Patents by Inventor Irena Tsyrlova

Irena Tsyrlova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stem cell mobilization and tissue repair and regeneration
    Patent number: 9428552
    Abstract: Stem cells are mobilized from bone marrow by administering an amount of Phe-Pro-His-Phe-Asp-Leu-Ser-His-Gly-Ser-Ala-Gln-Val-Ser-Asp-Lys-Pro (SEQ ID NO: 2) or Phe-Ala-His-Phe-Asp-Leu-Ser-His-Gly-Ser-Ala-Gln-Val-Ser-Asp-Lys-Pro (SEQ ID NO: 3) effective to mobilize the stem cells. This is useful for promoting bodily tissue regeneration in a patient in need of tissue regeneration treatment. Alternatively, the mobilized stem cells can be collected for transplant.
    Type: Grant
    Filed: November 18, 2013
    Date of Patent: August 30, 2016
    Assignee: Wellstat Therapeutics Corporation
    Inventors: Irena Tsyrlova, Fawn Petty, Reid W. von Borstel, Julian Reading, Jiong Pei, Joel Saydoff
  • Stem Cell Mobilization and Tissue Repair and Regeneration
    Publication number: 20160016997
    Abstract: Stem cells are mobilized from bone marrow by administering an amount of Phe-Pro-His-Phe-Asp-Leu-Ser-His-Gly-Ser-Ala-Gln-Val-Ser-Asp-Lys-Pro (SEQ ID NO: 2) or Phe-Ala-His-Phe-Asp-Leu-Ser-His-Gly-Ser-Ala-Gln-Val-Ser-Asp-Lys-Pro (SEQ ID NO: 3) effective to mobilize the stem cells. This is useful for promoting bodily tissue regeneration in a patient in need of tissue regeneration treatment. Alternatively, the mobilized stem cells can be collected for transplant.
    Type: Application
    Filed: November 18, 2013
    Publication date: January 21, 2016
    Inventors: Irena Tsyrlova, Fawn Petty, Reid W. von Borstel, Julian Reading, Jiong Pei, Joel Saydoff
  • Stem Cell Mobilization and Tissue Repair and Regeneration
    Publication number: 20140088006
    Abstract: Stem cells are mobilized from bone marrow by administering an amount of Phe-Pro-His-Phe-Asp-Leu-Ser-His-Gly-Ser-Ala-Gin-Val (SEQ ID NO: 1) effective to mobilize the stem cells. This method is useful for promoting preservation, repair, or regeneration of bodily tissue, or revascularization, in a patient in need of such treatment. Alternatively, the mobilized stem cells can be collected for transplant.
    Type: Application
    Filed: May 18, 2012
    Publication date: March 27, 2014
    Applicant: Wellstat Therapeutics Corporation
    Inventors: Irena Tsyrlova, Fawn Petty, Reid W. Von Borstel, Julian Reading
  • HEMOGLOBIN ALPHA CHAIN PEPTIDE FRAGMENTS USEFUL FOR INHIBITING STEM CELL PROLIFERATION
    Publication number: 20100041147
    Abstract: Disclosed and claimed are methods for the isolation and use of stem cell inhibiting factors for regulating the abnormal stem cell cycle and for accelerating the post-chemotherapy peripheral blood cell recovery. Also disclosed and claimed are the inhibitors of stem cell proliferation.
    Type: Application
    Filed: August 3, 2009
    Publication date: February 18, 2010
    Applicant: WELLSTAT THERAPEUTICS CORPORATION
    Inventors: Irena Tsyrlova, Stephen D. Wolpe
  • Stimulator of stem cell division
    Patent number: 7115267
    Abstract: Disclosed and claimed are methods for the isolation and use of stem cell modulating factors for regulating stem cell cycle and for accelerating the post-chemotherapy peripheral blood cell recovery. Also disclosed and claimed are the inhibitors and stimulators of stem cell proliferation.
