Patents by Inventor Igor Rakov

Igor Rakov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Selective androgen receptor modulators, analogs and derivatives thereof and uses thereof
    Patent number: 8110562
    Abstract: This invention provides nuclear hormone receptor binding compounds, compositions comprising the same and methods of uses thereof in treating a variety of diseases or conditions in a subject, including, inter-alia, prostate cancer and/or diseases or disorders of bone and muscle.
    Type: Grant
    Filed: July 19, 2007
    Date of Patent: February 7, 2012
    Assignees: University of Tennessee Research Foundation, The Ohio State University Research Foundation
    Inventors: James T. Dalton, Duane D. Miller, Igor Rakov, Casey Bohl, Michael L. Mohler
  • Selective androgen receptor modulators, analogs and derivatives thereof and uses thereof
    Publication number: 20110077221
    Abstract: This invention provides nuclear hormone receptor binding compounds, compositions comprising the same and methods of uses thereof in treating a variety of diseases or conditions in a subject, including, inter-alia, prostate cancer and/or diseases or disorders of bone and muscle.
    Type: Application
    Filed: July 19, 2007
    Publication date: March 31, 2011
    Inventors: James T. Dalton, Duane D. Miller, Igor Rakov, Casey Bohl, Michael L. Mohler
  • Substituted tetrahydroisoquinoline compounds, methods of making, and their use
    Patent number: 7718672
    Abstract: Disclosed are novel substituted tetrahydroisoquinoline compounds, pharmaceutical compositions containing the compounds, methods of making the compounds, and methods of using the compounds to destroy a target cell, such as a cancer cell, and to treat or prevent a cancerous condition.
    Type: Grant
    Filed: July 9, 2007
    Date of Patent: May 18, 2010
    Assignee: University of Tennessee Research Foundation
    Inventors: Duane D. Miller, Eldon E. Geisert, Jr., Michael Mohler, Victor Nikulin, Oleg Kirichenko, Seoung Sung Hong, Gyong Suk Kang, Igor Rakov
  • Selective androgen receptor modulators, analogs and derivatives thereof and uses thereof
    Publication number: 20090156614
    Abstract: This invention provides new compounds and uses thereof in treating a variety of diseases or conditions in a subject, including, inter alia, prostate cancer, muscle wasting diseases and/or disorders or a bone-related diseases and/or disorders.
    Type: Application
    Filed: July 19, 2007
    Publication date: June 18, 2009
    Inventors: James T. Dalton, Duane D. Miller, Igor Rakov, Casey Bohl, Michael L. Mohler
  • Methylene-bridged selective androgen receptor modulators and methods of use thereof
    Publication number: 20080319009
    Abstract: This invention provides a class of androgen receptor targeting agents (ARTA). The agents define a new subclass of compounds, which are selective androgen receptor modulators (SARM). Several of the SARM compounds have been found to have an unexpected androgenic and anabolic activity of a nonsteroidal ligand for the androgen receptor. Other SARM compounds have been found to have an unexpected antiandrogenic activity of a nonsteroidal ligand for the androgen receptor.
    Type: Application
    Filed: July 30, 2007
    Publication date: December 25, 2008
    Inventors: James T. Dalton, Duane D. Miller, Igor Rakov
  • SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUNDS, METHODS OF MAKING, AND THEIR USE
    Publication number: 20070270460
    Abstract: Disclosed are novel substituted tetrahydroisoquinoline compounds, pharmaceutical compositions containing the compounds, methods of making the compounds, and methods of using the compounds to destroy a target cell, such as a cancer cell, and to treat or prevent a cancerous condition.
    Type: Application
    Filed: July 9, 2007
    Publication date: November 22, 2007
    Inventors: Duane Miller, Eldon Geisert, Michael Mohler, Victor Nikulin, Oleg Kirichenko, Seoung Hong, Gyong Kang, Igor Rakov
  • Methylene-bridged selective androgen receptor modulators and methods of use thereof
    Patent number: 7253210
    Abstract: This invention provides a class of androgen receptor targeting agents (ARTA). The agents define a new subclass of compounds, which are selective androgen receptor modulators (SARM). Several of the SARM compounds have been found to have an unexpected androgenic and anabolic activity of a nonsteroidal ligand for the androgen receptor. Other SARM compounds have been found to have an unexpected antiandrogenic activity of a nonsteroidal ligand for the androgen receptor.
    Type: Grant
    Filed: October 14, 2003
    Date of Patent: August 7, 2007
    Assignee: University of Tennessee Research Foundation
    Inventors: James T. Dalton, Duane D. Miller, Igor Rakov
  • Substituted tetrahydroisoquinoline compounds, methods of making, and their use
    Patent number: 7241774
    Abstract: The present invention relates to novel substituted tetrahydroisoquinoline compounds, pharmaceutical compositions containing the compounds, methods of making the compounds, and methods of using the compounds to destroy a target cell, such as a cancer cell, and to treat or prevent a cancerous condition.
    Type: Grant
    Filed: March 13, 2003
    Date of Patent: July 10, 2007
    Assignee: University of Tennessee Research Foundation
    Inventors: Duane D. Miller, Eldon E. Geisert, Jr., Michael Mohler, Victor Nikulin, Oleg Kirichenko, Seoung Sung Hong, Gyong Suk Kang, Igor Rakov
  • Methylene-bridged selective androgen receptor modulators and methods of use thereof
    Publication number: 20040147550
    Abstract: This invention provides a class of androgen receptor targeting agents (ARTA). The agents define a new subclass of compounds, which are selective androgen receptor modulators (SARM). Several of the SARM compounds have been found to have an unexpected androgenic and anabolic activity of a nonsteroidal ligand for the androgen receptor. Other SARM compounds have been found to have an unexpected antiandrogenic activity of a nonsteroidal ligand for the androgen receptor.
    Type: Application
    Filed: October 14, 2003
    Publication date: July 29, 2004
    Inventors: James T. Dalton, Duane D. Miller, Igor Rakov
  • Substituted tetrahydroisoquinoline compounds, methods of making, and their use
    Publication number: 20040019078
    Abstract: The present invention relates to novel substituted tetrahydroisoquinoline compounds, pharmaceutical compositions containing the compounds, methods of making the compounds, and methods of using the compounds to destroy a target cell, such as a cancer cell, and to treat or prevent a cancerous condition.
    Type: Application
    Filed: March 13, 2003
    Publication date: January 29, 2004
    Inventors: Duane D. Miller, Eldon E. Geisert, Michael Mohler, Victor Nikulin, Oleg Kirichenko, Seoung Sung Hong, Gyong Suk Kang, Igor Rakov