Abstract: There is provided a method of manufacturing a zirconia block for an artificial tooth having a color gradient. The method includes: preparing colored zirconia-based powder and white zirconia-based powder; preparing a plurality of raw materials in which the colored zirconia-based powder and the white zirconia-based powder are mixed in different weight ratios by mixing the colored zirconia-based powder and the white zirconia-based powder while changing a mixing ratio in order to express a desired color gradient; sequentially injecting the plurality of raw materials into a compression mold or a mold frame to mold in increasing or decreasing order of content of the colored zirconia-based powder of the raw material; and calcining a molding result. According to the present invention, it is possible to express aesthetics of a natural tooth by implementing a color gradient of the natural tooth in the zirconia block itself without using porcelain powder or a liquid color set.

Abstract: There is provided a method of manufacturing a zirconia block for an artificial tooth having a color gradient. The method includes: preparing colored zirconia-based powder and white zirconia-based powder; preparing a plurality of raw materials in which the colored zirconia-based powder and the white zirconia-based powder are mixed in different weight ratios by mixing the colored zirconia-based powder and the white zirconia-based powder while changing a mixing ratio in order to express a desired color gradient; sequentially injecting the plurality of raw materials into a compression mold or a mold frame to mold in increasing or decreasing order of content of the colored zirconia-based powder of the raw material; and calcining a molding result. According to the present invention, it is possible to express aesthetics of a natural tooth by implementing a color gradient of the natural tooth in the zirconia block itself without using porcelain powder or a liquid color set.

Abstract: Disclosed herein is an anticancer composition, comprising obovatol, represented by the following Chemical Formula 1, obovatal, represented by the following Chemical Formula 2, and/or pharmaceutical salts thereof. The composition exhibits the activity of inhibiting the growth of cancer cells and suppressing the expression and activity of matrix metalloproteinases (MMPs), and thus can be useful for the prophylaxis and treatment of cancer as well as for the inhibition of cancer metastasis.

Abstract: The present invention is related to new 2-oxo-cyclic compound the process for preparing them and a pharmaceutical composition comprising the same. The present invention provides a pharmaceutical composition for preventing and treating the inflammatory disease comprising the pain or inflammation caused by rheumatic disease, for example, rheumatoid arthritis, spondyloarthopathies, gout, osteoarthritis, systemic lupus erythematosus and juvenile arthritis, and inflammatory syndrome for example, from myositis, gingivitis, synovitis, ankylosing spondylitis, burstitis, burns and scar, inflammatory Crohn's disease, Types I diabetes. therefore, it can be used as the therapeutics for treating and preventing inflammatory diseases.

Abstract: The present invention is related to new 2-oxo-cyclic compound, the process for preparing them and a pharmaceutical composition comprising the same. The present invention provides a pharmaceutical composition for preventing and treating the inflammatory disease comprising the pain or inflammation caused by rheumatic disease, for example, rheumatoid arthritis, spondyloarthopathies, gout, osteoarthritis, systemic lupus erythematosus and juvenile arthritis, and inflammatory syndrome for example, from myositis, gingivitis, synovitis, ankylosing spondylitis, burstitis, burns and scar, inflammatory Crohn's disease, Types I diabetes. therefore, it can be used as the therapeutics for treating and preventing inflammatory diseases.

Abstract: Disclosed is a method for reconstructing an X-ray CT (computerized tomography) image. The method includes acquiring projection data by means of irradiation of X-rays on a target object at a position close to an X-ray generator such that a portion of the target object including a local region of interest exists within a range of irradiation angles of X-rays, calculating virtual projection data on the assumption that the X-rays are irradiated on the entire target object at the close position, based on projection data acquired through irradiation of the X-rays on the entire target object at a position where the entire target object exists within the range of irradiation angles of X-rays, combining the virtual projection data on the entire target object except data on the local region of interest with the projection data acquired at the position close to the X-ray generator, and reconstructing the combined projection data.

Abstract: Disclosed herein is an anticancer composition, comprising obovatol, represented by the following Chemical Formula 1, obovatal, represented by the following Chemical Formula 2, and/or pharmaceutical salts thereof. The composition exhibits the activity of inhibiting the growth of cancer cells and suppressing the expression and activity of matrix metalloproteinases (MMPs), and thus can be useful for the prophylaxis and treatment of cancer as well as for the inhibition of cancer metastasis.

Abstract: Disclosed is a method for reconstructing an X-ray CT (computerized tomography) image. The method includes acquiring projection data by means of irradiation of X-rays on a target object at a position close to an X-ray generator such that a portion of the target object including a local region of interest exists within a range of irradiation angles of X-rays, calculating virtual projection data on the assumption that the X-rays are irradiated on the entire target object at the close position, based on projection data acquired through irradiation of the X-rays on the entire target object at a position where the entire target object exists within the range of irradiation angles of X-rays, combining the virtual projection data on the entire target object except data on the local region of interest with the projection data acquired at the position close to the X-ray generator, and reconstructing the combined projection data.

Abstract: Disclosed is a pharmaceutical composition for treating and preventing cancer, comprising a Cinnamoni Cortex extract and a Zizyphi Fructus extract. The pharmaceutical composition has effects of inducing apoptosis of cancer cells and inhibiting metastasis of cancer cells, as well as having a synergistic effect in inhibiting the growth of cancer cells compared to the separate use of the two extracts. Also, because the two extracts are extracted from natural origins, the pharmaceutical composition has no toxicity and is thus able to be used as a safe anticancer agent having excellent therapeutic efficacy. Further, the pharmaceutical composition is capable of being used as a functional food for preventing and treating cancer.

Abstract: Disclosed herein is an anticancer composition, comprising obovatol, represented by the following Chemical Formula 1, obovatal, represented by the following Chemical Formula 2, and/or pharmaceutical salts thereof. The composition exhibits the activity of inhibiting the growth of cancer cells and suppressing the expression and activity of matrix metalloproteinases (MMPs), and thus can be useful for the prophylaxis and treatment of cancer as well as for the inhibition of cancer metastasis.