Abstract: An embodiment of the present disclosure provides a nozzle device for an FDM-type 3D printer, comprising: a filament supply unit to which filaments for FDM are supplied; a filament nozzle which is positioned under the filament supply unit and melts the filaments supplied from the filament supply unit to output molten filaments; a heater block which is provided around the filament nozzle to melt the filaments inside the filament nozzle; a gas tank; an aerosol generation unit which generates a nanoparticle aerosol; a plasma generation unit which generates plasma; and a plasma nozzle through which the plasma is ejected to the molten filaments, wherein the nanoparticle aerosol generated in the aerosol generation unit flows, together with the gas in the gas tank, to the plasma generation unit through a transfer pipe, and the molten filaments are surface-treated by using the plasma generated in the plasma generation unit and nanoparticles.

Abstract: One embodiment of the present disclosure provides a nozzle device for an FDM-type 3D printer, comprising: a filament supply unit to which a filament for FDM is supplied; a filament nozzle which is positioned on the lower part of the filament supply unit, and which melts the filament received from the filament supply unit so as to output the molten filament; a heater block provided on the circumference of the filament nozzle to melt the filament inside the filament nozzle; a humidifier for generating vapor; and a transfer pipeline, which transfers the vapor of the humidifier to spray same onto the molten filament.

Abstract: The present technique pertains to a method of preparation of a succinylated collagen-fibrinogen hydrogel and a succinylated collagen-fibrinogen hydrogel prepared thereby. The method of preparation of a succinylated collagen-fibrinogen hydrogel according to the present technique can produce a collagen-based bio-substance in a simple process, wherein collagen can be prevented from being entangled and an improvement can be brought about in hydrophilicity, cell growth rate, cell compatibility, and cell diffusion capability, whereby the collagen-based bio-substance exhibits excellent biocompatibility in vivo.

Abstract: The present invention relates to a method for preparing a chitosan succinate having excellent solubility and biocompatibility, and to a succinylated chitosan prepared thereby. The method for preparing a chitosan succinate according to the present invention can prepare a chitosan-based bio-substance having excellent hydrophilicity, cell proliferation rate, cell affinity, and cell proliferation performance through a simple process, thereby having excellent usability in vivo.

Abstract: The present invention relates to an injectable pharmaceutical composition containing keratin for preventing hair loss or stimulating hair growth, wherein the composition is excellent in hair follicle generating and hair growth stimulating effects, and thus can be favorably used as a preventive and therapeutic agent for hair loss or a stimulating agent for hair growth.

Abstract: The present invention relates to a method of manufacturing a nerve electrode in which a conductive ink is inkjet printed on an electrospun polyimide fibrous sheet; and a nerve electrode manufactured by the manufacturing method.

Abstract: The present invention provides a three-dimensional nanofibrous scaffold for tissue regeneration, which is increased in porosity and thickness to enlarge the surface area thereof, thereby enabling cell adhesion at a high density, and a method for fabricating the same. The method for fabricating a three-dimensional nanofibrous scaffold for tissue regeneration includes the steps of: (a) preparing a polymer solution; (b) preparing a nanofiber matrix, in which a plurality of nanofibers is entangled with each other, from the polymer solution prepared in step (a) using electrospinning; and (c) immersing the prepared nanofiber matrix in a solution and subjecting the solution to ultrasonication, thereby increasing the thickness and porosity of the nanofiber matrix.

Abstract: The present invention provides a three-dimensional nanofibrous scaffold for tissue regeneration, which is increased in porosity and thickness to enlarge the surface area thereof, thereby enabling cell adhesion at a high density, and a method for fabricating the same. The method for fabricating a three-dimensional nanofibrous scaffold for tissue regeneration includes the steps of: (a) preparing a polymer solution; (b) preparing a nanofiber matrix, in which a plurality of nanofibers is entangled with each other, from the polymer solution prepared in step (a) using electrospinning; and (c) immersing the prepared nanofiber matrix in a solution and subjecting the solution to ultrasonication, thereby increasing the thickness and porosity of the nanofiber matrix.

Abstract: Disclosed is a biocompatible medical material and porous scaffold for use in tissue engineering, made from a biodegradable glycolide/?-caprolactone copolymer having a repeat unit of wherein x and y are integers greater than or equal to 18, the copolymer has an average molecular weight of about 10,000 daltons or more, and the molar ratio of glycolide: ?-caprolactone in the copolymer is about 4.0:6.0 to 6.0:4.0.

Abstract: Disclosed is a biocompatible medical material and porous scaffold for use in tissue engineering, made from a biodegradable glycolide/&egr;-caprolactone copolymer. The medical material and porous scaffold have excellent mechanical properties such as flexibility and elasticity, and appropriate hydrolytic properties. Due to its superior mechanical properties including elasticity, flexibility and appropriate biodegradation time, it can be used effectively as a porous scaffold for tissue cell culture reproduction such as for artificial skin, blood vessels, dental matrix and wound coverings.