Abstract: To provide a means capable of obtaining further excellent cellular adhesiveness than in a case where a surface of a cell culture substrate (cell culture vessel) is coated using polytetrahydrofurfuryl acrylate (PTHFA). Provided is a cell culture substrate comprising a coating layer on at least one side of a polymer substrate, wherein the coating layer includes a copolymer comprising more than 20% by mole and less than 100% by mole of a structural unit (1) derived from furfuryl (meth)acrylate represented by Formula (1) and more than 0% by mole and less than 80% by mole of a structural unit (2) derived from ethylenically unsaturated monomer having a hydroxyl group (the total of the structural unit (1) and the structural unit (2) is 100% by mole).

Abstract: This invention is to provide a means capable of obtaining excellent cell proliferation activity without depending on a thickness of a coating layer in a technique of coating a cell culture substrate (cell culture vessel) using a polymer. Provided is a cell culture substrate comprising a coating layer on at least one surface of a polymer substrate, wherein the coating layer includes a copolymer comprising more than 40% by mole and less than 100% by mole of a structural unit (1) derived from carboxyalkyl (meth)acrylate represented by Formula (1) and more than 0% by mole and less than 60% by mole of a structural unit (2) derived from ethylenically unsaturated monomer having a hydroxyl group (the total of the structural unit (1) and the structural unit (2) is 100% by mole).

Abstract: Provided is a means capable of predicting a formation of thrombus or a risk thereof in a medical device performing blood circulation by a pump, by a simple and minimally invasive method. A method for predicting a formation of thrombus or a risk thereof in a medical device performing blood circulation by a pump, wherein it is predicted that thrombus is formed or there is a risk thereof in the medical device when a concentration or expression amount of ADAM28 in a body fluid sample collected from a subject wearing the medical device is elevated compared with a reference value.

Abstract: Provided is a means capable of determining the development of myocarditis or the risk thereof by a simple and minimally invasive method. A method of determining the development of myocarditis or risk thereof, wherein it is determined that myocarditis is developed or there is a risk thereof when a concentration or expression amount of ADAM28 in a body fluid sample collected from a subject is reduced compared with a reference value.

Abstract: To provide a means capable of providing excellent cell adhesion to a polymer substrate (particularly, a hydrophilic polymer substrate) as compared to the case of performing a surface treatment with polytetrahydrofurfuryl acrylate (PTHFA). Provided is a cell culture substrate comprising a coating layer on at least one side of a polymer substrate, wherein the coating layer includes a copolymer having more than 40% by mole and less than 100% by mole of a structural unit derived from furfuryl (meth)acrylate represented by Formula and more than 0% by mole and less than 60% by mole of a structural unit derived from ethylenically unsaturated monomer having a carboxylic group (the total of the structural unit and the structural unit is 100% by mole).

Abstract: This invention is to provide a means capable of providing excellent cell proliferation activity to a hydrophilic polymer substrate. Provided is a cell culture substrate comprising a coating layer on at least one surface of a hydrophilic polymer substrate, wherein the coating layer includes a polymer comprising a structural unit derived from furfuryl (meth)acrylate represented by Formula, and a ratio of mass of the polymer contained per unit area of the coating layer is more than 2 ?g/cm2.

Abstract: To provide a means capable of obtaining further excellent cellular adhesiveness than in a case where a surface of a cell culture substrate (cell culture vessel) is coated using polytetrahydrofurfuryl acrylate (PTHFA). Provided is a cell culture substrate comprising a coating layer on at least one side of a polymer substrate, wherein the coating layer includes a copolymer comprising more than 20% by mole and less than 100% by mole of a structural unit (1) derived from furfuryl (meth)acrylate represented by Formula (1) and more than 0% by mole and less than 80% by mole of a structural unit (2) derived from ethylenically unsaturated monomer having a hydroxyl group (the total of the structural unit (1) and the structural unit (2) is 100% by mole).

Abstract: This invention is to provide a means capable of obtaining excellent cell proliferation activity without depending on a thickness of a coating layer in a technique of coating a cell culture substrate (cell culture vessel) using a polymer. Provided is a cell culture substrate comprising a coating layer on at least one surface of a polymer substrate, wherein the coating layer includes a copolymer comprising more than 40% by mole and less than 100% by mole of a structural unit (1) derived from carboxyalkyl (meth)acrylate represented by Formula (1) and more than 0% by mole and less than 60% by mole of a structural unit (2) derived from ethylenically unsaturated monomer having a hydroxyl group (the total of the structural unit (1) and the structural unit (2) is 100% by mole).

Abstract: The invention is to provide a means capable of achieving both cellular adhesiveness and antithrombogenicity with balance. Provided is a cell culture substrate comprising a coating layer on at least one side of a polymer substrate, wherein the coating layer includes a copolymer having 5 to 65% by mole of a structural unit (1) derived from alkoxyalkyl (meth)acrylate of Formula (1) and 95 to 35% by mole of a structural unit (2) derived from furfuryl (meth)acrylate of Formula (2) (the total of the structural unit (1) and the structural unit (2) is 100% by mole).

Abstract: The invention is to provide a cell culture substrate excellent in cellular adhesiveness regardless of a shape or design thereof.

Abstract: An ablation device includes a waveguide that guides a pulse laser output from a laser output unit, a laser emitting unit that focuses the pulse laser guided by the waveguide using a lens, emits the pulse laser to a living body tissue, causes multiphoton absorption in a focal position of the pulse laser, and performs ablation on the living body tissue; and a balloon that sets a focus of the pulse laser as the laser emitting unit is positioned at a desired position inside a living body lumen.