Patents by Inventor Isidro Angelo E. Zarraga

Isidro Angelo E. Zarraga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7923560
    Abstract: The present invention provides immune response modifiers (IRMs) associated with (typically, attached to, and preferably, covalently attached to) macromolecular support materials. The IRM compounds in such IRM-support complexes retain biological activity. Such attachment of an IRM to a macromolecular support material provides for the localized biological activity of the IRM.
    Type: Grant
    Filed: April 9, 2004
    Date of Patent: April 12, 2011
    Assignee: 3M Innovative Properties Company
    Inventors: Paul D. Wightman, Isidro Angelo E. Zarraga, Naiyong Jing, Jie J. Liu
  • Publication number: 20100028381
    Abstract: The present invention provides pharmaceutical compositions that include an IRM-PEG complex and an antigen, formulated together in a thermoresponsive gel. In another aspect, the present invention also provides a method of eliciting an antigen-specific immune response in a subject. Generally, the method includes administering to the subject a pharmaceutical composition comprising an IRM-PEG complex and an antigen, formulated together in a thermoresponsive gel, in an amount effective to generate an immune response in the subject against the antigen. In yet another aspect, the present invention also provides a method of treating a condition in a subject. Generally, the method includes administering to the subject a pharmaceutical composition comprising an IRM-PEG complex and an antigen, formulated together in a thermoresponsive gel, in an amount effective to ameliorate at least one symptom or clinical sign of the condition.
    Type: Application
    Filed: June 18, 2007
    Publication date: February 4, 2010
    Applicant: 3M INNOVATIVE PROPERTIES COMPANY
    Inventors: Kevin S. Gorski, Ronnie Ortiz, James D. Stoesz, Isidro Angelo E. Zarraga
  • Patent number: 7427629
    Abstract: The present invention provides immunostimulatory compositions that include an immune response modifier portion paired with an antigenic portion.
    Type: Grant
    Filed: August 14, 2003
    Date of Patent: September 23, 2008
    Assignee: 3M Innovative Properties Company
    Inventors: Ross M. Kedl, George W. Griesgraber, Isidro Angelo E. Zarraga, Paul D. Wightman
  • Patent number: 7238269
    Abstract: A device includes a substrate having first and second major surfaces and a hub that defines an axis of rotation for the substrate, and an unvented channel having a plurality of connected compartments. Methods for using devices of the invention are also disclosed.
    Type: Grant
    Filed: July 1, 2003
    Date of Patent: July 3, 2007
    Assignee: 3M Innovative Properties Company
    Inventors: Samuel J. Gason, William Bedingham, Bathsheba E. Chong Conklin, Patrick L. Coleman, Peter D. Ludowise, Isidro Angelo E. Zarraga
  • Publication number: 20040258698
    Abstract: The present invention provides immune response modifiers (IRMs) associated with (typically, attached to, and preferably, covalently attached to) macromolecular support materials. The IRM compounds in such IRM-support complexes retain biological activity. Such attachment of an IRM to a macromolecular support material provides for the localized biological activity of the IRM.
    Type: Application
    Filed: April 9, 2004
    Publication date: December 23, 2004
    Inventors: Paul D. Wightman, Isidro Angelo E. Zarraga, Naiyong Jing, Jie J. Liu
  • Publication number: 20040091491
    Abstract: The present invention provides immunostimulatory compositions that include an immune response modifier portion paired with an antigenic portion.
    Type: Application
    Filed: August 14, 2003
    Publication date: May 13, 2004
    Applicant: 3M Innovative Properties Company
    Inventors: Ross M. Kedl, George W. Griesgraber, Isidro Angelo E. Zarraga