Patents by Inventor Indra B. Nigam

Indra B. Nigam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8880162
    Abstract: The present disclosure generally relates to a method, a device, and a computer-readable storage medium for detecting heart beats from cardiac signals whose quality, expressed in terms of signal amplitude and signal-to-noise ratio, varies dynamically in time. Hence, a method, a device, and a computer-readable storage medium for detecting electrical signals originating from a human or animal heart is proposed. The method includes the following steps: a) identifying an initial indication of the event in at least one of the signal channels, b) deciding whether or not the identified initial indication confirms the event depending on the quality of the signal channels in which initial indications are identified; and c) determining a point-of-detection for the event depending on the quality of the signal channels and depending from the shape of the signal.
    Type: Grant
    Filed: November 8, 2010
    Date of Patent: November 4, 2014
    Assignee: BIOTRONIK CRM Patent AG
    Inventor: Indra B. Nigam
  • Patent number: 8190247
    Abstract: Method for detecting cardiac events, e.g., Atrial Fibrillation (AF) or termination of AF. Based on analysis of the instability observed in heart rate, caused by irregular conduction from the atrium during AF. Change in heart interval is monitored on beat-to-beat basis to recognize instability that indicates presence of AF or Atrial Flutter. A packet of a number of consecutive intervals is evaluated, whether the length of an interval is stable compared with the length of the preceding interval, or whether the length of the subsequent interval has changed. After detection of an instability, instability counter is incremented. The result of the stability test for a packet of intervals is represented by the value of the instability counter. Depending upon whether or not an AF already declared, (indicated by AF status flag), different “X-out-of-Y” criterion are applied. AF status flag set/cleared when declaring AF/termination of AF.
    Type: Grant
    Filed: October 14, 2009
    Date of Patent: May 29, 2012
    Assignee: Biotronik CRM Patent AG
    Inventors: Indra B. Nigam, Dirk Muessig
  • Patent number: 8024031
    Abstract: Device for classifying tachyarrhythmia that obtains pre-defined values, monitors atrial intervals and compares lengths of each interval with pre-defined value IL, stores length of atrial interval if length is shorter than IL, in case X of most recent Y number of atrial intervals have length shorter than IL, evaluates most recent <=N atrial intervals with length <IL and performs test for stored lengths via criteria, classifies atrial tachyarrhythmia as stable if all tested lengths pass >=1 criteria, and controls a cardiac device depending on the classification. Atrial intervals are first evaluated by using the “X-out-of-Y” criterion and subsequently checked for stability after an atrial tachyarrhythmia is detected using “X-out-of-Y” criterion. For stability check, only intervals found shorter than the interval limit are used. Check is based on interval-to-interval comparison rather than as generally practiced, comparisons of individual intervals with the minimum or average of all intervals.
    Type: Grant
    Filed: October 20, 2008
    Date of Patent: September 20, 2011
    Assignee: Biotronik CRM Patent AG
    Inventors: Indra B. Nigam, Dirk Muessig, Hannes Kraetschmer
  • Publication number: 20110125043
    Abstract: The present disclosure generally relates to a method, a device, and a computer-readable storage medium for detecting heart beats from cardiac signals whose quality, expressed in terms of signal amplitude and signal-to-noise ratio, varies dynamically in time. Hence, a method, a device, and a computer-readable storage medium for detecting electrical signals originating from a human or animal heart is proposed. The method includes the following steps: a) identifying an initial indication of the event in at least one of the signal channels, b) deciding whether or not the identified initial indication confirms the event depending on the quality of the signal channels in which initial indications are identified; and c) determining a point-of-detection for the event depending on the quality of the signal channels and depending from the shape of the signal.
    Type: Application
    Filed: November 8, 2010
    Publication date: May 26, 2011
    Applicant: BIOTRONIK CRM Patent AG
    Inventor: Indra B. Nigam
  • Publication number: 20100100143
    Abstract: Device for classifying tachyarrhythmia that obtains pre-defined values, monitors atrial intervals and compares lengths of each interval with pre-defined value IL, stores length of atrial interval if length is shorter than IL, in case X of most recent Y number of atrial intervals have length shorter than IL, evaluates most recent <=N atrial intervals with length<IL and performs test for stored lengths via criteria, classifies atrial tachyarrhythmia as stable if all tested lengths pass >=1 criteria, and controls a cardiac device depending on the classification. Atrial intervals are first evaluated by using the “X-out-of-Y” criterion and subsequently checked for stability after an atrial tachyarrhythmia is detected using “X-out-of-Y” criterion. For stability check, only intervals found shorter than the interval limit are used. Check is based on interval-to-interval comparison rather than as generally practiced, comparisons of individual intervals with the minimum or average of all intervals.
