Patents by Inventor Isao Sugiyama

Isao Sugiyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11780035
    Abstract: A solder composition of the invention contains: a flux composition containing (A) a rosin resin, (B) an activator, (C) an imidazoline compound having a phenyl group, and (D) an antioxidant; and (E) solder powder, in which the (B) component contains (B1) an organic acid, the (B1) component contains at least one selected from the group consisting of (B11) 1-hydroxy-2-naphthoic acid, 3-hydroxy-2-naphthoic acid, and 1,4-dihydroxy-2-naphthoic acid, and the (C) component is at least one selected from the group consisting of 2-phenylimidazoline and 2-benzylimidazoline.
    Type: Grant
    Filed: September 21, 2021
    Date of Patent: October 10, 2023
    Assignee: Tamura Corporation
    Inventors: Ryutaro Shimoishi, Isao Sugiyama, Daigo Ichikawa
  • Publication number: 20220097181
    Abstract: A solder composition of the invention contains: a flux composition containing (A) a rosin resin, (B) an activator, (C) an imidazoline compound having a phenyl group, and (D) an antioxidant; and (E) solder powder, in which the (B) component contains (B1) an organic acid, the (B1) component contains at least one selected from the group consisting of (B11) 1-hydroxy-2-naphthoic acid, 3-hydroxy-2-naphthoic acid, and 1,4-dihydroxy-2-naphthoic acid, and the (C) component is at least one selected from the group consisting of 2-phenylimidazoline and 2-benzylimidazoline.
    Type: Application
    Filed: September 21, 2021
    Publication date: March 31, 2022
    Inventors: Ryutaro Shimoishi, Isao Sugiyama, Daigo Ichikawa
  • Patent number: 8657915
    Abstract: The present invention provides a metal powder composed of tantalum or niobium that achieves both sinterability and fluidity and the manufacturing method thereof. The present invention also provides a tantalum or niobium powder that enables the manufacturing of an anode for a solid electrolytic capacitor in which holes are formed for a conductive polymer-containing solution to pass through, without using a hole molding material or pore forming material. Furthermore, the present invention provides an anode for a solid electrolytic capacitor that enables the manufacturing of a high-volume and low ESR solid electrolytic capacitor. The present invention further provides a manufacturing method of a metal powder that allows the manufacturing of a metal powder of a given diameter range from a raw powder at high yield, without requiring a lot of work and time.
    Type: Grant
    Filed: May 31, 2006
    Date of Patent: February 25, 2014
    Assignee: Global Advanced Metals Japan, K.K.
    Inventors: Yujiro Mizusaki, Isao Sugiyama, Hitoshi Iijima, Osamu Kubota
  • Patent number: 7846301
    Abstract: A method of production of blast furnace coke comprising drying mixed coal, then, or simultaneously with the drying, classifying it to fine-grained coal and coarse-grained coal, then adding to the fine-grained coal at a temperature of 80 to 350° C. a caking additive comprised of one or more of a heavy distillate of tar, soft pitch, and petroleum pitch, agglomerating it by hot pressing, then mixing the clumps of coal and the coarse-grained coal and charging and carbonizing the mixture in a coke oven.
    Type: Grant
    Filed: May 12, 2006
    Date of Patent: December 7, 2010
    Assignee: Nippon Steel Corporation
    Inventors: Kenji Katou, Isao Sugiyama, Yoshiaki Nakashima, Hiroshi Uematsu, Takashi Arima, Masahiko Yokomizo, Michitaka Sakaida
  • Publication number: 20090080145
    Abstract: The present invention provides a metal powder composed of tantalum or niobium that achieves both sinterability and fluidity and the manufacturing method thereof. The present invention also provides a tantalum or niobium powder that enables the manufacturing of an anode for a solid electrolytic capacitor in which holes are formed for a conductive polymer-containing solution to pass through, without using a hole molding material or pore forming material. Furthermore, the present invention provides an anode for a solid electrolytic capacitor that enables the manufacturing of a high-volume and low ESR solid electrolytic capacitor. The present invention further provides a manufacturing method of a metal powder that allows the manufacturing of a metal powder of a given diameter range from a raw powder at high yield, without requiring a lot of work and time.
