Patents by Inventor Ikue HARATA

Ikue HARATA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR PRODUCING MESENCHYMAL STEM CELLS FROM LIVING BODY-DERIVED CELL SAMPLE CONTAINING MESENCHYMAL STEM CELLS
    Publication number: 20220177848
    Abstract: Mesenchymal stem cells may be efficiently obtained from a biological cell sample containing mesenchymal stem cells by: (1) culturing the biological cell sample containing mesenchymal stem cells in a serum-free medium in the presence of vitronectin or a partial peptide thereof capable of adhering mesenchymal stem cells, and (2) collecting a cell aggregate of the mesenchymal stem cells.
    Type: Application
    Filed: February 25, 2022
    Publication date: June 9, 2022
    Applicant: AJINOMOTO CO., INC.
    Inventors: Ikue HARATA, Eri HARADA, Kazuma TAKAHASHI, Fumie HONKAWA
  • Culture medium for mesenchymal stem cells
    Patent number: 10947508
    Abstract: Mesenchymal stem cells may be culture for a long period, without using any special apparatus, equipment and the like, in a medium in which seven kinds of nonessential amino acids of glycine, alanine, serine, proline, asparagine, aspartic acid, and glutamic acid are reduced.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: March 16, 2021
    Assignees: AJINOMOTO CO., INC., Kyoto University
    Inventors: Yonghui Jin, Ikue Harata, Sho Senda, Hiroki Ozawa, Tsuyoshi Kobayashi, Junya Toguchida, Makoto Ikeya
  • Culture method for stable proliferation of pluripotent stem cell while maintaining undifferentiated state
    Patent number: 10745669
    Abstract: Cultivating a pluripotent stem cell in a medium comprising at least one member selected from the group consisting of ethanolamine, an ethanolamine analog, and a pharmaceutically acceptable salt thereof, and which is substantially free of ?-mercaptoethanol or contains ?-mercaptoethanol at a concentration of not more than 9 ?M, and the like, is effective for the proliferation of a pluripotent stem cell while maintaining an undifferentiated state.
    Type: Grant
    Filed: July 30, 2015
    Date of Patent: August 18, 2020
    Assignee: AJINOMOTO CO., LTD.
    Inventors: Sho Senda, Tomomi Yoshida, Satoru Okamoto, Yoko Kuriyama, Manabu Kitazawa, Ikue Harata, Nao Sugimoto
  • Culture medium for proliferating stem cell, which contains sulfated compound
    Patent number: 10689622
    Abstract: A medium which comprises a fibroblast growth factor (FGF), and a sulfated compound or a pharmaceutically acceptable salt thereof at a concentration which promotes the growth of a stem cell in the presence of FGF, is useful for culturing stem cells.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: June 23, 2020
    Assignee: AJINOMOTO CO., INC.
    Inventors: Yoko Kuriyama, Nao Sugimoto, Manabu Kitazawa, Satoru Okamoto, Sho Senda, Ikue Harata, Satoru Ohashi
  • Culture method for stable proliferation of pluripotent stem cell while maintaining undifferentiated state
    Patent number: 10662411
    Abstract: Cultivating a pluripotent stem cell in a medium comprising at least one member selected from the group consisting of ethanolamine, an ethanolamine analog, and a pharmaceutically acceptable salt thereof, and which is substantially free of ?-mercaptoethanol or contains ?-mercaptoethanol at a concentration of not more than 9 ?M, and the like, is effective for the proliferation of a pluripotent stem cell while maintaining an undifferentiated state.
    Type: Grant
    Filed: January 8, 2019
    Date of Patent: May 26, 2020
    Assignee: AJINOMOTO CO., INC.
    Inventors: Sho Senda, Tomomi Yoshida, Satoru Okamoto, Yoko Kuriyama, Manabu Kitazawa, Ikue Harata, Nao Sugimoto
  • CULTURE METHOD FOR STABLE PROLIFERATION OF PLURIPOTENT STEM CELL WHILE MAINTAINING UNDIFFERENTIATED STATE
    Publication number: 20190136202
    Abstract: Cultivating a pluripotent stem cell in a medium comprising at least one member selected from the group consisting of ethanolamine, an ethanolamine analog, and a s pharmaceutically acceptable salt thereof, and which is substantially free of ?-mercaptoethanol or contains ?-mercaptoethanol at a concentration of not more than 9 ?M, and the like, is effective for the proliferation of a pluripotent stem cell while maintaining an undifferentiated state.
    Type: Application
    Filed: January 8, 2019
    Publication date: May 9, 2019
    Applicant: AJINOMOTO CO., INC.,
    Inventors: Sho SENDA, Tomomi YOSHIDA, Satoru OKAMOTO, Yoko KURIYAMA, Manabu KITAZAWA, Ikue HARATA, Nao SUGIMOTO
  • MEDIUM FOR NEURAL STEM CELLS ENHANCING NEURAL DIFFERENTIATION ABILITY
    Publication number: 20190024047
    Abstract: Media which are substantially free of one or more amino acids selected from the group consisting of L-glutamine, L-asparagine, and L-aspartic acid are useful for producing a neural stem cell and/or a neural progenitor cell with promoted neuronal differentiation potency.
    Type: Application
    Filed: September 27, 2018
    Publication date: January 24, 2019
    Applicant: AJINOMOTO CO., INC.
    Inventors: Takuya MATSUMOTO, Ikue HARATA, Sho SENDA
  • CULTURE MEDIUM FOR PROLIFERATING STEM CELL, WHICH CONTAINS SULFATED COMPOUND
    Publication number: 20180105798
    Abstract: A medium which comprises a fibroblast growth factor (FGF), and a sulfated compound or a pharmaceutically acceptable salt thereof at a concentration which promotes the growth of a stem cell in the presence of FGF, is useful for culturing stem cells.
    Type: Application
    Filed: December 19, 2017
    Publication date: April 19, 2018
    Applicant: AJINOMOTO CO., INC.
    Inventors: Yoko KURIYAMA, Nao Sugimoto, Manabu Kitazawa, Satoru Okamoto, Sho Senda, Ikue Harata, Satoru Ohashi
  • Culture medium for proliferating stem cell, which contains sulfated compound
    Patent number: 9890359
    Abstract: A medium which comprises a fibroblast growth factor (FGF), and a sulfated compound or a pharmaceutically acceptable salt thereof at a concentration which promotes the growth of a stem cell in the presence of FGF, is useful for culturing stem cells.
    Type: Grant
    Filed: September 26, 2014
    Date of Patent: February 13, 2018
    Assignee: AJINOMOTO CO., INC.
    Inventors: Yoko Kuriyama, Nao Sugimoto, Manabu Kitazawa, Satoru Okamoto, Sho Senda, Ikue Harata, Satoru Ohashi
  • CULTURE MEDIUM FOR PROLIFERATING STEM CELL, WHICH CONTAINS SULFATED COMPOUND
    Publication number: 20150011003
    Abstract: A medium which comprises a fibroblast growth factor (FGF), and a sulfated compound or a pharmaceutically acceptable salt thereof at a concentration which promotes the growth of a stem cell in the presence of FGF, is useful for culturing stem cells.
    Type: Application
    Filed: September 26, 2014
    Publication date: January 8, 2015
    Applicant: AJINOMOTO CO., INC.
    Inventors: Yoko KURIYAMA, Nao SUGIMOTO, Manabu KITAZAWA, Satoru OKAMOTO, Sho SENDA, Ikue HARATA, Satoru OHASHI