    Type: Application
    Filed: October 20, 2008
    Publication date: April 22, 2010
    Inventors: Indra B. Nigam, Dirk Muessig, Hannes Kraetschmer
  • Publication number: 20100099996
    Abstract: Method for detecting cardiac events, e.g., Atrial Fibrillation (AF) or termination of AF. Based on analysis of the instability observed in heart rate, caused by irregular conduction from the atrium during AF. Change in heart interval is monitored on beat-to-beat basis to recognize instability that indicates presence of AF or Atrial Flutter. A packet of a number of consecutive intervals is evaluated, whether the length of an interval is stable compared with the length of the preceding interval, or whether the length of the subsequent interval has changed. After detection of an instability, instability counter is incremented. The result of the stability test for a packet of intervals is represented by the value of the instability counter. Depending upon whether or not an AF already declared, (indicated by AF status flag), different “X-out-of-Y” criterion are applied. AF status flag set/cleared when declaring AF/termination of AF.
    Type: Application
    Filed: October 14, 2009
    Publication date: April 22, 2010
    Inventors: Indra B. NIGAM, Dirk Muessig
  • Patent number: 7657305
    Abstract: An implantable medical device provides for improved storage of recorded IEGMs. A sensing stage is connected to an electrode for picking up electric potentials from inside a heart, the time course of said electric potentials representing a heart signal, a control unit connected to said sensing stage is adapted to process a sequence of data points that each represent an amplitude or magnitude A of a time-varying signal at equidistant points of time t, wherein end points of data segments are determined by processing of the sequence of data points. The control unit is adapted to identify end points of data segments by processing of the sequence of data points.
    Type: Grant
    Filed: November 27, 2006
    Date of Patent: February 2, 2010
    Assignee: BIOTRONIK CRM Patent AG
    Inventor: Indra B. Nigam
  • Patent number: 7580748
    Abstract: A heart stimulator provides a reliable automatic capture threshold search feature. A stimulation pulse generator is connected to at least a ventricular stimulation electrode for delivering electric stimulation pulses to at least the ventricle of the heart. The stimulation pulses generated have a strength depending on a control signal. A sensing stage is connected to an electrode for picking up electric potentials inside at least said ventricle of a heart and a control unit connected to the sensing stage and to the stimulation pulse generator determines points of time for scheduling stimulation pulses, to trigger the stimulation pulse generator so as to deliver a stimulation pulse when scheduled and to put out control signals for controlling the strength of the stimulation pulse. The control unit is further adapted to perform a capture analysis which may take into account extraordinary events.
    Type: Grant
    Filed: December 7, 2006
    Date of Patent: August 25, 2009
    Assignee: Biotronik CRM Patent AG
    Inventors: Garth Garner, Hannes Kraetschmer, Dirk Muessig, Indra B. Nigam
  • Publication number: 20080147133
    Abstract: An implantable medical device for processing picked-up electric heart signals and to a method of controlling sensitivity of a sensing stage of the device. The sensing stage is connected to an electrode picking up electric potentials inside the heart, has an adjustable sensitivity and generates a detect signal indicating detection of a sense event if the time course of the picked-up signal exceeds the detection threshold. A peak amplitude detector determines a peak amplitude. A peak amplitude comparator determines whether the peak amplitude exceeds a predetermined peak amplitude threshold value, and a control unit adapts the detection threshold by adjusting the sensing stage's sensitivity. The control unit sets the detection threshold for a first detection period to a high value, subsequently lowers the detection threshold stepwise for further detection periods.
    Type: Application
    Filed: December 15, 2006
    Publication date: June 19, 2008
    Inventors: Garth GARNER, Christian Kreidler, Indra B. Nigam
  • Publication number: 20080140146
    Abstract: A heart stimulator provides a reliable automatic capture threshold search feature. A stimulation pulse generator is connected to at least a ventricular stimulation electrode for delivering electric stimulation pulses to at least the ventricle of the heart. The stimulation pulses generated have a strength depending on a control signal. A sensing stage is connected to an electrode for picking up electric potentials inside at least said ventricle of a heart and a control unit connected to the sensing stage and to the stimulation pulse generator determines points of time for scheduling stimulation pulses, to trigger the stimulation pulse generator so as to deliver a stimulation pulse when scheduled and to put out control signals for controlling the strength of the stimulation pulse. The control unit is further adapted to perform a capture analysis which may take into account extraordinary events.
