Patents by Inventor Irene Griswold-Prenner

Irene Griswold-Prenner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC ANTIBODIES FOR TREATMENT OF NEURODEGENERATION
    Publication number: 20200385450
    Abstract: The invention provides therapeutic antibodies and methods for treatment of diseases associated with diseases associated with aggregation of ?-synuclein, e.g., in the brain of a subject. Such methods provide administration of therapeutic antibodies to elicit a beneficial immunogenic response against aggregation of ?-synuclein. The methods are particularly useful for prophylactic and therapeutic treatment of diseases associated with the formation of Lewy bodies, e.g., Parkinson's disease.
    Type: Application
    Filed: August 20, 2020
    Publication date: December 10, 2020
    Inventors: Irene Griswold-Prenner, Karen Chen
  • Therapeutic antibodies for treatment of neurodegeneration
    Patent number: 10766954
    Abstract: The invention provides therapeutic antibodies and methods for treatment of diseases associated with diseases associated with aggregation of ?-synuclein, e.g., in the brain of a subject. Such methods provide administration of therapeutic antibodies to elicit a beneficial immunogenic response against aggregation of ?-synuclein. The methods are particularly useful for prophylactic and therapeutic treatment of diseases associated with the formation of Lewy bodies, e.g., Parkinson's disease.
    Type: Grant
    Filed: April 5, 2017
    Date of Patent: September 8, 2020
    Assignee: Imago Pharmaceuticals, Inc.
    Inventors: Irene Griswold-Prenner, Karen Chen
  • Methods of Treating a Tauopathy
    Publication number: 20200102375
    Abstract: The present disclosure provides methods for treating a tauopathy (e.g., an acute tauopathy) in an individual by administering an anti-Tau antibody to the individual. Also provided are methods of treating traumatic brain injury and methods of treating stroke in an individual by administering an anti-Tau antibody to the individual.
    Type: Application
    Filed: April 29, 2019
    Publication date: April 2, 2020
    Inventors: Irene Griswold-Prenner, Graham Parry
  • THERAPEUTIC ANTIBODIES FOR TREATMENT OF NEURODEGENERATION
    Publication number: 20190330315
    Abstract: The invention provides therapeutic antibodies and methods for treatment of diseases associated with diseases associated with aggregation of ?-synuclein, e.g., in the brain of a subject. Such methods provide administration of therapeutic antibodies to elicit a beneficial immunogenic response against aggregation of ?-synuclein. The methods are particularly useful for prophylactic and therapeutic treatment of diseases associated with the formation of Lewy bodies, e.g., Parkinson's disease.
    Type: Application
    Filed: April 5, 2017
    Publication date: October 31, 2019
    Inventors: Irene Griswold-Prenner, Karen Chen
  • Tau peptides, anti-tau antibodies, and methods of use thereof
    Patent number: 10400018
    Abstract: Isolated tau peptides, and compositions comprising the peptides are disclosed. Further provided are antibodies specific for an isolated tau peptide. Methods of using the isolated tau peptide in diagnostic and treatment including using a pharmaceutical composition comprising the isolated tau peptide for stimulating an immune response in an individual to a tau peptide, and methods of using antibodies in detection, diagnosis, and treatment of disorders including a tauopathy are further provided.
    Type: Grant
    Filed: February 14, 2014
    Date of Patent: September 3, 2019
    Assignee: iPierian, Inc.
    Inventors: Irene Griswold-Prenner, Graham Parry, Tony SangYoung Byun
  • TREATMENT OF FIBROTIC DISORDERS WITH JUN N-TERMINAL KINASE INHIBITORS
    Publication number: 20190231751
    Abstract: The present disclosure provides a method of treating diseases, conditions or disorders associated with fibrosis in a mammal using inhibitors of the Jun N-terminal kinase (JNK) pathway. The present disclosure in particular provides methods of treating diseases, conditions or disorders associated with fibrosis using a specific class of small molecule JNK inhibitors.
    Type: Application
    Filed: September 11, 2017
    Publication date: August 1, 2019
    Inventors: Irene Griswold-Prenner, Karen Chen
  • Methods of Treating a Tauopathy
    Publication number: 20190169275
    Abstract: The present disclosure provides methods of treating a tauopathy, involving administering an anti-Tau antibody. The present disclosure also provides anti-Tau antibodies, and formulations comprising same, for use in the methods.
    Type: Application
    Filed: July 16, 2018
    Publication date: June 6, 2019
    Applicant: iPierian, Inc.
    Inventors: Irene Griswold-Prenner, Nancy E. Stagliano, Vu Cao Dang
  • Methods of treating a tauopathy
    Patent number: 10040847
    Abstract: The present disclosure provides methods of treating a tauopathy, involving administering an anti-Tau antibody. The present disclosure also provides anti-Tau antibodies, and formulations comprising same, for use in the methods.
    Type: Grant
    Filed: January 3, 2017
    Date of Patent: August 7, 2018
    Assignee: iPierian, Inc.
    Inventors: Irene Griswold-Prenner, Nancy E. Stagliano, Vu Cao Dang
  • Methods of treating a tauopathy
    Patent number: 9777058
    Abstract: The present disclosure provides methods of treating a tauopathy, involving administering an anti-Tau antibody. The present disclosure also provides anti-Tau antibodies, and formulations comprising same, for use in the methods.
    Type: Grant
    Filed: August 11, 2016
    Date of Patent: October 3, 2017
    Assignee: iPierian, Inc.
    Inventors: Irene Griswold-Prenner, Nancy E. Stagliano, Vu Cao Dang
  • METHODS OF TREATING A TAUOPATHY
    Publication number: 20170174755
    Abstract: The present disclosure provides methods of treating a tauopathy, involving administering an anti-Tau antibody. The present disclosure also provides anti-Tau antibodies, and formulations comprising same, for use in the methods.
