Patents by Inventor Ismail Syed

Ismail Syed has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lipids that increase insulin sensitivity and methods of using the same
    Patent number: 11174216
    Abstract: The invention provides, inter alia, fatty acyl hydroxy fatty acid (FAHFA; a novel class of estolide-related molecules) and diagnostic and treatment methods for a variety of disorders—including diabetes-related disorders, Metabolic Syndrome, polycyctic ovarian syndrome, cancer, and inflammatory disorders—using them; as well as methods of screening for additional compounds that are useful in treating these disorders and/or that modulate FAHFA levels, FAHFA-mediated signaling, and FAHFA-mediated biological effects.
    Type: Grant
    Filed: March 8, 2018
    Date of Patent: November 16, 2021
    Assignees: Beth Israel Deaconess Medical Center, Inc., President and Fellows of Harvard College
    Inventors: Barbara B. Kahn, Mark A. Herman, Alan Saghatelian, Edwin Homan, Mark M. Yore, Ismail Syed, Pedro M. M. Moraes Vieira
  • Fatty acid esters of hydroxy fatty acids (FAHFAs) for use in the treatment of type 1 diabetes
    Patent number: 11013711
    Abstract: Provided herein are methods for treating type 1 diabetes and its sequelae (e.g., cardiovascular, renal or neurologic diseases for which type 1 diabetes is a risk factor) in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a fatty acid ester of a hydroxy fatty acid (FAHFA), or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: June 9, 2017
    Date of Patent: May 25, 2021
    Assignees: Beth Israel Deaconess Medical Center, Inc., Salk Institute for Biological Studies, President and Fellows of Harvard College
    Inventors: Barbara B. Kahn, Alan Saghatelian, Ismail Syed
  • Fatty Acid Esters Of Hydroxy Fatty Acids (FAHFAs) For Use In The Treatment Of Type 1 Diabetes
    Publication number: 20190151276
    Abstract: Provided herein are methods for treating type 1 diabetes and its sequelae (e.g., cardiovascular, renal or neurologic diseases for which type 1 diabetes is a risk factor) in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a fatty acid ester of a hydroxy fatty acid (FAHFA), or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: June 9, 2017
    Publication date: May 23, 2019
    Inventors: Barbara B. Kahn, Alan Saghatelian, Ismail Syed
  • Lipids That Increase Insulin Sensitivity And Methods Of Using The Same
    Publication number: 20180194714
    Abstract: The invention provides, inter alia, fatty acyl hydroxy fatty acid (FAHFA; a novel class of estolide-related molecules) and diagnostic and treatment methods for a variety of disorders—including diabetes-related disorders, Metabolic Syndrome, polycyctic ovarian syndrome, cancer, and inflammatory disorders—using them; as well as methods of screening for additional compounds that are useful in treating these disorders and/or that modulate FAHFA levels, FAHFA-mediated signaling, and FAHFA-mediated biological effects.
    Type: Application
    Filed: March 8, 2018
    Publication date: July 12, 2018
    Inventors: Barbara B. Kahn, Mark A. Herman, Alan Saghatelian, Edwin Homan, Mark M. Yore, Ismail Syed, Pedro M.M. Moraes Vieira
  • Cosmetic Composition Containing A Protease Activator
    Publication number: 20080050331
    Abstract: An exfoliation composition comprising a protease activator such as a chestnut extract, at least one exfoliator and a cosmetically acceptable vehicle, and methods of use thereof.
    Type: Application
    Filed: August 23, 2006
    Publication date: February 28, 2008
    Inventors: Paolo Giacomoni, Peter Lentini, Rose Marie Sparacio, Ismail Syed
  • Compositions containing internally activated antioxidant
    Publication number: 20050214242
    Abstract: The present invention provides a method of activating a heat-activated component by an internal source of heat. As a result of an exothermic reaction between a combination of a heat-generating component and the heat-activated component, a source of heat is created within the composition without the use of an external heating source such as a hair dryer or exposure to the sun. The heat-generating component provides a heat release that triggers the activity of the heat-activated component. The compositions of the present invention are self-contained systems for generating heat to trigger the heat-activated component, and therefore, do not rely upon an external source of heat to affect the heat-activated component.
    Type: Application
    Filed: January 25, 2005
    Publication date: September 29, 2005
    Inventors: Fatemeh Mohammadi, Anna Czarnota, Ismail Syed