetric assay to ascertain whether a compound binds to and activates a PAQR receptor or the osmotin receptor.
    Type: Application
    Filed: September 23, 2008
    Publication date: October 14, 2010
    Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Thomas Lyons, Brian R. Kupchak, Jessica L. Smith, Ibon Garitaonandia