Abstract: The present invention relates to novel Mannose-binding lectin (MBL)-associated serine protease (MASP) inhibitory compounds, as well as analogues and derivatives thereof, to processes for the preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of renal and cardiovascular disorders and of ischemia reperfusion injuries.

Abstract: A wire electrode for cutting by electrical discharge machining may include a core and a covering. The core may include a metal or a metal alloy. The covering may surround the core and may include one or more covering layers, of which at least one contains a mixture of phases including at least one of ? or ?? brass and including ? brass. In the at least one covering layer that contains the mixture, the phases are present next to one another in a fine-grained microstructure having a mean grain size of 5 ?m or less in section perpendicular to the longitudinal axis of the wire electrode.

Abstract: The invention relates to a wire electrode (1, 1?) for electric discharge cutting processes and a method for the production thereof. The wire electrode (1, 1?) has a core (2) containing a metal or a metal alloy, and a coating (3, 4; 3, 4, 5) that surrounds the core (2) and includes one or more coating layers (3, 4, 5), at least one (3) of which contains a phase mixture of ?-brass and/or ??-brass and ?-brass. In said at least one coating layer (3) containing ?-brass and/or ??-brass and ?-brass, the ?-phase and/or ??-phase and the ?-phase are arranged next to each other in a fine-grained structure in which the mean size of the ?-brass and/or ??-brass grains and the ?-brass grains amounts to a maximum of 5 ?m relative to the cross-section extending perpendicular to the longitudinal axis of the wire electrode (1, 1?).

Abstract: The invention relates to a method for producing an optical arrangement (10, 300), in which an optical component (355, 20) is optically connected to at least one waveguide (90, 320, 330) provided on or in a carrier substrate (100, 310). In order to enable an optical component to be connected to an optical waveguide of a carrier substrate in a particularly simple and thus cost-effective manner, the invention provides for there to be arranged between the optical component (20, 355) and the waveguide (90, 320, 330) an adjustment device (40, 350) with at least one auxiliary waveguide (60, 410, 440), the waveguide ends (50, 70, 400, 420, 430, 450) of which are in each case movable and an optical adjustment between the optical component (20, 355) and the waveguide (90, 320, 330) of the carrier substrate (100, 310) is effected by a mechanical adjustment of the movable waveguide ends (50, 70, 400, 420, 430, 450).

Abstract: The invention relates to a planar optical circuit having a waveguide structure and at least one monolithic or hybrid integrated optical component. A mechanism for influencing the propagation of scattered light in the planar optical circuit in a targeted manner is employed and integrated into the planar optical circuit. The disadvantageous effects of scattered light are reduced in that scattered light is captured, absorbed, reflected or concentrated onto a narrow region by means of the integrated structures.

Abstract: The invention relates to a method for producing an optical arrangement (10, 300), in which an optical component (355, 20) is optically connected to at least one waveguide (90, 320, 330) provided on or in a carrier substrate (100, 310). In order to enable an optical component to be connected to an optical waveguide of a carrier substrate in a particularly simple and thus cost-effective manner, the invention provides for there to be arranged between the optical component (20, 355) and the waveguide (90, 320, 330) an adjustment device (40, 350) with at least one auxiliary waveguide (60, 410, 440), the waveguide ends (50, 70, 400, 420, 430, 450) of which are in each case movable and an optical adjustment between the optical component (20, 355) and the waveguide (90, 320, 330) of the carrier substrate (100, 310) is effected by a mechanical adjustment of the movable waveguide ends (50, 70, 400, 420, 430, 450).

Abstract: The invention relates to a thermo-optical waveguide switch which is located on a substrate. Said switch comprises a glass layer, through which a waveguide extends. A hollow chamber which lies beneath the waveguide thermally decouples the latter from the substrate. At least two supports are located in the hollow chamber to provide mechanical stability. One production method for obtaining a thermo-optical waveguide switch consists of creating a glass layer with an arrangement of perforations on a substrate. At least one hollow chamber containing at least two supports is formed by isotropically underetching the glass layer. The hollow chamber is subsequently sealed and a waveguide is formed above said hollow chamber. Another production method first creates a waveguide in a glass layer which is formed on a substrate.

