Patents by Inventor Igor Stojiljkovic
Igor Stojiljkovic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 7026157Abstract: The present invention relates to novel bacterial hemoglobin receptor proteins and genes that encode such proteins. The invention is directed toward the isolation, characterization, diagnostic and therapeutic use of bacterial hemoglobin receptor proteins, nucleic acid encoding such proteins, recombinant expression constructs comprising such nucleic acids and cells transformed therewith, and antibodies and epitopes of such hemoglobin receptor proteins. The invention relates particularly to hemoglobin receptor proteins and genes encoding such proteins from Neisseria species, especially N. meningitidis and serotypes thereof, and N. gonorrhoeae. Methods for the diagnostic and therapeutic use of the proteins, epitopes, antibodies and nucleic acids of the invention are also provided, including the use of the proteins, epitopes, antibodies and nucleic acids of the invention for the production of vaccines effectinve in providing immunization of a human against infection by pathogenic bacteria of Neisseria species.Type: GrantFiled: September 19, 2000Date of Patent: April 11, 2006Assignee: Oregon Health and Science UniversityInventors: Igor Stojiljkovic, Magdalene So, Vivian Hwa, Fred Heffron, Xavier Nassif
-
Patent number: 6277382Abstract: The present invention relates to novel bacterial hemoglobin receptor proteins and genes that encode such proteins. The invention is directed toward the isolation, characterization, diagnostic and therapeutic use of bacterial hemoglobin receptor proteins, nucleic acids encoding such proteins, recombinant expression constructs comprising such nucleic acids and cells transformed therewith, and antibodies and epitopes of such hemoglobin receptor proteins. The invention relates particularly to hemoglobin receptor proteins and genes encoding such proteins from Neisseria species, especially N. meningitidis and serotypes thereof, and N. gonorrhoeae. Methods for the diagnostic and therapeutic use of the proteins, epitopes, antibodies and nucleic acids of the invention are also provided, including the use of proteins, epitopes, antibodies and nucleic acids of the invention for the production of vaccines effective in providing immunization of human against infection by pathogenic bacteria of Neisseria species.Type: GrantFiled: August 19, 1997Date of Patent: August 21, 2001Assignee: Oregon Health Sciences UniversityInventors: Igor Stojiljkovic, Magdalene So, Vivian Hwa, Fred Heffron, Xavier Nassif
-
Patent number: 6123942Abstract: The present invention relates to a novel bacterial hemoglobin receptor protein and genes that encode such a protein. The invention is directed toward the isolation, characterization, diagnostic and therapeutic use of a bacterial hemoglobin receptor protein, nucleic acid encoding such a protein, recombinant expression constructs comprising such nucleic acids and cells transformed therewith, and antibodies and epitopes of such hemoglobin receptor proteins. The invention relates particularly to hemoglobin receptor proteins and genes encoding such proteins from Neisseria species, especially N. meningitidis. Methods for the diagnostic and therapeutic use of the proteins, epitopes, antibodies and nucleic acids of the invention are also provided, including the use of the proteins, epitopes, antibodies and nucleic acids of the invention for the production of vaccines effectinve in providing immunization of a human against infection by pathogenic bacteria of Neisseria species.Type: GrantFiled: December 15, 1997Date of Patent: September 26, 2000Assignee: Oregon Health Sciences UniversityInventors: Igor Stojiljkovic, Magdalene So, Vivian Hwa, Fred Heffron, Xavier Nassif
-
Patent number: 6121037Abstract: The present invention relates to novel bacterial hemoglobin receptor proteins and genes that encode such proteins. The invention is directed toward the isolation, characterization, diagnostic and therapeutic use of bacterial hemoglobin receptor proteins, nucleic acid encoding such proteins, recombinant expression constructs comprising such nucleic acids and cells transformed therewith, and antibodies and epitopes of such hemoglobin receptor proteins. The invention relates particularly to hemoglobin receptor proteins and genes encoding such proteins from Neisseria species, especially N. meningitidis and serotypes thereof, and N. gonorrhoeae. Methods for the diagnostic and therapeutic use of the proteins, epitopes, antibodies and nucleic acids of the invention are also provided, including the use of the proteins, epitopes, antibodies and nucleic acids of the invention for the production of vaccines effective in providing immunization of a human against infection by pathogenic bacteria of Neisseria species.Type: GrantFiled: October 2, 1995Date of Patent: September 19, 2000Inventors: Igor Stojiljkovic, Magdalene So, Vivian Hwa, Fred Heffron, Xavier Nassif
-
Patent number: 6066628Abstract: The present disclosure provides novel non-iron metalloporphyrins, especially those porphyrin complexes containing gallium or indium as the metal ion, and antibacterial compositions comprising artificial metalloporphyrins (such as protoporphyrin IX) completed with a metal ion selected from metal ions including, but not limited to, gadolinium, ruthenium copper, gallium, indium and manganese, and methods for inhibiting or killing bacteria and other microorganisms and for treating infections caused by microorganisms using the artificial metalloporphyrin of the present invention.Type: GrantFiled: January 9, 1998Date of Patent: May 23, 2000Assignee: Emory UniversityInventors: Igor Stojiljkovic, Gordon G. Churchward
-
Patent number: 5698438Abstract: The present invention relates to a novel bacterial hemoglobin receptor protein and genes that encode such a protein. The invention is directed toward the isolation, characterization, diagnostic and therapeutic use of a bacterial hemoglobin receptor protein, nucleic acid encoding such a protein, recombinant expression constructs comprising such nucleic acids and cells transformed therewith, and antibodies and epitopes of such hemoglobin receptor proteins. The invention relates particularly to hemoglobin receptor proteins and genes encoding such proteins from Neisseria species, especially N. meningitidis. Methods for the diagnostic and therapeutic use of the proteins, epitopes, antibodies and nucleic acids of the invention are also provided, including the use of the proteins, epitopes, antibodies and nucleic acids of the invention for the production of vaccines effective in providing immunization of a human against infection by pathogenic bacteria of Neisseria species.Type: GrantFiled: October 18, 1994Date of Patent: December 16, 1997Assignee: Oregon Health Sciences UniversityInventors: Igor Stojiljkovic, Magdalene So, Vivian Hwa, Fred Heffron, Xavier Nassif