Abstract: A dental X-ray apparatus of the conical-beam digitized-tomography type includes: an X-ray generator emitting an X-ray beam towards an object and provided with a collimation element for collimating the emitted beam; an X-ray sensor having an active surface arranged opposite the generator; wherein the generator and the sensor can rotate simultaneously about a rotation axis, the sensor being oriented so that a longitudinal axis extending from the generator to the sensor through the rotation axis is perpendicular to the active surface of the sensor, the center of the sensor being transversally offset relative to the projection of the axis on the sensor's active surface, the arrangement of the collimation element and the sensor thus offset defining that the collimated beam illuminates the sensor's active surface while leaving a peripheral area of the surface that is faintly illuminated by the collimated beam relative to the rest of the active surface.

Abstract: The present invention relates to a method for identifying compounds that modulate cholesterol metabolism by detecting enzyme activities involved in the synthesis or catabolism of cholesterol. Said method enables the lethal risk for mammalian cells when the cholesterol level decreases to be avoided, due to the use of genetically modified yeasts, the survival of which is not strictly dependent upon the cholesterol production.

Abstract: A dental X-ray apparatus of the conical-beam digitized-tomography type includes: an X-ray generator emitting an X-ray beam towards an object and provided with a collimation element for collimating the emitted beam; an X-ray sensor having an active surface arranged opposite the generator; wherein the generator and the sensor can rotate simultaneously about a rotation axis, the sensor being oriented so that a longitudinal axis extending from the generator to the sensor through the rotation axis is perpendicular to the active surface of the sensor, the center of the sensor being transversally offset relative to the projection of the axis on the sensor's active surface, the arrangement of the collimation element and the sensor thus offset defining that the collimated beam illuminates the sensor's active surface while leaving a peripheral area of the surface that is faintly illuminated by the collimated beam relative to the rest of the active surface.

Abstract: A dental X-ray apparatus of the conical-beam digitized-tomography type includes: an X-ray generator emitting an X-ray beam towards an object and provided with a collimation element for collimating the emitted beam; an X-ray sensor having an active surface arranged opposite the generator; wherein the generator and the sensor can rotate simultaneously about a rotation axis, the sensor being oriented so that a longitudinal axis extending from the generator to the sensor through the rotation axis is perpendicular to the active surface of the sensor, the center of the sensor being transversally offset relative to the projection of the axis on the sensor's active surface, the arrangement of the collimation element and the sensor thus offset defining that the collimated beam illuminates the sensor's active surface while leaving a peripheral area of the surface that is faintly illuminated by the collimated beam relative to the rest of the active surface.

Abstract: The present invention relates to novel compounds and their pharmaceutical or diagnostic use, or use as a pharmacological target. More particularly, the present invention describes the identification of partners of the FE65 protein and the use of these partners, or of any compound which is capable of modulating, at least partially, their interaction with FE65, for regulating the activity of FE65, and in particular the phenomenon of intracellular transport or of endocytosis of the APP.

Abstract: The present invention relates to novel compounds and their pharmaceutical or diagnostic use, or use as a pharmacological target. More particularly, the present invention describes the identification of partners of the FE65 protein and the use of these partners, or of any compound which is capable of modulating, at least partially, their interaction with FE65, for regulating the activity of FE65, and in particular the phenomenon of intracellular transport or of endocytosis of the APP.

Abstract: The present invention relates to novel compounds and their pharmaceutical or diagnostic use, or use as a pharmacological target. More particularly, the present invention describes the identification of partners of the FE65 protein and the use of these partners, or of any compound which is capable of modulating, at least partially, their interaction with FE65, for regulating the activity of FE65, and in particular the phenomenon of intracellular transport or of endocytosis of the APP.

Abstract: Provided herein are novel polypeptides that are derived from human JNK3 proteins, variants of such polypeptides, their corresponding nucleotide sequences, and their uses.

Abstract: Provided herein are novel polypeptides that are derived from human JNK3 proteins, variants of such polypeptides, their corresponding nucleotide sequences, and their uses.

Abstract: The present invention relates to novel compounds and their pharmaceutical or diagnostic use, or use as a pharmacological target. More particularly, the present invention describes the identification of partners of the FE65 protein and the use of these partners, or of any compound which is capable of modulating, at least partially, their interaction with FE65, for regulating the activity of FE65, and in particular the phenomenon of intracellular transport or of endocytosis of the APP.