Abstract: The invention relates to the preparation of lyophilized, absorbed polyvalent vaccines. According to the invention tetanus, diphtheria, pertussis and optionally typhus antigens concentrated to 5 to 15 doses/3 ml are adsorbed at a pH value of 3 to 6 to an insoluble carrier concentrated in the same way as the antigens, then the pH of the mixture is adjusted to a value of 5 to 6 and lyophilized together with a protective material commonly used in lyophilizing processes. Before administration the lyophilized vaccine is diluted to the concentration required by a physiological saline buffered to a pH value of 6.8 to 7 by a phosphate solution.

Abstract: A process is disclosed for automatically positioning the drill spindle over a workpiece at a predetermined location defining the bore center, wherein the shop drawing and the workpiece bore centers are defined as to their locations in different coordinate systems and wherein the invention provides for calculating and measuring steps to transform between the various coordinate systems. The invention discloses also apparatus for practicing the process by employing a controller-arithmatic unit which carries out the coordination of the plurality of logic circuits and the effecting the use of a programmed performance of the process including the teaching or updating of the program for new bores.