Abstract: A liquid chromatography (LC) system comprises an LC switching valve comprising a sample input port, aspiration pump port, needle seat port, waste port leading to a waste, LC pump port and an LC column port. A sample aspiration needle is fluidically connected to the sample input port via a sample receiving conduit, an aspiration pump is fluidically connected to the aspiration pump port. The LC system includes a needle seat fluidically connected to the needle seat port via a needle seat conduit, an LC column fluidically connected to the LC column port, and an LC pump fluidically connected to the LC pump port, for injecting the sample into the LC column when the sample aspiration needle is seated into the needle seat and when the LC pump port is fluidically connected to the needle seat port and the sample input port is fluidically connected to the LC column port.

Abstract: The present invention relates to a method for detecting and/or quantifying an analyte in a sample using mass spectrometry. The method of the invention comprises: extracting the analyte from the sample using solid phase extraction (SPE) so as to obtain an SPE extract comprising the analyte, concentrating the analyte, said concentrating comprising evaporating solvent from the SPE-extract; and detecting and/or quantifying the analyte in the sample using mass spectrometry.

Abstract: A transmitter device for a secure communication based on quantum cryptography, the transmitter device comprises a transmitter optical communication module for transmitting light pulses from the transmitter device to a receiver device, and the transmitter optical communication module enables exchange of a quantum key between the transmitter device and the receiver device. The transmitter device comprises transmitter data communication module for exchanging data between the transmitter device and the receiver device, the data is encrypted by the quantum key thereby ensuring a secure communication between the transmitter device and the receiver device. The transmitter device further contains a status display on a front side of the transmitter device for displaying status of the secure communication between the transmitter device and the receiver device.

Abstract: A liquid chromatography (LC) system comprises an LC switching valve comprising a sample input port, aspiration pump port, needle seat port, waste port leading to a waste, LC pump port and an LC column port. A sample aspiration needle is fluidically connected to the sample input port via a sample receiving conduit, an aspiration pump is fluidically connected to the aspiration pump port. The LC system includes a needle seat fluidically connected to the needle seat port via a needle seat conduit, an LC column fluidically connected to the LC column port, and an LC pump fluidically connected to the LC pump port, for injecting the sample into the LC column when the sample aspiration needle is seated into the needle seat and when the LC pump port is fluidically connected to the needle seat port and the sample input port is fluidically connected to the LC column port.

Abstract: The present invention refers to a method for determining peptide fragments of glycated hemoglobin A (HbA1c) molecules by mass spectrometry (MS), a reagent kit, and a clinical diagnostic system adapted for performing the method.

Abstract: The present invention refers to a method for determining intact glycated hemoglobin A (HbA1c) by mass spectrometry (MS), a kit and a diagnostic system adapted for performing the method.

Abstract: A computerized method and apparatus for enumerating one or more amino acid compositions is disclosed that provides one or more processors, a data storage communicably coupled to the one or more processors and a user interface communicably coupled to the one or more processors. The three or more user-specified characteristics are received from the data storage or the user interface. The one or more amino acid compositions are enumerated for all the peptides having a length less than or equal to the maximum length and a mass less than or equal to the mass limit using the one or more processors. The enumerated amino acid compositions are filtered based on the one or more other user-specified characteristics using the one or more processors. The filtered amino acid compositions and the mass of the filtered amino acid compositions are stored in the data storage.