Patents by Inventor Israel Metal
Israel Metal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150080256Abstract: A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. Luminescent samples are placed in a plurality of sample wells in a tray, and the tray is placed in a visible-light impervious chamber containing a charge coupled device camera. The samples may be injected in the wells, and the samples may be injected with buffers and reagents, by an injector. In the chamber, light from the luminescent samples pass through a collimator, a Fresnel field lens, a filter, and a camera lens, whereupon a focused image is created by the optics on the charge-coupled device (CCD) camera. The use of a Fresnel field lens, in combination with a collimator and filter, reduces crosstalk between samples below the level attainable by the prior art. Preferred embodiments of the luminescence detecting apparatus and method disclosed include central processing control of all operations, multiple wavelength filter wheel, and robot handling of samples and reagents.Type: ApplicationFiled: October 15, 2014Publication date: March 19, 2015Inventors: Michael R. GAMBINI, Jeff A. Levi, John C. Voyta, John G. Atwood, Bruce E. DeSimas, II, Edward J. Lakatos, Israel Metal, George Sabak, Yongdong Wang
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Patent number: 8865473Abstract: A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. A detecting apparatus may be configured so that light from luminescent samples pass through a collimator, a first lens, a filter, and a camera lens, whereupon an image is created by the optics on the charge-coupled device (CCD) camera. The detecting apparatus may further include central processing control of all operations, multiple wavelength filter wheel, and/or a robot for handling of samples and reagents.Type: GrantFiled: August 13, 2012Date of Patent: October 21, 2014Assignee: Applied Biosystems, LLCInventors: Michael Gambini, Jeff Levi, John Voyta, Bruce E. DeSimas, II, Edward Lakatos, Israel Metal, George Sabak, Yongdong Wang, Susan A. Atwood-Stone
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Publication number: 20120309103Abstract: A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. Luminescent samples are placed in a plurality of sample wells in a tray, and the tray is placed in a visible-light impervious chamber containing a charge coupled device camera. The samples may be injected in the wells, and the samples may be injected with buffers and reagents, by an injector. In the chamber, light from the luminescent samples pass through a collimator, a Fresnel field lens, a filter, and a camera lens, whereupon a focused image is created by the optics on the charge-coupled device (CCD) camera. The use of a Fresnel field lens, in combination with a collimator and filter, reduces crosstalk between samples below the level attainable by the prior art. Preferred embodiments of the luminescence detecting apparatus and method disclosed include central processing control of all operations, multiple wavelength filter wheel, and robot handling of samples and reagents.Type: ApplicationFiled: August 13, 2012Publication date: December 6, 2012Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Michael Gambini, John C. Voyta, John Atwood, Susan A. Atwood-Stone, Bruce E. DeSimas, II, Edward Lakatos, Jeff Levi, Israel Metal, George Sabak, Yongdong Wang
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Patent number: 8278114Abstract: A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. A detecting apparatus may be configured so that light from luminescent samples pass through a collimator, a a first lens, a filter, and a camera lens, whereupon an image is created by the optics on the charge-coupled device (CCD) camera. The detecting apparatus may further include central processing control of all operations, multiple wavelength filter wheel, and/or a robot for handling of samples and reagents.Type: GrantFiled: March 2, 2010Date of Patent: October 2, 2012Assignee: Applied Biosystems, LLCInventors: Michael Gambini, Jeff Levi, John Voyta, John Atwood, Susan Atwood-Stone, legal representative, Bruce De Simas, Edward Lakatos, Israel Metal, George Sabak, Yongdong Wang
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Publication number: 20100248387Abstract: A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. Luminescent samples are placed in a plurality of sample wells in a tray, and the tray is placed in a visible-light impervious chamber containing a charge coupled device camera. The samples may be injected in the wells, and the samples may be injected with buffers and reagents, by an injector. In the chamber, light from the luminescent samples pass through a collimator, a Fresnel field lens, a filter, and a camera lens, whereupon a focused image is created by the optics on the charge-coupled device (CCD) camera. The use of a Fresnel field lens, in combination with a collimator and filter, reduces crosstalk between samples below the level attainable by the prior art. Preferred embodiments of the luminescence detecting apparatus and method disclosed include central processing control of all operations, multiple wavelength filter wheel, and robot handling of samples and reagents.Type: ApplicationFiled: March 2, 2010Publication date: September 30, 2010Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Michael R. Gambini, John C. Voyta, John Atwood, Susan A. Atwood-Stone, Bruce E. DeSimas, II, Edward Lakatos, Jeff Levi, Israel Metal, George Sabak, Yongdong Wang
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Patent number: 7670848Abstract: In a luminescence detecting apparatus and method for analyzing luminescent samples, luminescent samples are placed in a plurality of sample wells in a tray, and the tray is placed in a visible-light impervious chamber containing a charge coupled device camera. In the chamber, light from the luminescent samples pass through a collimator, a Fresnel field lens, an infrared filter, and a camera lens, whereupon a focused image is created by the optics on the camera. The use of an infrared filter suppresses stray IR radiation resulting from plate phosphorescence (which can result in abnormally high backgrounds and/or alteration of the image received by the camera).Type: GrantFiled: October 18, 2005Date of Patent: March 2, 2010Assignee: Applied Biosystems, LLCInventors: Michael R. Gambini, John C. Voyta, John Atwood, Susan A. Atwood-Stone, legal representative, Bruce E. DeSimas, II, Edward Lakatos, Jeff Levi, Israel Metal, George Sabak, Yongdong Wang