    Type: Application
    Filed: January 3, 2017
    Publication date: June 22, 2017
    Inventors: Irene GRISWOLD-PRENNER, Nancy E. STAGLIANO, Vu Cao DANG
  • Methods of treating a tauopathy
    Patent number: 9567395
    Abstract: The present disclosure provides methods of treating a tauopathy, involving administering an anti-Tau antibody. The present disclosure also provides anti-Tau antibodies, and formulations comprising same, for use in the methods.
    Type: Grant
    Filed: August 15, 2013
    Date of Patent: February 14, 2017
    Assignee: IPIERIAN, INC.
    Inventors: Irene Griswold-Prenner, Nancy E. Stagliano, Vu Cao Dang
  • METHODS OF TREATING A TAUOPATHY
    Publication number: 20160355578
    Abstract: The present disclosure provides methods of treating a tauopathy, involving administering an anti-Tau antibody. The present disclosure also provides anti-Tau antibodies, and formulations comprising same, for use in the methods.
    Type: Application
    Filed: August 11, 2016
    Publication date: December 8, 2016
    Inventors: Irene GRISWOLD-PRENNER, Nancy E. Stagliano, Vu Cao Dang
  • TAU PEPTIDES, ANTI-TAU ANTIBODIES, AND METHODS OF USE THEREOF
    Publication number: 20160347804
    Abstract: Isolated tau peptides, and compositions comprising the peptides are disclosed. Further provided are antibodies specific for an isolated tau peptide. Methods of using the isolated tau peptide in diagnostic and treatment including using a pharmaceutical composition comprising the isolated tau peptide for stimulating an immune response in an individual to a tau peptide, and methods of using antibodies in detection, diagnosis, and treatment of disorders including a tauopathy are further provided.
    Type: Application
    Filed: February 14, 2014
    Publication date: December 1, 2016
    Inventors: Irene GRISWOLD-PRENNER, Graham PARRY, Tony SangYoung BYUN
  • METHODS OF TREATING A TAUOPATHY
    Publication number: 20160289309
    Abstract: The present disclosure provides methods for treating a tauopathy (e.g., an acute tauopathy) in an individual by administering an anti-Tau antibody to the individual. Also provided are methods of treating traumatic brain injury and methods of treating stroke in an individual by administering an anti-Tau antibody to the individual.
    Type: Application
    Filed: November 25, 2014
    Publication date: October 6, 2016
    Applicant: IPIERIAN, INC.
    Inventors: Irene GRISWOLD-PRENNER, Graham PARRY
  • Methods of treating a tauopathy
    Patent number: 9447180
    Abstract: The present disclosure provides methods of treating a tauopathy, involving administering an anti-Tau antibody. The present disclosure also provides anti-Tau antibodies, and formulations comprising same, for use in the methods.
    Type: Grant
    Filed: May 6, 2015
    Date of Patent: September 20, 2016
    Assignee: iPierian, Inc.
    Inventors: Irene Griswold-Prenner, Nancy E. Stagliano, Vu Cao Dang
  • Use of perlecan domain V in treating amyloidogenic disease
    Patent number: 9358273
    Abstract: The application reports that perlecan domain V (DV) or the LG3 domain thereof reduces deposition and toxicity of A? peptide, the major component of plaques in Alzheimer's disease. Methods of using DV, LG3 and related molecules in treatment of amyloidogenic diseases, particularly Alzheimer's disease, are provided.
    Type: Grant
    Filed: January 6, 2011
    Date of Patent: June 7, 2016
    Assignee: THE TEXAS A&M UNIVERSITY SYSTEM
    Inventors: Gregory J. Bix, Sarah Wright, Irene Griswold-Prenner
  • METHODS OF TREATING A TAUOPATHY
    Publication number: 20160122421
    Abstract: The present disclosure provides methods of treating a tauopathy, involving administering an anti-Tau antibody. The present disclosure also provides anti-Tau antibodies, and formulations comprising same, for use in the methods.
    Type: Application
    Filed: June 9, 2014
    Publication date: May 5, 2016
    Inventors: Irene GRISWOLD-PRENNER, Nancy E. STAGILANO, Vu Cao DANG, Sami HUSSAIN, Jessica Michelle BRIGHT
  • METHODS OF TREATING A TAUOPATHY
    Publication number: 20150239963
    Abstract: The present disclosure provides methods of treating a tauopathy, involving administering an anti-Tau antibody. The present disclosure also provides anti-Tau antibodies, and formulations comprising same, for use in the methods.
    Type: Application
    Filed: August 15, 2013
    Publication date: August 27, 2015
    Inventors: Irene Griswold-Prenner, Nancy E. Stagliano, Vu Cao Dang
  • METHODS OF TREATING A TAUOPATHY
    Publication number: 20150232544
    Abstract: The present disclosure provides methods of treating a tauopathy, involving administering an anti-Tau antibody. The present disclosure also provides anti-Tau antibodies, and formulations comprising same, for use in the methods.
    Type: Application
    Filed: May 6, 2015
    Publication date: August 20, 2015
    Inventors: Irene GRISWOLD-PRENNER, Nancy E. STAGLIANO, Vu Cao DANG
  • Methods of treating a tauopathy
    Patent number: 9051367
    Abstract: The present disclosure provides methods of treating a tauopathy, involving administering an anti-Tau antibody. The present disclosure also provides anti-Tau antibodies, and formulations comprising same, for use in the methods.
    Type: Grant
    Filed: September 9, 2014
    Date of Patent: June 9, 2015
    Assignee: iPierian, Inc.
    Inventors: Irene Griswold-Prenner, Nancy E. Stagliano, Vu Cao Dang