    Type: Application
    Filed: December 7, 2006
    Publication date: June 12, 2008
    Inventors: Garth GARNER, Hannes Kraetschmer, Dirk Muessig, Indra B. Nigam
  • Publication number: 20080125665
    Abstract: An implantable medical device provides for improved storage of recorded IEGMs. A sensing stage is connected to an electrode for picking up electric potentials from inside a heart, the time course of said electric potentials representing a heart signal, a control unit connected to said sensing stage is adapted to process a sequence of data points that each represent an amplitude or magnitude A of a time-varying signal at equidistant points of time t, wherein end points of data segments are determined by processing of the sequence of data points. The control unit is adapted to identify end points of data segments by processing of the sequence of data points.
    Type: Application
    Filed: November 27, 2006
    Publication date: May 29, 2008
    Inventor: Indra B. Nigam
  • Patent number: 6934582
    Abstract: Apparatus for treating fibrillation of at least one chamber of a heart comprising a fibrillation detector for detecting a fibrillation, a defibrillator for defibrillating the chamber of the heart, wherein the defibrillator is connected to the fibrillation detector and is adapted to effect defibrillation subsequently to a time interval after detection of the fibrillation, a warning device which is connected to the fibrillation detector and which is adapted to delivery a warning signal when a fibrillation has been detected, and a control circuit having a control input actuable by a patient, wherein the control circuit is connected to the defibrillator and is adapted to delay the time of a defibrillation if the control circuit receives a corresponding signal by way of the control input, wherein the apparatus includes a condition detector which is adapted to detect a hemodynamic condition of the heart, and the control circuit is connected to the condition detector and is adapted to prevent a delay in the time of
    Type: Grant
    Filed: December 13, 2001
    Date of Patent: August 23, 2005
    Assignee: Biotronik Mess -und Therapiegeraete GmbH & Co. Ingenieurbuero Berlin
    Inventors: Tran Thong, Indra B. Nigam, Mrigank Shekhar, Max Schaldach, Jr., Max Schaldach
  • Patent number: 6748267
    Abstract: A heart therapy device includes a heart rate detector unit for detecting a heart rate, an evaluation and control unit adaptable to evaluate a measured heart rate and output a therapy control signal, and a therapy unit coupled to the output of the evaluation and control means for realizing at least one therapy having a predetermined therapy. The evaluation and control unit includes a three-area memory for storing heart rate value ranges, a heart rate discriminator for allocating a measured heart rate and outputting a first, second or third discriminator output signal, a stability evaluation unit for outputting a stability output signal and evaluating heart rate stability over a predetermined period of time in response to the output of the second heart rate discriminator output signal, and a logical processing unit for processing the second discriminator output.
    Type: Grant
    Filed: July 25, 2001
    Date of Patent: June 8, 2004
    Assignee: Biotronik Mess-und Therapiegeraete GmbH & Co.
    Inventors: Mrigank Shekhar, Tran Thong, Indra B. Nigam
  • Publication number: 20040059390
    Abstract: An arrangement for treating rhythm disturbances of a heart (H), especially tachycardia and fibrillation, has a device (FD) for detecting the heart rhythm and determining when a fibrillation threshold limit is exceeded and a therapy device or stimulator (IG). The therapy device (IG) is connected to the heart rhythm detecting device (FD), to begin to treat the fibrillation when the fibrillation threshold limit is exceeded. The heart rhythm detecting device determines whether a redetection threshold limit is still exceeded after the therapy device has treated the fibrillation, the redetection threshold limit being lower than the fibrillation threshold limit and higher than a tachycardia threshold limit. The therapy device continues to treat the fibrillation as long as the heart rhythm detector determines that the redection threshold limit is exceeded.
    Type: Application
    Filed: September 18, 2003
    Publication date: March 25, 2004
    Applicant: Biotronik Mess-und Therapiegeraete GmbH & Co. Ingenieurbuero Berlin
    Inventors: Tran Thong, Mrigank Shekhar, Indra B. Nigam
  • Publication number: 20030023272
    Abstract: Heart therapy device, in particular implantable defibrillator, heart pacemaker or combined heart pacemaker, comprising an evaluation and control means for evaluating a measured heart rate, which comprises a three-area memory for storing a first, second and third value range of reference heart rates adjacent to one another with ascending heart rate values, a heart rate discriminator for allocating a measured heart rate to the first, second or third value range, and a stability evaluation means for evaluating the heart rate stability over a predetermined period of time upon detection of a heart rate lying within the second value range.
    Type: Application
    Filed: July 25, 2001
    Publication date: January 30, 2003
    Inventors: Mrigank Shekhar, Tran Thong, Indra B. Nigam
  • Patent number: 6480739
    Abstract: Method for avoiding the detection of a far-field QRS by the atrial detector of a heart pacemaker or ICD while allowing the detection of a true atrial signal to a maximum possible extent; the method comprising generating a Short Atrial Refractory Period (SARP) following an atrial sensed or paced event by means of a SARP timer, blanking of the atrial detector following a ventricular paced event, generating a Post Ventricular Short Atrial Refractory Period (PVSARP) following a ventricular sensed or paced event by means of a PVSARP timer, generating a temporary decrease in the sensivity of an amplifier for the atrial signal for a time period following the elapse of the mentioned PVSARP, and gradually increasing the sensitivity of the amplifier for the atrial signal after said time period.
