Patents by Inventor Ilan Spector

Ilan Spector has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biological applications of alkaloids derived from the tunicate Eudistoma sp.
    Patent number: 5432172
    Abstract: Biological applications of synthetic and natural alkaloids derived from the tunicate Eudistoma sp. are disclosed. A method regulating cell growth includes contacting one or more cells with an effective concentration of a compound for regulating cell growth. These compounds include: Segoline A, Segoline B, Isosegoline A, Norosegoline, Debromoshermilamine, Eilatin, 4-methylpyrido[2,3,4-kl]acridine, pyrido[2,3,4-kl]acridine, 1-acetyl-2,6-dimethylpyrido[2,3,4-kl]acridine, and derivatives and combinations of these compounds. An effective concentration range for using these compounds can range from approximately 0.1 .mu.M to 100 .mu.M. The effective concentration range for Eilatin, the most potent of these compounds is from 0.01 .mu.M to 0.99 .mu.M, and the effective concentration range for the other compounds of the present invention is from about 1.0 .mu.M to 100 .mu.M.
    Type: Grant
    Filed: March 9, 1993
    Date of Patent: July 11, 1995
    Assignee: The Research Foundation of State University of New York
    Inventors: Ilan Spector, Nava R. Shochet, Yoel Kashman, Amira Rudi, Gary Gellerman
  • Biological applications of alkaloids derived from the tunicate Eudistoma sp.
    Patent number: 5278168
    Abstract: Biological applications of synthetic and natural alkaloids derived from the tunicate Eudistoma sp. are disclosed. A method regulating cell growth includes contacting one or more cells with an effective concentration of a compound for regulating cell growth. These compounds include: Segoline A, Segoline B, Isosegoline A, Norosegoline, Debromoshermilamine, Eilatin, 4-methylpyrido[2,3,4-kl] acridine, pyrido[2,3,4-kl]acridine, 1-acetyl-2,6-dimethylpyrido[2,3,4-kl]acridine, and derivatives and combinations of these compounds. An effective concentration range for using these compounds can range from approximately 0.1 .mu.M to 100 .mu.M. The effective concentration range for Eilatin, the most potent of these compounds is from 0.01 .mu.M to 0.99 .mu.M, and the effective concentration range for the other compounds of the present invention is from about 1.0 .mu.M to 100 .mu.M.
    Type: Grant
    Filed: August 3, 1992
    Date of Patent: January 11, 1994
    Assignee: The Research Foundation of State Univeristy of New York
    Inventors: Ilan Spector, Nava R. Shochet, Yoel Kashman, Amira Rudi
  • New compounds for the study and treatment of microfilament organization in cells
    Patent number: 4857538
    Abstract: A compound, and composition including same, for effecting irreversible change in cell morphology having the following structures: ##STR1## wherein R is --(CH.sub.2).sub.n ZH in which n=1, 2, 3 and 4 and Z is O, S, or NH, and ##STR2## wherein R.sub.1 and R.sub.2 can be --OH, alkyl and acyl.
    Type: Grant
    Filed: November 30, 1987
    Date of Patent: August 15, 1989
    Assignee: The Research Foundation of State University of New York
    Inventors: Yoel Kashman, Ilan Spector, Shmuel Carmely, Dina Blasberger