    Type: Application
    Filed: May 31, 2006
    Publication date: March 26, 2009
    Inventors: Yujiro Mizusaki, Isao Sugiyama, Hitoshi Iijima, Osamu Kubota
  • Publication number: 20080190753
    Abstract: A method of production of blast furnace coke comprising drying mixed coal, then, or simultaneously with the drying, classifying it to fine-grained coal and coarse-grained coal, then adding to the fine-grained coal at a temperature of 80 to 350° C. a caking additive comprised of one or more of a heavy distillate of tar, soft pitch, and petroleum pitch, agglomerating it by hot pressing, then mixing the clumps of coal and the coarse-grained coal and charging and carbonizing the mixture in a coke oven.
    Type: Application
    Filed: May 12, 2006
    Publication date: August 14, 2008
    Inventors: Kenji Katou, Isao Sugiyama, Yoshiaki Nakashima, Hiroshi Uematsu, Takashi Arima, Masahiko Yokomizo, Michitaka Sakaida
  • Patent number: 6372914
    Abstract: The present invention provides an efficient stereoselective method for manufacturing (2S,4S)-2-[[(R)-hydroxy-(3R)-cyclic amine-3-yl]methyl]pyrrolidine-4-thiol or a salt thereof which is useful as an intermediate for the manufacture of carbapenem and also provides the intermediate. A method for manufacturing which comprises the step of reacting a compound of the formula (I): (wherein, R1 is a lower alkylsulfonyl group, an optionally substituted arylsulfonyl group or an alkylsilyl group; and R2 is a protecting group for an amino group) with a compound of the formula (II): (wherein, R3 is a substituted or unsubstituted lower alkyl group or aryl group; X is an oxygen atom or a sulfur atom; Y is an azide group or a nitro group; and m is an integer of 2 to 5).
    Type: Grant
    Filed: November 2, 2000
    Date of Patent: April 16, 2002
    Assignee: Eisai Co., Ltd.
    Inventors: Takaaki Suzuki, Isao Sugiyama, Manabu Sasho, Nobuaki Sato, Atsushi Kamada, Kazuhide Ashizawa
  • Patent number: 6218550
    Abstract: The present invention provides an efficient stereoselective method for manufacturing (2S,4S)-2-[[(R)-hydroxy-(3R)-cyclic amine-3-yl]methyl]pyrrolidine-4-thiol or a salt thereof which is useful as an intermediate for the manufacture of carbapenem and also provides the intermediate. A method for manufacturing which comprises the step of reacting a compound of the formula (I): (wherein, R1 is a lower alkylsulfonyl group, an optionally substituted arylsulfonyl group or an alkylsilyl group; and R2 is a protecting group for an amino group) with a compound of the formula (II): (wherein, R3 is a substituted or unsubstituted lower alkyl group or aryl group; X is an oxygen atom or a sulfur atom; Y is an azide group or a nitro group; and m is an integer of 2 to 5).
    Type: Grant
    Filed: November 12, 1999
    Date of Patent: April 17, 2001
    Assignee: Eisai Co., Ltd.
    Inventors: Takaaki Suzuki, Isao Sugiyama, Manabu Sasho, Nobuaki Sato, Atsushi Kamada, Kazuhide Ashizawa
  • Patent number: 6037341
    Abstract: Compounds having potent antimicrobial effects over Gram-positive bacteria and Gram-negative bacteria, a high stability to .beta.-lactamases and DHP-I and a high safety for the human body and a process for producing the same. Carbapenem compounds represented by the following general formula (I) or salts thereof: ##STR1## wherein the ring A represents a 3- to 7-membered non-aromatic ring containing at least one nitrogen atom and optionally having a substituent other than R.sup.6 ; R.sup.1 represents hydrogen or methyl; R.sup.2 and R.sup.5 are the same or different and each represents hydrogen or a protecting group of the hydroxyl group; R.sup.3 represents hydrogen or a protecting group of the carboxyl group; R.sup.4 represents hydrogen, lower alkyl or a protecting group of the amino group; R.sup.6 represents: (1) hydrogen, (2) lower alkyl, optionally substituted by an optionally protected hydroxy, carbamoyl, formimidoyl, acetimidoyl or ##STR2## wherein R.sup.7 and R.sup.
