Patents by Inventor Irving Goldschneider

Irving Goldschneider has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acids encoding a chimeric polypeptide comprising IL-7 and HGF-beta chain and methods of use
    Patent number: 8163520
    Abstract: The present invention relates to a single-chain or chimeric polypeptide comprising a cytokine and a growth factor linked by at least one amino acid residue, and wherein the chimeric polypeptide enhances the proliferation and/or differentiation of hematopoietic precursor cells. In particular the invention relates to, a chimeric polypeptide comprising the beta-chain of hepatocyte growth factor, and IL-7 linked by at least one amino acid, and wherein the chimeric polypeptide demonstrates pre-pro-B proliferation and growth stimulating activity.
    Type: Grant
    Filed: August 7, 2009
    Date of Patent: April 24, 2012
    Assignee: University of Connecticut
    Inventors: Irving Goldschneider, Laijun Lai
  • Chimeric Cytokine of IL-7 and Beta Chain of HGF and Methods of Use
    Publication number: 20110200562
    Abstract: The present invention relates to a single-chain or chimeric polypeptide comprising a cytokine and a growth factor linked by at least one amino acid residue, and wherein the chimeric polypeptide enhances the proliferation and/or differentiation of hematopoietic precursor cells. In particular the invention relates to, a chimeric polypeptide comprising the beta-chain of hepatocyte growth factor, and IL-7 linked by at least one amino acid, and wherein the chimeric polypeptide demonstrates pre-pro-B proliferation and growth stimulating activity.
    Type: Application
    Filed: August 7, 2009
    Publication date: August 18, 2011
    Inventors: Irving Goldschneider, Laijun Lai
  • Chimeric cytokine of IL-7 and beta-chain of HGF and methods of use
    Patent number: 7578998
    Abstract: The present invention relates to a single-chain or chimeric polypeptide comprising a cytokine and a growth factor linked by at least one amino acid residue, and wherein the chimeric polypeptide enhances the proliferation and/or differentiation of hematopoietic precursor cells. In particular the invention relates to, a chimeric polypeptide comprising the beta-chain of hepatocyte growth factor, and IL-7 linked by at least one amino acid, and wherein the chimeric polypeptide demonstrates pre-pro-B proliferation and growth stimulating activity.
    Type: Grant
    Filed: November 17, 2006
    Date of Patent: August 25, 2009
    Assignee: University of Connecticut
    Inventors: Irving Goldschneider, Laijun Lai
  • Chimeric cytokine of IL-7 and beta-chain of HGF and methods of use
    Publication number: 20070122380
    Abstract: The present invention relates to a single-chain or chimeric polypeptide comprising a cytokine and a growth factor linked by at least one amino acid residue, and wherein the chimeric polypeptide enhances the proliferation and/or differentiation of hematopoietic precursor cells. In particular the invention relates to, a chimeric polypeptide comprising the beta-chain of hepatocyte growth factor, and IL-7 linked by at least one amino acid, and wherein the chimeric polypeptide demonstrates pre-pro-B proliferation and growth stimulating activity.
    Type: Application
    Filed: November 17, 2006
    Publication date: May 31, 2007
    Inventors: Irving Goldschneider, Laijun Lai
  • Hybrid cytokine of IL-7 and beta-chain of hepatocyte growth factor
    Publication number: 20040167317
    Abstract: A hybrid cytokine comprising the B-chain of hepatocyte growth factor and IL-7, linked by a linker molecule, having pre-pro-B growth stimulating activity.
    Type: Application
    Filed: March 3, 2004
    Publication date: August 26, 2004
    Inventors: Irving Goldschneider, Laijun Lai
  • Hybrid cytokine of IL-7 and &bgr;-chain of hepatocyte growth factor
    Patent number: 6749847
    Abstract: A hybrid cytokine comprising the B-chain of hepatocyte growth factor and IL-7, linked by a linker molecule, having pre-pro-B growth stimulating activity.
    Type: Grant
    Filed: March 30, 2001
    Date of Patent: June 15, 2004
    Assignee: The University of Connecticut
    Inventors: Irving Goldschneider, Laijun Lai
  • Hybrid cytokine of IL-7 and beta-chain of hepatocyte growth factor
    Publication number: 20020058791
    Abstract: A hybrid cytokine comprising the B-chain of hepatocyte growth factor and IL-7, linked by a linker molecule, having pre-pro-B growth stimulating activity.
    Type: Application
    Filed: March 30, 2001
    Publication date: May 16, 2002
    Inventors: Irving Goldschneider, Laijun Lai