Abstract: The present invention relates to a nucleic acid molecule encoding a chain myeloid capable of specifically binding to CD33, CD16 and CD123, wherein said nucleic molecule comprises: (a) a nucleic add molecule encoding a protein represented by SEQ ID NO:1; (b) a nucleic acid molecule represented by SEQ ID NO:2; (c) the nucleic add molecule of (b), wherein each thymine is replaced by urea; (d) a nucleic acid molecule encoding a protein having at least 98% sequence identity to the protein of (a); or (e) a nucleic add molecule that is degenerate with respect to the nucleic acid molecule of (b) or (c). The present invention further relates to a vector comprising the nucleic acid molecule of the invention, a host cell transformed or transfected with the nucleic acid molecule or the vector of the invention, as well as to a method for the production of a single chain myeloid capable of specifically binding to CD33, CD16 and CD123.

Abstract: The present invention relates to a nucleic acid molecule encoding a chain myeloid capable of specifically binding to CD33, CD16 and CD123, wherein said nucleic molecule comprises: (a) a nucleic add molecule encoding a protein represented by SEQ ID NO:1; (b) a nucleic acid molecule represented by SEQ ID NO:2; (c) the nucleic add molecule of (b), wherein each thymine is replaced by urea; (d) a nucleic acid molecule encoding a protein having at least 98% sequence identity to the protein of (a); or (e) a nucleic add molecule that is degenerate with respect to the nucleic acid molecule of (b) or (c). The present invention further relates to a vector comprising the nucleic acid molecule of the invention, a host cell transformed or transfected with the nucleic acid molecule or the vector of the invention, as well as to a method for the production of a single chain myeloid capable of specifically binding to CD33, CD16 and CD123.

Abstract: Methods, apparatus and articles of manufacture for communicating trust models to relying parties are provided herein. A method includes receiving a first item of cryptographic information from a first entity, wherein said first item of cryptographic information is derived from a second item of cryptographic information provided by an authentication source; receiving a request for access to the first item of cryptographic information from a second entity, wherein the request comprises the second item of cryptographic information; and providing identification information associated with the first item of cryptographic information to the second entity in response to said request.

Abstract: A method includes (a) receiving, at a computing device, a first certificate signing request (1CSR) from a certificate authority (CA), the 1CSR including an embedded second certificate signing request (2CSR), the 2CSR having been received by the CA from an entity seeking a signed certificate from the CA that validates an identity claim made by the entity in the 2CSR, the CA having performed a preliminary verification of the 2CSR prior to embedding it in the 1CSR, (b) verifying that the 1CSR came from the CA, (c) performing a verification procedure on the embedded 2CSR independent of the preliminary verification performed by the CA, to validate the identity claim made by the entity in the 2CSR, and (d) upon successfully validating the identity claim made by the entity in the 2CSR, sending a certificate to the CA, the certificate validating the identity claim made by the entity in the 2CSR.

Abstract: Method for digitally franking postal articles during which a digital postage paid impression is generated by a computer and applied to a postal article. Postal article-specific data for one or more postal articles to be created are generated in a first computer at a customer, and the access to a remote second computer at a service provider is granted. Postal article-specific data for one or more postal articles are transmitted to the second computer. The postal article-specific data are processed in the second computer, and data for a digital postage paid impression are generated for each postal article. Afterwards, processing data are transmitted to accounting component, and a deduction of the franking is carried out at the customer. The postal-article specific data are transmitted with a digital postage paid impression for each postal article to be created to the first computer, and the data are recorded in the first computer.

Abstract: A method for producing steel slabs, whereby the strand leaves an ingot mold with melt enclosed by a strand shell and, in a strand guide located downstream, the opening width of guide rolls mounted in segments with upper and lower frames can be set in a continuous manner with successive steps by adjusting elements that join said guide rolls. An oscillation around a center line of the opening width serves to modify the opening width in order to render the dynamic influences on the guide rolls negligibly small. The amplitude of the opening width oscillation is set to ta quantity, which des not provoke any plastic deformation of the strand shell. The actual opening width of the guide rolls is detected and the actuating force of the adjusting elements as well as the amplitude of the actuating force are determined at the same time.

Abstract: A a process for producing slabs from steel, in which the strand leaves a permanent mold with liquid melt enclosed by the strand shell and, in a downstream strand guiding assembly, the gap between guide rollers mounted in stands is set infinitely variably by adjusting elements connecting lower and upper frames, characterized by the following steps: a) the gap(s) is changed by an oscillation about a predeteminable center line (c) of the gap in such a way that the dynamic influences on the guide rollers are negligible, and no plastic deformation of the strand shell occurs; b) the current gap (s) is recorded, c) at the same time, the actuating force (F) of the adjusting elements and the amplitude (A) of the actuating force are determined, and d) with increasing amplitude (A) of the actuating force (F), the gap (s) is set to a predeterminable value and/or is pressure-controlled by at least one adjusting element.

Abstract: The invention relates to a method for producing steel slabs, whereby the strand leaves an ingot mold with melt enclosed by a strand shell and, in a strand guide located downstream, the opening width of guide rolls mounted in segments with upper and lower frames can be set in a continuous manner with successive steps by adjusting elements that join said guide rolls. An oscillation around a center line of the opening width serves to modify the opening width in order to render the dynamic influences on the guide rolls negligibly small. The amplitude of the opening width oscillation is set to a quantity, which does not provoke any plastic deformation of the strand shell. The actual opening width of the guide rolls is detected and the actuating force of the adjusting elements as well as the amplitude of the actuating force are determined at the same time.

Abstract: The invention relates to a process for producing slabs from steel, in which the strand leaves a permanent mold with liquid melt enclosed by the strand shell and, in a downstream strand guiding assembly, the gap between guide rollers mounted in stands is set infinitely variably by adjusting elements connecting lower and upper frames, characterized by the following steps:

Abstract: A strand guide, in particular for a continuous slab-casting plant for steel, with supporting segments in which frames are arranged that have rows of guide rollers and driving rollers arranged opposite one another, wherein the frames are held opposite one another by tie rods. Two guide members are provided at one end of a frame at equal distance from the center axis. The guide members are fastened to at least one fixed point via holding elements and are arranged conically at an opening angle relative to one another.