    Type: Grant
    Filed: December 18, 1996
    Date of Patent: March 14, 2000
    Assignee: Eisai Co., Ltd.
    Inventors: Nobuaki Sato, Manabu Sasho, Atsushi Kamata, Takaaki Suzuki, Isao Sugiyama, Kanemasa Katsu, Takeshi Suzuki
  • Patent number: 5741902
    Abstract: A 7-acyl-3-substituted carbamoyloxy cephem compound represented by the following formula (1): ##STR1## wherein A means a --CH.dbd. or --N.dbd. group; R.sup.1 denotes a hydroxyl, lower alkoxyl, fluorine-substituted lower alkoxyl or protected hydroxyl group; R.sup.2 and R.sup.3 are the same or different and individually represent a lower alkyl, hydroxyl-substituted lower alkyl, a carbamoyl-substituted lower alkyl group or cyano-substituted lower alkyl group, R.sup.2 is a hydrogen atom and R.sup.3 is a lower alkoxyl or alkyl group optionally substituted by one or more halogen atoms, or the group ##STR2## means a 4-6 membered heterocyclic group, which contains one nitrogen atom, or a morpholino group, said heterocyclic group or morpholino group being optionally substituted by one or more lower alkyl, hydroxyl and/or hydroxyl-substituted lower alkyl groups; and R.sup.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: April 21, 1998
    Assignee: Eisai Co., Ltd.
    Inventors: Shigeto Negi, Motosuke Yamanaka, Kanemasa Katsu, Isao Sugiyama, Yuuki Komatu, Atsushi Kamata, Akihiko Tsuruoka, Yoshimasa Machida
  • Patent number: 5604217
    Abstract: A 7-acyl-3-substituted carbamoyloxy cephem compound represented by the following formula (1): ##STR1## wherein A means a --CH.dbd. or --N.dbd. group; R.sup.1 denotes a hydroxyl, lower alkoxyl, fluorine-substituted lower alkoxyl or protected hydroxyl group; R.sup.2 and R.sup.3 are the same or different and individually represent a lower alkyl, hydroxyl-substituted lower alkyl, a carbamoyl-substituted lower alkyl group or cyano-substituted lower alkyl group, R.sup.2 is a hydrogen atom and R.sup.3 is a lower alkoxyl or alkyl group optionally substituted by one or more halogen atoms or the group ##STR2## means a 4-6 membered heterocyclic group, which contains one nitrogen atom, or a morpholino group, said heterocyclic group or morpholino group being optionally substituted by one or more lower alkyl, hydroxyl and/or hydroxyl-substituted lower alkyl groups; and R.sup.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: February 18, 1997
    Assignee: Eisai Co., Ltd.
    Inventors: Shigeto Negi, Motosuke Yamanaka, Kanemasa Katsu, Isao Sugiyama, Yuuki Komatu, Atsushi Kamata, Akihiko Tsuruoka, Yoshimasa Machida
  • Patent number: 5587473
    Abstract: A 7-acyl-3-substituted carbamoyloxy cephem compound represented by the following formula (1): ##STR1## wherein A means a --CH.dbd. or --N.dbd. group; R.sup.1 denotes a hydroxyl, lower alkoxyl, fluorine-substituted lower alkoxyl or protected hydroxyl group; R.sup.2 and R.sup.3 are the same or different and individually represent a lower alkyl, hydroxyl-substituted lower alkyl, a carbamoyl-substituted lower alkyl group or cyano-substituted lower alkyl group, R.sup.2 is a hydrogen atom and R.sup.3 is a lower alkoxyl or alkyl group optionally substituted by one or more halogen atoms, or the group ##STR2## means a 4-6 membered heterocyclic group, which contains one nitrogen atom, or a morpholino group, said heterocyclic group or morpholino group being optionally substituted by one or more lower alkyl, hydroxyl and/or hydroxyl-substituted lower alkyl groups; and R.sup.
    Type: Grant
    Filed: June 27, 1996
    Date of Patent: December 24, 1996
    Assignee: Eisai Co., Ltd.
