Patents by Inventor Imran R. Malik

Imran R. Malik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11959856
    Abstract: Methods and algorithms for a multiplexed single detection channel amplification process and quantification of generated amplicons is presented. Various mathematical approaches for quantifying and verifying the amplicons in a reaction are presented. Usage of such methods and approaches allow upgrading of existing single and multiple channel instruments for further multiplexing capabilities.
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: April 16, 2024
    Assignee: California Institute of Technology
    Inventors: Imran R. Malik, Xiomara Linnette Madero, Erika F. Garcia, Sheel Mukesh Shah, Axel Scherer
  • Publication number: 20180052110
    Abstract: Methods and algorithms for a multiplexed single detection channel amplification process and quantification of generated amplicons is presented. Various mathematical approaches for quantifying and verifying the amplicons in a reaction are presented. Usage of such methods and approaches allow upgrading of existing single and multiple channel instruments for further multiplexing capabilities.
    Type: Application
    Filed: September 11, 2017
    Publication date: February 22, 2018
    Inventors: Imran R. MALIK, Xiomara Linnette MADERO, Erika F. GARCIA, Sheel Mukesh SHAH, Axel SCHERER
  • Patent number: 9791372
    Abstract: Methods and algorithms for a multiplexed single detection channel amplification process and quantification of generated amplicons is presented. Various mathematical approaches for quantifying and verifying the amplicons in a reaction are presented. Usage of such methods and approaches allow upgrading of existing single and multiple channel instruments for further multiplexing capabilities.
    Type: Grant
    Filed: August 2, 2013
    Date of Patent: October 17, 2017
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Imran R. Malik, Xiomara Linnette Madero, Erika F. Garcia, Sheel Mukesh Shah, Axel Scherer
  • Patent number: 9561505
    Abstract: Devices and system for preparing samples are described. Such devices can comprise fluidic chambers, reservoirs, and movable structures for controlling the movement of samples. The device can also comprise functional elements for performing specific operations.
    Type: Grant
    Filed: September 11, 2014
    Date of Patent: February 7, 2017
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Imran R. Malik, Axel Scherer
  • Patent number: 9518291
    Abstract: Methods and devices for biological sample preparation and analysis are disclosed. A device may have a linear or circular arrangement of containers, with a connecting structure such as a bar or disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. Different functional elements, such as grinders or mixers, may be attached to the containers. The device may have a reaction cartridge with a reaction chamber to perform techniques such as polymerase chain reaction.
    Type: Grant
    Filed: November 1, 2013
    Date of Patent: December 13, 2016
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Imran R. Malik, Erika F. Garcia, Xiomara Linnette Madero, Axel Scherer
  • Patent number: 9416343
    Abstract: Methods and devices for biological sample preparation and analysis are disclosed. A device may have a linear or circular arrangement of containers, with a connecting structure such as a bar or disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. Different functional elements, such as grinders or mixers, may be attached to the containers.
    Type: Grant
    Filed: November 1, 2013
    Date of Patent: August 16, 2016
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Imran R. Malik, Axel Scherer, Erika F. Garcia, Xiomara L. Madero
  • Publication number: 20160151782
    Abstract: A fluidic device including a body having a surface and one or more channels located in the body. Recesses are defined on said surface. The one or more channels can have respective boundaries. A layer of adhesive including one or more panel-shaped pieces having a pattern based on the pattern of boundaries of the channels can be formed and applied on the surface of the body. It is further controlled that the layer of adhesive has respective boundaries surrounding the boundaries of the one or more channels.
    Type: Application
    Filed: December 8, 2015
    Publication date: June 2, 2016
    Inventors: Imran R. MALIK, Axel SCHERER
  • Patent number: 9284520
    Abstract: Methods and devices for biological sample preparation and analysis are disclosed. A device may have a linear or circular arrangement of containers, with a connecting structure such as a bar or disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. Different functional elements, such as grinders or mixers, may be attached to the containers.
    Type: Grant
    Filed: November 1, 2013
    Date of Patent: March 15, 2016
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Imran R. Malik, Erika F. Garcia, Xiomara Linnette Madero, Axel Scherer
  • Patent number: 9233369
    Abstract: A method of fabricating a fluidic device comprises providing a fluidic device including a body having a surface and one or more channels located in the body. Recesses are defined on said surface. The one or more channels can have respective boundaries. A layer of adhesive including one or more panel-shaped pieces having a pattern based on the pattern of boundaries of the channels can be formed and applied on the surface of the body. It is further controlled that the layer of adhesive has respective boundaries surrounding the boundaries of the one or more channels.