    Type: Grant
    Filed: February 12, 2004
    Date of Patent: October 3, 2006
    Assignee: Wellstat Therapeutics Corporation
    Inventors: Stephen D. Wolpe, Irena Tsyrlova
  • Inhibitor and stimulator of stem cell proliferation and uses thereof
    Publication number: 20060166863
    Abstract: Disclosed and claimed are methods for the isolation and use of stem cell modulating factors for regulating stem cell cycle and for accelerating the post-chemotherapy peripheral blood cell recovery. Also disclosed and claimed are the inhibitors and stimulators of stem cell proliferation.
    Type: Application
    Filed: March 23, 2006
    Publication date: July 27, 2006
    Applicant: WELLSTAT THERAPEUTICS CORPORATION
    Inventors: Stephen Wolpe, Irena Tsyrlova
  • Inhibitor of stem cell proliferation and uses thereof
    Publication number: 20050043218
    Abstract: Disclosed and claimed are methods for the isolation and use of stem cell inhibiting factors for regulating the abnormal stem cell cycle and for accelerating the post-chemotherapy peripheral blood cell recovery. Also disclosed and claimed are the inhibitors of stem cell proliferation.
    Type: Application
    Filed: July 23, 2004
    Publication date: February 24, 2005
    Applicant: WELLSTAT THERAPEUTICS CORPORATION
    Inventors: Irena Tsyrlova, Stephen Wolpe
  • Hemoglobin alpha chain peptide fragments useful for inhibiting stem cell proliferation
    Patent number: 6858583
    Abstract: Disclosed and claimed are methods for the isolation and use of stem cell inhibiting factors for regulating the abnormal stem cell cycle and for accelerating the post-chemotherapy peripheral blood cell recovery. Also disclosed and claimed are the inhibitors of stem cell proliferation.
    Type: Grant
    Filed: June 18, 2003
    Date of Patent: February 22, 2005
    Assignee: Wellstat Therapeutics Corporation
    Inventors: Irena Tsyrlova, Stephen D. Wolpe
  • Inhibitor and stimulator of stem cell proliferation and uses thereof
    Patent number: 6784155
    Abstract: Disclosed and claimed are methods for the isolation and use of stem cell modulating factors for regulating stem cell cycle and for accelerating the post-chemotherapy peripheral blood cell recovery. Also disclosed and claimed are the inhibitors and stimulators of stem cell proliferation.
    Type: Grant
    Filed: April 3, 1997
    Date of Patent: August 31, 2004
    Assignee: Wellstat Therapeutics Corporation
    Inventors: Stephen D. Wolpe, Irena Tsyrlova
  • Inhibitor and stimulator of stem cell proliferation and uses thereof
    Publication number: 20040167060
    Abstract: Disclosed and claimed are methods for the isolation and use of stem cell modulating factors for regulating stem cell cycle and for accelerating the post-chemotherapy peripheral blood cell recovery. Also disclosed and claimed are the inhibitors and stimulators of stem cell proliferation.
    Type: Application
    Filed: February 12, 2004
    Publication date: August 26, 2004
    Applicant: Wellstat Therapeutics Corporation
    Inventors: Stephen D. Wolpe, Irena Tsyrlova
  • Hemoglobin alpha chain peptide fragments useful for inhibiting stem cell proliferation
    Publication number: 20040081640
    Abstract: Disclosed and claimed are methods for the isolation and use of stem cell inhibiting factors for regulating the abnormal stem cell cycle and for accelerating the post-chemotherapy peripheral blood cell recovery. Also disclosed and claimed are the inhibitors of stem cell proliferation.
    Type: Application
    Filed: June 18, 2003
    Publication date: April 29, 2004
    Applicant: WELLSTAT THERAPEUTICS CORPORATION
    Inventors: Irena Tsyrlova, Stephen D. Wolpe
  • Inhibitor of stem cell proliferation and uses thereof
    Patent number: 6610654
    Abstract: Disclosed and claimed are methods for the isolation and use of stem cell inhibiting factors for regulating the abnormal stem cell cycle and for accelerating the post-chemotherapy peripheral blood cell recovery. Also disclosed and claimed are the inhibitors of stem cell proliferation.