    Inventors: Shigeto Negi, Motosuke Yamanaka, Kanemasa Katsu, Isao Sugiyama, Yuuki Komatu, Atsushi Kamata, Akihiko Tsuruoka, Yoshimasa Machida
  • Patent number: 5563265
    Abstract: A 7-acyl-3-substituted carbamoyloxy cephem compound represented by the following formula (1): ##STR1## wherein A means a --CH.dbd. or --N.dbd. group; R.sup.1 denotes a hydroxyl, lower alkoxyl, fluorine-substituted lower alkoxyl or protected hydroxyl group; R.sup.2 and R.sup.3 are the same or different and individually represent a lower alkyl, hydroxyl-substituted lower alkyl, a carbamoyl-substituted lower alkyl group or cyano-substituted lower alkyl group, R.sup.2 is a hydrogen atom and R.sup.3 is a lower alkoxyl or alkyl group optionally substituted by one or more halogen atoms, or the group ##STR2## means a 4-6 membered heterocyclic group, which contains one nitrogen atom, or a morpholino group, said heterocyclic group or morpholino group being optionally substituted by one or more lower alkyl, hydroxyl and/or hydroxyl-substituted lower alkyl groups; and R.sup.
    Type: Grant
    Filed: February 23, 1995
    Date of Patent: October 8, 1996
    Assignee: Eisai Co., Ltd.
    Inventors: Shigeto Negi, Motosuke Yamanaka, Kanemasa Katsu, Isao Sugiyama, Yuuki Komatu, Atsushi Kamata, Akihiko Tsuruoka, Yoshimasa Machida
  • Patent number: 5559225
    Abstract: A 7-acyl-3-substituted carbamoyloxy cephem compound represented by the following formula (1): ##STR1## wherein A means a --CH.dbd. or --N.dbd. group; R.sup.1 denotes a hydroxyl, lower alkoxyl or protected hydroxyl group; R.sup.2 and R.sup.3 are the same or different and individually represent a lower alkyl, hydroxyl-substituted lower alkyl, a carbamoyl-substituted lower alkyl group or cyano-substituted lower alkyl group, R.sup.2 is a hydrogen atom and R.sup.3 is a lower alkoxyl or alkyl group optionally substituted by one or more halogen atoms, or the group ##STR2## means a 4-6 membered heterocyclic group, which contains one nitrogen atom, or a morpholino group, said heterocyclic group or morpholino group being optionally substituted by one or more lower alkyl, hydroxyl and/or hydroxyl-substituted lower alkyl groups; and R.sup.
    Type: Grant
    Filed: March 14, 1994
    Date of Patent: September 24, 1996
    Assignee: Eisai Co., Ltd.
    Inventors: Shigeto Negi, Motosuke Yamanaka, Kanemasa Katsu, Isao Sugiyama, Yuuki Komatu, Atsushi Kamata, Akihiko Tsuruoka, Yoshimasa Machida
  • Patent number: 5373000
    Abstract: A cephalosporin derivative represented by the formula: ##STR1## wherein R.sub.1 represents a lower alkyl group, and A is selected from: a group of the following formula: ##STR2## where R.sub.2 and R.sub.3 are the same or different lower alkyl group, R.sub.4 represents a substituted lower alkyl or amino group;a group which may be substituted and which is represented by the following formula: ##STR3## where R.sub.5 represents a lower alkyl group; or a group of the following formula: ##STR4## where R.sub.5 is as defined above, R.sub.6 represents a hydroxyl lower alkyl or carboxyl group, or its pharmacologically acceptable salt, and a process for preparing the same, as well as an antibacterial agent containing the same.
    Type: Grant
    Filed: April 1, 1992
    Date of Patent: December 13, 1994
    Assignee: Eisai Co., Ltd.
    Inventors: Yoshimasa Machida, Takashi Kamiya, Shigeto Negi, Toshihiko Naito, Yuuki Komatu, Seiichiro Nomoto, Isao Sugiyama, Hiroshi Yamauchi
  • Patent number: 5151417
    Abstract: 3-Substituted vinyl cephalosporin derivatives represented by the following formula: ##STR1## wherein R.sup.1 represents a hydroxyl or lower alkoxyl group, X represents a nitrogen atom or a group represented by the formula --CH.dbd., R.sup.2 represents a carboxyl group or a carboxyl group protected with a protecting group, and R.sup.3 is as defined herein, and pharmaceutically acceptable salts thereof are potent antibacterial agents. Processes for their preparation, intermediates in such processes, and antibacterial compositions containing them as active ingredients are also described.
