Patents by Inventor Isaias Prado

Isaias Prado has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stable protein compositions and methods of their use
    Patent number: 11583584
    Abstract: The present invention is directed to compositions and methods for stabilizing a protein without a surfactant. The present invention is further directed to compositions comprising a protein and at least one excipient selected from the group consisting of hindered amines, anionic aromatics, functionalized amino acids, oligopeptides, low molecular weight aliphatic polyacids, zwitterions, phospholipids, cyclodextrins, polyethylene glycols, gelatins, urea, ethanol, glycerin, dextran, xanthan gum, 2-(2-ethoxyethoxy)ethanol, hydroxypropyl cellulose, propylene glycol, a short-chain organic acid, deoxycholate, sodium nitrate, sodium sulfate, proline and lysine.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: February 21, 2023
    Assignee: Coherus Biosciences, Inc.
    Inventors: Jun Liu, Mark Manning, Isaias Prado
  • Method of filling a container with no headspace
    Patent number: 11576971
    Abstract: The present invention is directed to methods for filling a container wherein the filled container has no headspace. The present invention is further directed to methods for stabilizing an aqueous drug substance solution by filling a container with the aqueous drug substance solution wherein the filled container has no headspace. The present invention is further directed to methods for detecting headspace in a container.
    Type: Grant
    Filed: June 17, 2021
    Date of Patent: February 14, 2023
    Assignee: Coherus Biosciences, Inc.
    Inventors: John Ogez, Jun Liu, Wenchang Ji, Patrick Daniel Begley, Isaias Prado, Mark Manning
  • METHOD OF FILLING A CONTAINER WITH NO HEADSPACE
    Publication number: 20220040300
    Abstract: The present invention is directed to methods for filling a container wherein the filled container has no headspace. The present invention is further directed to methods for stabilizing an aqueous drug substance solution by filling a container with the aqueous drug substance solution wherein the filled container has no headspace. The present invention is further directed to methods for detecting headspace in a container.
    Type: Application
    Filed: June 17, 2021
    Publication date: February 10, 2022
    Inventors: John Ogez, Jun Liu, Wenchang Ji, Patrick Daniel Begley, Isaias Prado, Mark Manning
  • Anti-FGFR2 Antibody Formulations
    Publication number: 20220010020
    Abstract: This disclosure relates to a formulation of an anti-fibroblast growth factor receptor 2 (FGFR2) antibody that, in some embodiments, is capable of being stored as a liquid, for example in a ready-to-use form, and that, in some embodiments, may be administered intravenously such as by intravenous (IV) infusion.
    Type: Application
    Filed: October 4, 2019
    Publication date: January 13, 2022
    Applicant: Five Prime Therapeutics, Inc.
    Inventors: Isaias Prado, Chin-Yi Huang
  • Method of filling a container with no headspace
    Patent number: 11071782
    Abstract: The present invention is directed to methods for filling a container wherein the filled container has no headspace. The present invention is further directed to methods for stabilizing an aqueous drug substance solution by filling a container with the aqueous drug substance solution wherein the filled container has no headspace. The present invention is further directed to methods for detecting headspace in a container.
    Type: Grant
    Filed: April 20, 2017
    Date of Patent: July 27, 2021
    Assignee: Coherus Biosciences, Inc.
    Inventors: John Ogez, Jun Liu, Wenchang Ji, Patrick Daniel Begley, Isaias Prado, Mark Manning
  • METHOD OF REDUCING IMMUNOGENICITY OF DRUG PRODUCTS
    Publication number: 20180043020
    Abstract: The present invention is directed to methods for reducing immunogenicity of a drug product, utilizing filling a container wherein the filled container has no headspace. The present invention is further directed to methods for stabilizing an aqueous drug substance solution by filling a container with the aqueous drug substance solution wherein the filled container has no headspace. The present invention is further directed to formulations of drug substances with reduced immunogenicity.
    Type: Application
    Filed: October 25, 2017
    Publication date: February 15, 2018
    Inventors: John Ogez, Jun Liu, Wenchang Ji, Patrick Daniel Begley, Isaias Prado, Mark Manning
  • METHOD OF FILLING A CONTAINER WITH NO HEADSPACE
    Publication number: 20170304445
    Abstract: The present invention is directed to methods for filling a container wherein the filled container has no headspace. The present invention is further directed to methods for stabilizing an aqueous drug substance solution by filling a container with the aqueous drug substance solution wherein the filled container has no headspace. The present invention is further directed to methods for detecting headspace in a container.
    Type: Application
    Filed: April 20, 2017
    Publication date: October 26, 2017
    Inventors: John Ogez, Jun Liu, Wenchang Ji, Patrick Daniel Begley, Isaias Prado, Mark Manning