Patents by Inventor Isabelle Maillet
Isabelle Maillet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11945843Abstract: Disclosed are double stranded RNA molecules that are toxic to coleopteran insects. In particular, interfering RNA molecules capable of interfering with pest target genes and that are toxic to the target pest are provided. Further, methods of making and using the interfering RNA, for example in transgenic plants or as the active ingredient in a composition, to confer protection from insect damage are disclosed.Type: GrantFiled: August 1, 2017Date of Patent: April 2, 2024Assignee: SYNGENTA PARTICIPATIONS AGInventors: Kevin L. Donohue, Yann Naudet, Pascale Feldmann, Lies Degrave, Isabelle Maillet
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Patent number: 11286476Abstract: Methods of substantially retaining or otherwise preserving the biological activity of a dsRNA, present in a cell, to post-transcriptionally silence the expression of a gene in a target organism, comprising the step of adding to the cell composition a compound having the function of a protein—or amine—cross linking agent and/or an acid, and compositions comprising the cells comprising dsRNA, and protein cross linking agents and/or acids, as well as the use of the cross linking agents and/or acids in the method.Type: GrantFiled: September 28, 2017Date of Patent: March 29, 2022Assignees: SYNGENTA PARTICIPATIONS AG, Devgen NVInventors: Pascale Feldmann, Jeffrey David Fowler, Nema Devi Jhurry, Isabelle Maillet, Marta Omedes Pujol
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Publication number: 20220049256Abstract: Disclosed are double stranded RNA (dsRNA) molecules that are toxic to insect pests. In particular, interfering RNA molecules capable of modulating expression of a pest insect target gene and that are toxic to the insect pest are provided. Further, methods of making and using the interfering RNA, for example as the active ingredient in an insecticidal composition or in a transgenic plant, to confer protection from insect damage are disclosed.Type: ApplicationFiled: November 5, 2021Publication date: February 17, 2022Applicant: DEVGEN NVInventors: Yann NAUDET, Myriam BEGHYN, Lien DE SCHRIJVER, Isabelle MAILLET, Annelies PHILIPS
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Patent number: 11198868Abstract: Disclosed are double stranded RNA (dsRNA) molecules that are toxic to insect pests. In particular, interfering RNA molecules capable of modulating expression of a pest insect target gene and that are toxic to the insect pest are provided. Further, methods of making and using the interfering RNA, for example as the active ingredient in an insecticidal composition or in a transgenic plant, to confer protection from insect damage are disclosed.Type: GrantFiled: November 6, 2018Date of Patent: December 14, 2021Assignee: DEVGEN NVInventors: Yann Naudet, Myriam Beghyn, Lien De Schrijver, Isabelle Maillet, Annelies Philips
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Publication number: 20210186029Abstract: Disclosed are double stranded RNA (dsRNA) molecules that are toxic to insect pests. In particular, interfering RNA molecules capable of modulating expression of a pest insect target gene and that are toxic to the insect pest are provided. Further, methods of making and using the interfering RNA, for example as the active ingredient in an insecticidal composition or in a transgenic plant, to confer protection from insect damage are disclosed.Type: ApplicationFiled: November 6, 2018Publication date: June 24, 2021Applicant: SYNGENTA PARTICIPATIONS AGInventors: Yann Naudet, Myriam Beghyn, Lien De Schrijver, Annelies Philips, Isabelle Maillet
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Patent number: 10898507Abstract: Disclosed are double stranded RNA molecules that are toxic to coleopteran insects. In particular, interfering RNA molecules capable of interfering with pest target genes and that are toxic to the target pest are provided. Further, methods of making and using the interfering RNA, for example in transgenic plants or as the active ingredient in a composition, to confer protection from insect damage are disclosed.Type: GrantFiled: August 1, 2017Date of Patent: January 26, 2021Assignee: SYNGENTA PARTICIPATIONS AGInventors: Kevin V. Donohue, Yann Naudet, Pascale Feldmann, Lies Degrave, Isabelle Maillet
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Publication number: 20200239891Abstract: Disclosed are double stranded RNA (dsRNA) molecules that are toxic to insect pests. In particular, interfering RNA molecules capable of modulating expression of a pest insect target gene and that are toxic to the insect pest are provided. Further, methods of making and using the interfering RNA, for example as the active ingredient in an insecticidal composition or in a transgenic plant, to confer protection from insect damage are disclosed.Type: ApplicationFiled: November 6, 2018Publication date: July 30, 2020Applicant: DEVGEN NVInventors: Yann Naudet, Myriam Beghyn, Lien De Schrijver, Isabelle Maillet, Annelies Philips
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Publication number: 20200181611Abstract: The present invention provides an RNA comprising in the 5? to 3? direction a first sequence and a second sequence, the first sequence being spaced apart from the second sequence by a spacer sequence, the first and second sequences being substantially complementary and forming a duplex via Watson and Crick base pairing, the second sequence being able to hybridise with the mRNA of a target gene in an organism, the RNA being substantially in the form of a hairpin, the second sequence being fully complementary to the said mRNA along the region at which it hybridises, the first sequence comprising nucleotide bases which do not Watson and Crick base pair with the corresponding bases in the second sequence of the duplex wherein the duplex does not comprise regions of 3 or more consecutive mismatched bases or an RNA comprising in the 5? to 3? direction a first sequence and a second sequence, the first sequence being spaced apart from the second sequence by a spacer sequence, the first and second sequences being substType: ApplicationFiled: October 19, 2016Publication date: June 11, 2020Applicant: Devgen NVInventors: Wendy MADDELEIN, Isabelle MAILLET
