Patents by Inventor Ilona Fleischhauer

Ilona Fleischhauer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Salts of azelastine having improved solubility effective at treating psoriasis and providing a cytoprotective effect
    Patent number: 6017909
    Abstract: Salts of azelastine with acetic acid, gluconic acid, lactic acid or malic acid.
    Type: Grant
    Filed: August 20, 1998
    Date of Patent: January 25, 2000
    Assignee: Asta Pharma AG
    Inventors: Helmut Hettche, Reinhard Muckenschnabel, Gerhard Scheffler, Ilona Fleischhauer, Wolfgang Morick
  • Salts of azelastine having improved solubility useful at providing a cytoprotective effect
    Patent number: 5998403
    Abstract: The present invention relates to salts of azelastine having improved solubility in water. The salts of the present invention are prepared by reacting azelastine with acetic acid, gluconic acid, lactic acid, or malic acid. The azelastine salts are effective in providing a cytoprotective effect.
    Type: Grant
    Filed: July 28, 1998
    Date of Patent: December 7, 1999
    Assignee: Asta Pharma Aktiengesellschaft
    Inventors: Helmut Hettche, Reinhard Muckenschnabel, Gerhard Scheffler, Ilona Fleischhauer, Wolfgang Morick
  • N-benzylindole and benzopyrazole derivatives with anti-asthmatic, anti-allergic, anti-inflammatory and immunemodulating effect
    Patent number: 5965582
    Abstract: The N-benzylindole- and benzopyrazole derivatives of the general formula 1 ##STR1## possess anti-asthmatic, anti-allergic, anti-inflammatory and immunomodulating effect and are suitable for the preparation of medicaments.
    Type: Grant
    Filed: May 12, 1997
    Date of Patent: October 12, 1999
    Assignee: ASTA Medica Aktiengesellschaft
    Inventors: Guillaume Lebaut, Fabienne Fouchard, Bernhard Kutscher, Peter Emig, Ilona Fleischhauer, Jurgen Schmidt, Stefan Szelenyi
  • Salts of azelastine having improved solubility
    Patent number: 5859003
    Abstract: The present invention relates to salts of azelastine having improved solubility in water. The salts of the present invention are prepared by reacting azelastine with acetic acid, gluconic acid, lactic acid or malic acid. A pharmaceutical composition may be prepared containing an azelastine salt and a pharmaceutically-acceptable carrier or diluent therefor. The pharmaceutical composition is useful in the treatment of allergies, asthma, inflammatory and psoriasis disorders and provides a cytoprotective effect.
    Type: Grant
    Filed: August 2, 1996
    Date of Patent: January 12, 1999
    Assignee: Asta Pharma Aktiengesellschaft
    Inventors: Helmut Hettche, Reinhard Muckenschnabel, Gerhard Scheffler, Ilona Fleischhauer, Wolfgang Morick
  • 1,3,5-tribsubstituted indazole derivatives, processes for preparing, and for pharmacological treatment therewith
    Patent number: 5776932
    Abstract: 1,3,5-trisubstituted indazole derivatives of the formula ##STR1## wherein R1 is H, (b) a C.sub.1-6 straight or branched, substituted or unsubstituted alkyl residue, (c) a C.sub.3-7 cycloalkyl residue, (d) an unsustituted or substituted phenyl, naphthyl, anthranyl, or fluorenyl residue, (e) a quinolin-2-ylmethoxy, or pyridin-2-ylmethoxy residue; X is O, or a --NH, --NH--(C.dbd.O)--NH--, --NH--(C.dbd.O)--O--, --NH--(C.dbd.O)--, or --NH--CH.sub.2 --(C.dbd.O)-- residue; Y is O, or S; R.sub.2 is H; Z is a SO, SO.sub.2, --(CH.sub.2).sub.p --, --(CH.sub.2).sub.p --O--, --O--(CH.sub.2).sub.p --, --(CH.sub.2).sub.p --(C.dbd.O)--, --(C.dbd.O)--(CH.sub.2).sub.p --, --(CH.sub.2).sub.p --(C.dbd.O)--NH--, --NH--(C.dbd.O)--(CH.sub.2).sub.p --, --(CH.sub.2).sub.p --CHOH--, --CHOH--(CH.sub.2).sub.p --, --(CH.sub.2).sub.p --CH.dbd.CH--, or --CH.dbd.CH--(CH.sub.2).sub.