    Type: Grant
    Filed: March 30, 2001
    Date of Patent: November 12, 2002
    Assignee: Biotronik Mess - und Therapiegeräte GmbH & Co. Ingenieurbüro Berlin
    Inventors: Indra B. Nigam, Andreas Hahn, Andreas Kucher, Mrigank Shekhar
  • Publication number: 20020120300
    Abstract: Apparatus for treating fibrillation of at least one chamber of a heart comprising a fibrillation detector (1) for detecting a fibrillation, a defibrillator (2) for defibrillating the chamber of the heart, wherein the defibrillator is connected to the fibrillation detector (1) and is adapted to effect defibrillation subsequently to a time interval after detection of the fibrillation, a warning device (3) which is connected to the fibrillation detector (1) and which is adapted to delivery a warning signal when a fibrillation has been detected, and a control means (4) having a control input (5) actuable by a patient, wherein the control means is connected to the defibrillator (2) and is adapted to delay the time of a defibrillation if the control means (4) receives a corresponding signal by way of the control input (5), wherein the apparatus includes a condition detector (6) which is adapted to detect a hemodynamic condition of the heart, and the control means (4) is connected to the condition detector (6) and i
    Type: Application
    Filed: December 13, 2001
    Publication date: August 29, 2002
    Applicant: Biotronik Mess- und Therapiegeraete GmbH & Co
    Inventors: Tran Thong, Indra B. Nigam, Mrigank Shekhar, Max Schaldach, Max Schaldach
  • Patent number: 6181966
    Abstract: A heart therapy apparatus (1) with detection means (3, 5, 9) for detecting a physiological parameter that characterizes the state of the heart/circulatory system, with comparison value storage means (17), comparator means (15) for comparing the detected values to the stored values, therapy storage means (23) for storing a plurality of potential therapies, therapy means (25) for selectively realizing one of the potential therapies, with therapy registration means (27) for registering a realized therapy, and therapy selection means (19) for selecting one of the stored therapies and activating the therapy means in dependence on the classification signal and the memory content of the therapy registration means.
    Type: Grant
    Filed: December 28, 1998
    Date of Patent: January 30, 2001
    Assignees: Biotronik Mess- und Therapieger{umlaut over (a)}te GmbH & Co., Ingenieurb{umlaut over (u)}ro
    Inventor: Indra B. Nigam
  • Patent number: 6061592
    Abstract: A device for detecting pathological tachycardia, in particular for use with an implantable device for terminating tachycardias, having a classifican device, responding to at least one electrical signal derived from the heart, which if the classification criterion is met outputs an output signal indicating pathological tachycardia, having a plurality of classification devices for checking various classification criteria within one heart interval or on the basis of the evaluation of preceding heart intervals; a controllable counter that is connected to the outputs of the classification devices via first logic means; means for incrementing the counter state of the counter by a predetermined counting amount each time, if during a heart interval at least one of the primary classification signals appears; means for keeping the counter state constant or decrementing it by a predetermined counting amount, if no primary classification signal appears within the heart interval; and discriminator means, which output the
    Type: Grant
    Filed: May 6, 1998
    Date of Patent: May 9, 2000
    Assignee: Biotronik Mess-und Therapiegeraete GmbH & Co. Ingenieurbuero Berlin
    Inventor: Indra B. Nigam
  • Patent number: 5978700
    Abstract: An apparatus for detecting ventricular tachycardia includes a first and snd calculation unit, each having an input side connected to a ventricle sensor and an atrium sensor, respectively, and to a timer, for calculating the R--R and P--P intervals between respective successive electrical activities in the atrium and in the ventricle. A threshold value memory stores at least one threshold value for the R--R intervals in memory. A first comparator unit compares the R--R intervals with the at least one threshold value. A first and second interval memory store a predetermined number of calculated R--R and P--P intervals, respectively, or mean R--R and mean P--P interval values. A second comparator unit compares the P--P intervals with the R--R intervals. A third and fourth calculation unit, connected to the output of the first and second calculation unit and/or of the first and second interval memory unit, respectively, calculate the change over time between successive P--P and R--R intervals.
    Type: Grant
    Filed: May 6, 1998
    Date of Patent: November 2, 1999
    Assignee: Biotronik Mess-und Therapiegeraete GmbH & Co. Ingenierbuero Berlin
    Inventor: Indra B. Nigam