Abstract: dsRNAi oligonucleotides can be used in methods for the treatment of NASH, preferably the advanced fibrotic and/or cirrhotic stages thereof, using dosage regimens comprising a loading phase followed by a maintenance phase.

Abstract: A power split gearbox (1) has: a driveshaft (10), a plurality of identically shaped first planet shafts (20) rotatably arranged mounted around the driveshaft, wherein a first planet toothing and a second planet toothing are provided on the first planet shafts, wherein the first planet toothings are in mesh with the teeth of the drive toothing, a plurality of identically shaped second planet shafts (30) which are each arranged so as to be rotatably mounted on the radially outer side around the first planet shafts, wherein the second planet shafts have in each instance a third planet toothing and, a fourth planet toothing, and wherein two of the third planet toothings are in mesh with the teeth of one of the second planet toothings, and a central wheel (40) in mesh with the teeth of the fourth planet toothings.

Abstract: A power split gearbox (1) has a driveshaft (10) which is rotatably mounted so as to provide a drive and which has a drive toothing provided thereon in a torque-transmitting manner, a plurality of identically shaped first planet shafts (20) which are each arranged so as to be rotatably mounted around the driveshaft, wherein a first planet toothing and a second planet toothing which is axially offset relative to the latter are provided in each instance on the first planet shafts in a torque-transmitting manner, wherein the first planet toothings are in mesh with the teeth of the drive toothing, a plurality of identically shaped second planet shafts (30) which are each arranged so as to be rotatably mounted on the radially outer side around the first planet shafts, wherein the second planet shafts have in each instance a third planet toothing and, at an axial offset relative to the latter, a fourth planet toothing which are provided in a torque-transmitting manner thereon, and wherein two of the third planet too

Abstract: A torque transmission device for a ship for optionally transmitting a drive torque from a main drive or from an auxiliary drive to a propeller shaft of the ship, with a gear unit which can be driven by the main drive and which can be connected to the propeller shaft by a first clutch, and with a second clutch by which the auxiliary drive can be connected to the propeller shaft. The gear unit is received in a gear unit housing, the first clutch and/or second clutch are/is received in a clutch housing that is separate from the gear unit housing, and the first clutch, the second clutch and/or the auxiliary drive are arranged on the side of the gear unit remote of a propeller.

Abstract: The invention is directed to a torque transmission device for a ship for optionally transmitting a drive torque from a main drive or from an auxiliary drive to a propeller shaft (1, 2, 3) of the ship, with a gear unit (10, 11) which can be driven by the main drive and which can be connected to the propeller shaft by a first clutch (14), and with a second clutch (15) by which the auxiliary drive can be connected to the propeller shaft. The gear unit is received in a gear unit housing (6), the first clutch and/or second clutch are/is received in a clutch housing (7) that is separate from the gear unit housing, and the first clutch, the second clutch and/or the auxiliary drive are arranged on the side of the gear unit remote of a propeller.