Abstract: A computer-implemented method is disclosed for candidate antibody exploration. The method includes receiving sequence reads from a sequencing system, wherein each sequence read comprises a target gene for expressing a candidate antibody, wherein each sequence read is associated with a binding affinity to a target antigen. The method includes generating a sequence representation for each sequence read, representing the amino acid sequences of the sequence read. The method includes training a binding affinity prediction model with the sequence representations and the binding affinities. The method includes generating a synthetic candidate sequence read that is different from the sequence reads. The method includes generating a sequence representation for the synthetic candidate sequence read.

Abstract: Disclosed herein is a system configured to implement a service worker capable of serving multiple single page applications (SPAs) that are hosted in the same uniform resource locator (URL) space (e.g., a domain within which the SPAs are hosted). Accordingly, the defined scope of the service worker is no longer bound by only one SPA, but rather by a root directory of a web site that hosts multiple SPAs. Since the service worker described herein serves multiple SPAs, the service worker implements an approach to ensure that a correct application controller corresponding to the SPA that hosts a URL is invoked. To do this, the service worker is configured to leverage a router and a routing table to associate a URL included in a request from a browser with the correct application controller corresponding to the SPA that hosts the URL for which the request is sent.

Abstract: Disclosed herein is a system configured to implement a service worker capable of serving multiple single page applications (SPAs) that are hosted in the same uniform resource locator (URL) space (e.g., a domain within which the SPAs are hosted). Accordingly, the defined scope of the service worker is no longer bound by only one SPA, but rather by a root directory of a web site that hosts multiple SPAs. Since the service worker described herein serves multiple SPAs, the service worker implements an approach to ensure that a correct application controller corresponding to the SPA that hosts a URL is invoked. To do this, the service worker is configured to leverage a router and a routing table to associate a URL included in a request from a browser with the correct application controller corresponding to the SPA that hosts the URL for which the request is sent.