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Publication number: 20200045977Abstract: The present invention provides a method of substantially retaining or otherwise preserving the biological activity of a dsRNA, present in a cell, to post-transcriptionally silence the expression of a gene in a target organism, comprising the step of adding to the cell composition a compound having the function of a protein—or amine—cross linking agent and/or an acid. The invention also comprises compositions comprising the cells comprising dsRNA, and protein cross linking agents and/or acids, as well as the use of said cross linking agents and/or acids in the method.Type: ApplicationFiled: September 28, 2017Publication date: February 13, 2020Applicants: SYNGENTA PARTICIPATIONS AG, Devgen NVInventors: Pascale FELDMANN, Jeffrey David FOWLER, Nema Devi JHURRY, Isabelle MAILLET, Marta OMEDES PUJOL
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Publication number: 20190185526Abstract: Disclosed are double stranded RNA molecules that are toxic to coleopteran insects. In particular, interfering RNA molecules capable of interfering with pest target genes and that are toxic to the target pest are provided. Further, methods of making and using the interfering RNA, for example in transgenic plants or as the active ingredient in a composition, to confer protection from insect damage are disclosed.Type: ApplicationFiled: August 1, 2017Publication date: June 20, 2019Applicant: Syngenta Participations AGInventors: Kevin L. DONOHUE, Yann NAUDET, Pascale FELDMANN, Lies DEGRAVE, Isabelle MAILLET
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Publication number: 20190177736Abstract: Disclosed are double stranded RNA molecules that are toxic to coleopteran insects. In particular, interfering RNA molecules capable of interfering with pest target genes and that are toxic to the target pest are provided. Further, methods of making and using the interfering RNA, for example in transgenic plants or as the active ingredient in a composition, to confer protection from insect damage are disclosed.Type: ApplicationFiled: August 1, 2017Publication date: June 13, 2019Applicant: Syngenta Pariticpations AGInventors: Kevin L. DONOHUE, Yann NAUDET, Lies DEGRAVE, Isabelle MAILLET, Pascale FELDMANN
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Publication number: 20180289015Abstract: The present invention provides a method of substantially retaining or otherwise preserving the biological activity of a dsRNA, present in a cell lysate, to post-transcriptionally silence the expression of a gene in a target organism, comprising the step of adding to the lysate a compound having the function of a protein- or amine-cross linking agent. The invention also comprises compositions comprising the lysate comprising dsRNA, and protein cross linking agents, as well as the use of said agents in the method.Type: ApplicationFiled: September 27, 2016Publication date: October 11, 2018Applicants: SYNGENTA CROP PROTECTION LLC, DEVGEN NVInventors: Pascale Feldmann, Jeffrey David Fowler, Wendy Maddelein, Nina Cromheecke, Isabelle Maillet
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Publication number: 20180200281Abstract: Disclosed are double stranded RNA molecules that are toxic to coleopteran insects. In particular, interfering RNA molecules capable of interfering with pest target genes and that are toxic to the target pest are provided. Further, methods of making and using the interfering RNA, for example in transgenic plants or as the active ingredient in a composition, to confer protection from insect damage are disclosed.Type: ApplicationFiled: August 1, 2017Publication date: July 19, 2018Applicant: SYNGENTA PARTICIPATIONS AGInventors: Kevin V. Donohue, Yann Naudet, Pascale Feldmann, Lies Degrave, Isabelle Maillet
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Patent number: 6080700Abstract: Ethephon-based composition for the regulation of plant growth containing in addition to ethephon, at least one product or adjuvant the chemical structure of which contains at least two acid functions selected from carboxylic acid type of formula (--COOH) and phosphonic acid type of formula (--PO.sub.3 H.sub.2), at least one of these acid functions being the (--PO.sub.3 H.sub.2) function.Type: GrantFiled: September 24, 1997Date of Patent: June 27, 2000Assignee: CFPI AgroInventors: Joseph Schapira, Jacques Vincent, Jacques Schild, Isabelle Maillet
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Patent number: 5716902Abstract: Herbicidal compositions based on aminotriazole comprising, besides the usual constituents, adjuvants and/or supports, on the one hand aminotriazole and on the other hand a proportion by weight with respect to the aminotriazole from about 1 to about 14.3%, preferably from 2.5 to 4% and, still more preferably, of about 3% of at least one triazinone of formula ##STR1## wherein R represents a linear or branched alkyl radical comprising from 1 to 4 carbon atoms, the proportion of triazinone in a given composition being selected taking into account the fact that the said composition should provide per hectare an amount of triazinone lower than 300 g, preferably lower than 200 g and still more preferably lower than or equal to 100 g.Herbicidal treatment implementing these compositions.Type: GrantFiled: May 22, 1996Date of Patent: February 10, 1998Assignee: CFPI ACROInventors: Joseph Schapira, Isabelle Maillet, Gerard Sergent