    Type: Grant
    Filed: March 20, 1997
    Date of Patent: July 7, 1998
    Assignee: Arzneimittelwerk Dresden G.m.b.H.
    Inventors: Rudolf Schindler, Ilona Fleischhauer, Istvan Szelenyi
  • Phthalazinone derivatives that modulate multi-drug resistance
    Patent number: 5556856
    Abstract: Phthalazinone derivatives and their optical isomers are used as medications to combat heart rhythm disturbances, to combat pain and to break through multi-drug resistance.
    Type: Grant
    Filed: April 4, 1995
    Date of Patent: September 17, 1996
    Assignee: Asta Medica Aktiengesellschaft
    Inventors: Jurgen Engel, Bernhard Kutscher, Ilona Fleischhauer, Stefan Szelenyi, Peter Metzenauer, Ulrich Werner
  • Aminocarboxylic acid derivatives having antiallergic/antiasthmatic effect and a process for their preparation
    Patent number: 5464838
    Abstract: 6-amino carboxylic acid derivatives having antiasthmatic and antiallergic properties which can be used for the preparation of medicaments. The compounds have the formula: ##STR1## wherein R.sub.1 and R.sub.2 represent hydrogen, a straight-chain or branched alkyl radical with 1-6 carbon atoms, benzyl or phenylethyl, R.sub.3 represents hydrogen, a straight-chain or branched alkyl radical with 1-6 carbon atoms or benzyl, X represents hydrogen, halogen, C.sub.1 -C.sub.6 -alkyl or C.sub.1 -C.sub.6 -alkoxy, Y.sub.1 and Y.sub.2 represent hydrogen, halogen, C.sub.1 -C.sub.6 -alkyl or C.sub.1 -C.sub.6 -alkoxy, where m, n and o can assume the values from 0-4.
    Type: Grant
    Filed: March 4, 1993
    Date of Patent: November 7, 1995
    Assignee: Asta Medica Aktiengesellschaft
    Inventors: Bernhard Kutscher, Georg Niebch, Ilona Fleischhauer, Jurgen Engel, Ute Achterrath-Tuckermann, Stefan Szelenyi
  • Phthalazines containing an aromatic ether or thioether group in the 1-position
    Patent number: 5354750
    Abstract: Pharmacologically active compounds of the General Formula ##STR1## where X is oxygen or sulphur and the radical R represents a quinuclidyl radical, an C.sub.1 -C.sub.6 -alkyl radical, a phenyl radical, a pyridyl radical, a phenyl or pyridyl radical substituted by the radicals R.sub.1, R.sub.2, and/or R.sub.3, a C.sub.1 -C.sub.6 -alkyl radical substituted by pyridyl or alkylpyridyl or a C.sub.1 -C.sub.6 -alkyl radical substituted by phenyl, where each phenyl radical may also be substituted by the radicals R.sub.1, R.sub.2 and/or R.sub.3 and the radicals R.sub.1, R.sub.2 and R.sub.3 are the same or different and represent hydrogen, halogen, trihalogenmethyl, C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.6 -alkoxy, carboxy, Carb-C.sub.1 -C.sub.6 -alkoxy, amino, C.sub.1 -C.sub.6 -alkylamino, C.sub.1 -C.sub.6 -dialkylamino, C.sub.1 -C.sub.6 -trialkylamino, C.sub.2 -C.sub.6 -alkanoylamino, or C.sub.2 -C.sub.
    Type: Grant
    Filed: October 20, 1992
    Date of Patent: October 11, 1994
    Assignee: Asta Medica Aktiengesellschaft
    Inventors: Gerhard Scheffler, Ilona Fleischhauer, Bernhard Kutscher, Jurgen Engel, Stefan Szelenyi, Ulrich Werner
  • Method of treating inflammatory disorders and psoriasis with salts of azelastine
    Patent number: 5086050
    Abstract: Salts of azelastine with acetic acid, gluconic acid, lactic acid or malic acid.
    Type: Grant
    Filed: February 8, 1991
    Date of Patent: February 4, 1992
    Assignee: Asta Pharma AG
    Inventors: Helmut Hettche, Reinhard Muckenschnabel, Gerhard Scheffler, Ilona Fleischhauer, Wolfgang Morick