Abstract: A system and device for intelligent bladder irrigation, including an irrigation sensor structured to detect the presence of blood in an effluent liquid exiting a bladder during irrigation, a discrepancy mechanism structured to measure a difference between an inflow of an irrigant to a patient's bladder and an outflow of the effluent from the patient's bladder, and a flow varying mechanism for adjusting the inflow rate of the irrigant. The system also includes a control device structured to receive data from the irrigation sensor and the flow discrepancy mechanism, and generate a control signal in response.