Patents by Inventor Iris Alchanati

Iris Alchanati has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for enhancing the therapeutic efficacy of topoisomerase inhibitors
    Patent number: 8067473
    Abstract: Disclosed are methods and compositions useful in identifying an E3 ubiquitin ligase inhibitor and modulating cell growth, comprising contacting a cell with an effective amount of an inhibitor of an E3 ubiquitin ligase, and contacting the cell with an effective amount of a topoisomerase inhibitor, wherein the treatment with the E3 ubiquitin ligase inhibitor and topoisomerase inhibitor modulates cell growth in comparison to a cell treated with the topoisomerase inhibitor alone. The present invention further provides methods for identifying and making an E3 ubiquitin ligase inhibitor.
    Type: Grant
    Filed: January 16, 2008
    Date of Patent: November 29, 2011
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventors: Omri Erez, Iris Alchanati, Philippe Nakache
  • Methods for enhancing the therapeutic efficacy of topoisomerase inhibitors
    Publication number: 20080227727
    Abstract: Disclosed are methods and compositions useful in identifying an E3 ubiquitin ligase inhibitor and modulating cell growth, comprising contacting a cell with an effective amount of an inhibitor of an E3 ubiquitin ligase, and contacting the cell with an effective amount of a topoisomerase inhibitor, wherein the treatment with the E3 ubiquitin ligase inhibitor and topoisomerase inhibitor modulates cell growth in comparison to a cell treated with the topoisomerase inhibitor alone. The present invention further provides methods for identifying and making an E3 ubiquitin ligase inhibitor.
    Type: Application
    Filed: January 16, 2008
    Publication date: September 18, 2008
    Inventors: Omri Erez, Iris Alchanati, Philippe Nakache