    Type: Grant
    Filed: July 10, 1990
    Date of Patent: September 29, 1992
    Assignee: Eisai Co., Ltd.
    Inventors: Manabu Sasho, Hiroshi Yamauchi, Motosuke Yamanaka, Takaharu Nakamura, Kanemasa Katsu, Isao Sugiyama, Yuuki Komatu, Shigeto Negi
  • Patent number: 5128465
    Abstract: A cephem derivative represented by the following formula: ##STR1## wherein R.sub.1 means a fluorine-substituted lower alkyl and A.sub.1 denotes a cyclic or acyclic ammonio group, or a non-toxic salt thereof, is prepared by reacting a compound represented by the following formula: ##STR2## wherein A.sub.1 has the same meaning as defined above, with another compound represented by the following formula: ##STR3## wherein R.sub.1 has the same meaning as defined above, and if necessary, removing the protecting groups.
    Type: Grant
    Filed: January 22, 1990
    Date of Patent: July 7, 1992
    Assignee: Eisai Co., Ltd.
    Inventors: Takashi Kamiya, Toshihiko Naito, Yuuki Komatu, Yasunobu Kai, Takaharu Nakamura, Manabu Sasho, Shigeto Negi, Isao Sugiyama, Kanemasa Katsu, Hiroshi Yamauchi
  • Patent number: 5089491
    Abstract: A 3-propenylcephem derivative of the following formula: ##STR1## wherein R.sub.1 represents a fluoro-substituted lower alkyl group or a cyano-substituted lower alkyl group, and A represents a cyclic or an acylic ammonio group, or a pharmaceutically acceptable salt thereof, exhibiting excellent anti-bacterial activities against both Gram-positive bacteria and Gram-negative bacteria; Process for the preparation thereof; Anti-bacterial composition; Intermediate for the 3-propenylcephem derivative; and Process for the preparation of the intermediate.
    Type: Grant
    Filed: January 11, 1990
    Date of Patent: February 18, 1992
    Assignee: Eisai Co., Ltd.
    Inventors: Takashi Kamiya, Toshihiko Naito, Shigeto Negi, Yuuki Komatu, Yasunobu Kai, Takaharu Nakamura, Isao Sugiyama, Yoshimasa Machida, Seiichiro Nomoto, Kyosuke Kitoh, Kanemasa Katsu, Hiroshi Yamauchi
  • Patent number: 5022947
    Abstract: The invention provides a means to prepare a highly water-resistant printed material by the ink-jet printing method despite the water-solubility of the dye in the aqueous ink used in the ink-jet printing method. The inventive method comprises: overcoating the surface of the sheet material, which has a water-absorptive surface layer with receptivity of the aqueous ink and printed by the ink-jet printing method, with a curable polyisocyanate compound and bringing the overcoating layer under a condition capable of curing the polyisocyanate compound.
    Type: Grant
    Filed: June 5, 1990
    Date of Patent: June 11, 1991
    Assignee: Shin-Etsu Polymer Co., Ltd.
    Inventors: Masamitsu Hasegawa, Satoshi Tamura, Isao Sugiyama, Takashi Wakashima
  • Patent number: 5010188
    Abstract: Described herein is a cephem derivative represented by the general formula: ##STR1## wherein n stands for 1 or 2, Y stands for CH or nitrogen atom, R.sub.1 represents a lower hydrocarbon group or a carboxyl-substituted, a carbamoyl-substituted, or a cyclopropyl-substituted lower alkyl group, and R.sub.2 denotes hydroxyl group, a lower alkyl group, a hydroxy-substituted lower alkyl group, or carbamoyl group. The derivative is useful as an antibacterial composition. Also described herein are processes for the production of the derivative, antibacterial composition, intermediate of the derivative and process for the production thereof.
    Type: Grant
    Filed: March 16, 1988
    Date of Patent: April 23, 1991
    Assignee: Eisai Co., Ltd.
    Inventors: Hiroshi Yamauchi, Isao Sugiyama, Isao Saito, Seiichiro Nomoto, Takashi Kamiya, Yoshimasa Machida, Shigeto Negi