Abstract: A configuration for multiplexing and/or demultiplexing the signals of at least two optical wavelength channels, is described. Provided in this case is a grating device having an optical grating, a first optical free beam region and a second optical free beam region. Accordingly, radiation is coupled into and out of the first free beam region via a coupling device which effects a flattening and/or widening of the field distribution of the light coupled in or out, at least in the plane of the first free beam region. This permits a transmission characteristic of the configuration to be flattened.

Abstract: The invention relates to a planar optical circuit having a waveguide structure and at least one monolithic or hybrid integrated optical component. A mechanism for influencing the propagation of scattered light in the planar optical circuit in a targeted manner is employed and integrated into the planar optical circuit. The disadvantageous effects of scattered light are reduced in that scattered light is captured, absorbed, reflected or concentrated onto a narrow region by means of the integrated structures.

Abstract: An optical configuration includes a Mach-Zehnder interferometer and a directional coupler. Both the Mach-Zehnder interferometer and the directional coupler have a first arm and a second arm. The Mach-Zehnder interferometer and the directional coupler share a common arm. A transceiving module for bidirectional optical data transmission, in particular for WDM systems with at least three wavelengths, includes two separate detection devices, an input/output optical waveguide, and an optical configuration as described above. The input/output optical waveguide receives and emits signals. The Mach-Zehnder interferometer separates signals of two wavelengths and feeds them to the separate detection devices.

Abstract: The invention relates to a module for multiplexing and/or demultiplexing optical signals, having at least one wavelength-selective filter for multiplexing or demultiplexing into the module optical signals which have been coupled in or out, light beams of at least one optical channel respectively striking a wavelength-selective filter at a specific angle of incidence and, in the process, being separated from the light beams of other optical channels or being combined therewith. According to the invention, at least one wavelength-selective filter (Fi) can be set with reference to the angle of incidence of the light beams. The invention makes available a module in the case of which the center wavelength of a filter can be set precisely on the basis of the adjustability of the angle of incidence and, moreover, a specific filter (Fi) can also be used for several wavelengths.

Abstract: An optical configuration includes a Mach-Zehnder interferometer and a directional coupler. Both the Mach-Zehnder interferometer and the directional coupler have a first arm and a second arm. The Mach-Zehnder interferometer and the directional coupler share a common arm.

Abstract: A configuration for multiplexing and/or demultiplexing the signals of at least two optical wavelength channels, is described. Provided in this case is a grating device having an optical grating, a first optical free beam region and a second optical free beam region. Accordingly, radiation is coupled into and out of the first free beam region via a coupling device which effects a flattening and/or widening of the field distribution of the light coupled in or out, at least in the plane of the first free beam region. This permits a transmission characteristic of the configuration to be flattened.

Abstract: A method and a wire electrode for the spark-erosive cutting of hard metal, whereby the wire electrode has a core and at least one outer coat surrounding the core and wearing during cutting. To avoid corrosion, as, for example, pitting, a wire electrode is chosen, the wearing outer coat of which consists of a metal or a metal alloy which is not nobler than the binder contained in the hard metal, and the metal or the metal alloy has an electrode potential which is less than or equal to &phgr;0=−0.28 V, referred to a standard hydrogen electrode.

Abstract: A method and a wire electrode for the spark-erosive cutting of hard metal, whereby the wire electrode has a core and at least one outer coat surrounding the core and wearing during cutting. To avoid corrosion, as, for example, pitting, a wire electrode is chosen, the wearing outer coat of which consists of a metal or a metal alloy which is not nobler than the binder contained in the hard metal, and the metal or the metal alloy has an electrode potential which is less than or equal to &PHgr;0=−0.28 V, referred to a standard hydrogen electrode.