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Publication number: 20060088444Abstract: In a luminescence detecting apparatus and method for analyzing luminescent samples, luminescent samples are placed in a plurality of sample wells in a tray, and the tray is placed in a visible-light impervious chamber containing a charge coupled device camera. In the chamber, light from the luminescent samples pass through a collimator, a Fresnel field lens, an infrared filter, and a camera lens, whereupon a focused image is created by the optics on the camera. The use of an infrared filter suppresses stray IR radiation resulting from plate phosphorescence (which can result in abnormally high backgrounds and/or alteration of the image received by the camera).Type: ApplicationFiled: October 18, 2005Publication date: April 27, 2006Inventors: Michael Gambini, John Voyta, John Atwood, Susan Atwood Stone, Bruce DeSimas, Edward Lakatos, Jeff Levi, Israel Metal, George Sabak, Yongdong Wang
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Publication number: 20030092194Abstract: A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. Luminescent samples are placed in a plurality of sample wells in a tray, and the tray is placed in a visible-light impervious chamber containing a charge coupled device camera. The samples may be injected in the wells, and the samples may be injected with buffers and reagents, by an injector. In the chamber, light from the luminescent samples pass through a collimator, a Fresnel field lens, a filter, and a camera lens, whereupon a focused image is created by the optics on the charge-coupled device (CCD) camera. The use of a Fresnel field lens, in combination with a collimator and filter, reduces crosstalk between samples below the level attainable by the prior art. Preferred embodiments of the luminescence detecting apparatus and method disclosed include central processing control of all operations, multiple wavelength filter wheel, and robot handling of samples and reagents.Type: ApplicationFiled: December 20, 2002Publication date: May 15, 2003Inventors: Michael R. Gambini, John C. Voyta, John Atwood, Bruce E. DeSimas, Edward Lakatos, Jeff Levi, Israel Metal, George Sabak, Yongdong Wang
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Patent number: 6518068Abstract: A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. Luminescent samples are placed in a plurality of sample wells in a tray, and the tray is placed in a visible-light impervious chamber containing a charge coupled device camera. The samples may be injected in the wells, and the samples may be injected with buffers and reagents, by an injector. In the chamber, light from the luminescent samples pass through a collimator, a Fresnel field lens, a filter, and a camera lens, whereupon a focused image is created by the optics on the charge-coupled device (CCD) camera. The use of a Fresnel field lens, in combination with a collimator and filter, reduces crosstalk between samples below the level attainable by the prior art. Preferred embodiments of the luminescence detecting apparatus and method disclosed include central processing control of all operations, multiple wavelength filter wheel, and robot handling of samples and reagents.Type: GrantFiled: July 21, 2000Date of Patent: February 11, 2003Assignee: Tropix, Inc.Inventors: Michael R. Gambini, John C. Voyta, John Atwood, Bruce E. DeSimas, II, Edward Lakatos, Jeff Levi, Israel Metal, George Sabak, Yongdong Wang
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Patent number: 5552791Abstract: An apparatus and method for calibrating a plurality of sensors having a predetermined spatial distribution.Type: GrantFiled: April 7, 1995Date of Patent: September 3, 1996Assignee: Northrop Grumman CorporationInventor: Israel Metal
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Patent number: 4434369Abstract: A radiographic camera is provided having a scintillator and a plurality of photodetectors positioned to face the scintillator for providing position electrical signals. The photodetectors are disposed at different, progressively increasing, predetermined distances from a reference point to a distal point adjacent the outer periphery of a nominal field of view of the camera. The position electrical signal provided by each one of the plurality of photodetectors has an amplitude related to the distance between such one of the photodetectors and the point of impingement of radiation on the scintillator. Circuitry, responsive to a plurality of the position electrical signals, is provided for producing an extrapolated correction electrical signal, such correction electrical signal having an amplitude representative of the distance between the point of an impingement of radiation on the scintillator and a point beyond the distal point and outside of the nominal field of view of the camera.Type: GrantFiled: January 2, 1981Date of Patent: February 28, 1984Assignee: Raytheon CompanyInventor: Israel Metal
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Patent number: 4413183Abstract: A gamma camera having an array of photodetectors arranged to locate a flash of light produced by a scintillator in response to an incident gamma ray photon. A current pulse is produced by each one of the photodetectors in response to each incident gamma ray photon, the amount of charge produced by each one of such photodetectors being a measure of the portion of the energy of the photon detected by such one of the photodetectors. Each integrator produces a voltage which rises from an initial reference level, typically ground potential, to a peak level, such peak voltage level being representative of the amount of charge in the current pulse and hence the peak level of such voltage is a measure of the portion of the energy of the photon detected by such one of the photodetector. The outputs of the integrators are combined to provide X and Y coordinate location signals.Type: GrantFiled: December 29, 1980Date of Patent: November 1, 1983Assignee: Raytheon CompanyInventors: Israel Metal, Vincent Berluti, Jr.