    Type: Grant
    Filed: April 24, 2002
    Date of Patent: August 26, 2003
    Assignee: Wellstat Therapeutics Corporation
    Inventors: Irena Tsyrlova, Stephen D. Wolfe
  • Inhibitor of stem cell proliferation and uses thereof
    Publication number: 20030104984
    Abstract: Disclosed and claimed are methods for the isolation and use of stem cell inhibiting factors for regulating the abnormal stem cell cycle and for accelerating the post-chemotherapy peripheral blood cell recovery. Also disclosed and claimed are the inhibitors of stem cell proliferation.
    Type: Application
    Filed: April 24, 2002
    Publication date: June 5, 2003
    Applicant: Pro-Neuron Inc.
    Inventors: Irena Tsyrlova, Stephen D. Wolpe
  • Inhibitor of stem cell proliferation and uses thereof
    Patent number: 6432917
    Abstract: Disclosed and claimed are methods for the isolation and use of stem cell inhibiting factors for regulating the abnormal stem cell cycle and for accelerating the post-chemotherapy peripheral blood cell recovery. Also disclosed and claimed are the inhibitors of stem cell proliferation.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 13, 2002
    Assignee: Pro-Neuron, Inc.
    Inventors: Vladimir Kozlov, Irena Tsyrlova
  • Inhibitor of stem cell proliferation and uses thereof
    Publication number: 20020098583
    Abstract: Disclosed and claimed are methods for the isolation and use of stem cell inhibiting factors for regulating the abnormal stem cell cycle and for accelerating the post-chemotherapy peripheral blood cell recovery. Also disclosed and claimed are the inhibitors of stem cell proliferation.
    Type: Application
    Filed: April 23, 2001
    Publication date: July 25, 2002
    Applicant: Pro-Neuron, Inc.
    Inventors: Vladimir Kozlov, Irena Tsyrlova
  • Hemoglobin alpha and beta chain peptide fragments useful for inhibiting stem cell proliferation
    Patent number: 6090782
    Abstract: Disclosed and claimed are methods for the isolation and use of stem cell inhibiting factors for regulating the abnormal stem cell cycle and for accelerating the post-chemotherapy peripheral blood cell recovery. Also disclosed and claimed are the inhibitors of stem cell proliferation.
    Type: Grant
    Filed: January 12, 1998
    Date of Patent: July 18, 2000
    Assignee: Pro-Neuron, Inc.
    Inventors: Irena Tsyrlova, Stephen D. Wolpe
  • Inhibitor of stem cell proliferation and uses thereof
    Patent number: 6022848
    Abstract: Disclosed and claimed are methods for the isolation and use of stem cell inhibiting factors for regulating the abnormal stem cell cycle and for accelerating the post-chemotherapy peripheral blood cell recovery. Also disclosed and claimed are the inhibitors of stem cell proliferation.
    Type: Grant
    Filed: September 30, 1994
    Date of Patent: February 8, 2000
    Assignee: Pro-Neuron, Inc.
    Inventors: Vladimir Kozlov, Irena Tsyrlova
  • Hemoglobin alpha chain peptide fragments useful for inhibiting stem cell proliferation
    Patent number: 5939391
    Abstract: Disclosed and claimed are methods for the isolation and use of stem cell inhibiting factors for regulating the abnormal stem cell cycle and for accelerating the post-chemotherapy peripheral blood cell recovery. Also disclosed and claimed are the inhibitors of stem cell proliferation.
    Type: Grant
    Filed: September 28, 1995
    Date of Patent: August 17, 1999
    Assignee: Pro-Neuron, Inc.
    Inventors: Irena Tsyrlova, Stephen D. Wolpe