Abstract: Provided is a measurement method whereby the amount of unbound bilirubin (UB) can be exactly reflected whether a specimen contains a large amount of conjugated bilirubin or not. The measurement method for UB according to the present invention comprises decomposition step (i), decomposition stopping step (ii), contact step (iii) and detection step (iv). In decomposition step (i), a blood sample containing unconjugated bilirubin (iD-Bil) and conjugated bilirubin (D-Bil) is subjected to an oxidative decomposition reaction of UB in iD-Bil and D-Bil. In decomposition stopping step (ii), the oxidative decomposition reaction is stopped to give a decomposition product of the sample. In contact step (iii), the decomposition product of the sample is contacted with UnaG that is capable of specifically binding to iD-Bil. Separately, an unreacted sample, which is the blood sample not subjected to decomposition step (i), is contacted with UnaG too.

Abstract: Provided is a measurement method whereby the amount of unbound bilirubin (UB) can be exactly reflected whether a specimen contains a large amount of conjugated bilirubin or not. The measurement method for UB according to the present invention comprises decomposition step (i), decomposition stopping step (ii), contact step (iii) and detection step (iv). In decomposition step (i), a blood sample containing unconjugated bilirubin (iD-Bil) and conjugated bilirubin (D-Bil) is subjected to an oxidative decomposition reaction of UB in iD-Bil and D-Bil. In decomposition stopping step (ii), the oxidative decomposition reaction is stopped to give a decomposition product of the sample. In contact step (iii), the decomposition product of the sample is contacted with UnaG that is capable of specifically binding to iD-Bil. Separately, an unreacted sample, which is the blood sample not subjected to decomposition step (i), is contacted with UnaG too.

Abstract: A fluorine insolubilizer capable of sufficiently insolubilizing fluorine within a short time contains calcium hydrogen phosphate dihydrate in an amount of 95-40 mass % and hydroxy or hydroxyl apatite in an amount of 5-60 mass % for a total of 100 mass %.

Abstract: A fluorine insolubilizer capable of sufficiently insolubilizing fluorine within a short time contains calcium hydrogen phosphate dihydrate in an amount of 95-40 mass % and apatite hydroxide in an amount of 5-60 mass % for a total of 100 mass %.

Abstract: A method of quickly and safely determining the component concentrations of a three-component mixture comprising substantially sulfuric acid, hydrogen fluoride and water, which comprises measuring at least one set of three physical quantities of (1) temperature, (2) ultrasonic wave propagation velocity and (3) electric conductivity or viscosity of the three-component mixture and converting the obtained values to the component concentrations on the basis of a working curve representing the relationship between each component concentration of the three-component mixture and the three physical quantities; and a method of continuous production of hydrogen fluoride for controlling a water concentration in the reaction system by using this method.