    Type: Grant
    Filed: December 23, 2011
    Date of Patent: January 12, 2016
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Imran R. Malik, Axel Scherer
  • Publication number: 20150321195
    Abstract: Temperature control devices and methods are described. The described temperature control devices and methods comprise optical emission and detection assemblies and can be used in PCR and qPCR applications.
    Type: Application
    Filed: April 27, 2015
    Publication date: November 12, 2015
    Inventors: Imran R. MALIK, Axel SCHERER
  • Patent number: 9090890
    Abstract: Methods and devices for biological sample preparation and analysis are disclosed. A device may have a linear or circular arrangement of containers, with a connecting structure such as a bar or disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. Different functional elements, such as grinders or mixers, may be attached to the containers.
    Type: Grant
    Filed: November 1, 2013
    Date of Patent: July 28, 2015
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Imran R Malik, Erika F Garcia, Xiomara Linnette Madero, Axel Scherer
  • Patent number: 9090891
    Abstract: Methods and devices for biological sample preparation and analysis are disclosed. A device may have a circular arrangement of containers, with a connecting structure such as a disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. The device may be pen-shaped and have a sample drawing needle connected to the containers.
    Type: Grant
    Filed: November 1, 2013
    Date of Patent: July 28, 2015
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Xiomara Linnette Madero, Imran R Malik, Erika F Garcia, Axel Scherer
  • Patent number: 9057568
    Abstract: Temperature control devices and methods are described. The described temperature control devices and methods comprise optical emission and detection assemblies and can be used in PCR and qPCR applications.
    Type: Grant
    Filed: December 15, 2009
    Date of Patent: June 16, 2015
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Imran R. Malik, Axel Scherer
  • Patent number: 8980550
    Abstract: Methods for measuring and analyzing biological or chemical samples using consumer electronic devices and systems are described. Moreover, an accessory to enable using devices such as cell phones and smartphones with fluidic illumination chambers are described.
    Type: Grant
    Filed: January 19, 2011
    Date of Patent: March 17, 2015
    Assignee: California Institute of Technology
    Inventors: Imran R. Malik, Axel Scherer
  • Patent number: 8968585
    Abstract: Methods to fabricate reaction cartridges for biological sample preparation and analysis are disclosed. A cartridge may have a reaction chamber and openings to allow fluids to enter the chamber. The cartridge may also have handles to facilitate its use. Such cartridges may be used for polymerase chain reaction.
    Type: Grant
    Filed: November 1, 2013
    Date of Patent: March 3, 2015
    Assignee: California Institute of Technology
    Inventors: Imran R. Malik, Axel Scherer, Erika F. Garcia, Xiomara L. Madero
  • Publication number: 20150024481
    Abstract: Devices and system for preparing samples are described. Such devices can comprise fluidic chambers, reservoirs, and movable structures for controlling the movement of samples. The device can also comprise functional elements for performing specific operations.
    Type: Application
    Filed: September 11, 2014
    Publication date: January 22, 2015
    Inventors: Imran R. MALIK, Axel SCHERER
  • Patent number: 8883088
    Abstract: Devices and system for preparing samples are described. Such devices can comprise fluidic chambers, reservoirs, and movable structures for controlling the movement of samples. The device can also comprise functional elements for performing specific operations.
    Type: Grant
    Filed: February 28, 2012
    Date of Patent: November 11, 2014
    Assignee: California Institute of Technology
    Inventors: Imran R. Malik, Axel Scherer
  • Patent number: 8873055
    Abstract: Structures and methods are described for optical detection of physical, chemical and/or biological samples. An optical detection structure may include a LED source, multiple filters and single or multiple sample areas. A detector may be used to record a fluorescence signal. The sample area may allow the introduction of removable cartridges.
    Type: Grant
    Filed: July 22, 2013
    Date of Patent: October 28, 2014
    Assignee: California Institute of Technology
    Inventors: Imran R. Malik, Xiomara L. Madero, Erika F. Garcia, Axel Scherer
  • Publication number: 20140127796
    Abstract: Methods and devices for biological sample preparation and analysis are disclosed. A device may have a linear or circular arrangement of containers, with a connecting structure such as a bar or disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. Different functional elements, such as grinders or mixers, may be attached to the containers.
    Type: Application
    Filed: November 1, 2013
    Publication date: May 8, 2014
    Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Imran R. MALIK, Axel SCHERER, Erika F. GARCIA, Xiomara L. MADERO
  • Publication number: 20140127790
    Abstract: Methods and devices for biological sample preparation and analysis are disclosed. A device may have a linear or circular arrangement of containers, with a connecting structure such as a bar or disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. Different functional elements, such as grinders or mixers, may be attached to the containers.
    Type: Application
    Filed: November 1, 2013
    Publication date: May 8, 2014
    Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Imran R. MALIK, Erika F. GARCIA, Xiomara Linnette MADERO, Axel SCHERER