Patents by Inventor Ivana Gazic Smilovic

Ivana Gazic Smilovic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthetic route for the preparation of ?-amino boronic acid derivatives via substituted alk-1-ynes
    Patent number: 9315525
    Abstract: A process for producing bortezomib N-(pyrazin-2-yl)carbonyl-L-phenylalanine-L-leucine boronic acid) comprising the step of deprotecting the compound of formula XII: to yield bortezomib.
    Type: Grant
    Filed: June 18, 2010
    Date of Patent: April 19, 2016
    Assignee: Lek Pharmaceuticals D.D.
    Inventors: Ivana Gazic Smilovic, Zdenko Casar
  • Synthesis of triazolopyrimidine compounds
    Patent number: 9278972
    Abstract: The present invention relates to the field of organic synthesis and describes the synthesis of specific intermediates suitable for the preparation of triazolopyrimidine compounds such as ticagrelor.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: March 8, 2016
    Assignee: Lek Pharmaceuticals d.d.
    Inventors: Nenad Maras, Ivana Gazic Smilovic, Damjan Sterk
  • Synthesis of Triazolopyrimidine Compounds
    Publication number: 20140371449
    Abstract: The present invention relates to the field of organic synthesis and describes the synthesis of specific intermediates suitable for the preparation of triazolopyrimidine compounds such as ticagrelor.
    Type: Application
    Filed: December 20, 2012
    Publication date: December 18, 2014
    Applicant: Lek Pharmaceuticals d.d.
    Inventors: Nenad Maras, Ivana Gazic Smilovic, Damjan Sterk
  • Process for hydrogenation of halogenoalkenes without dehalogenation
    Patent number: 8785674
    Abstract: A process for preparing a compound of formula VI wherein R1 and R6 is hydrogen, substituted or unsubstituted alkyl substituted or unsubstituted aryl, or substituted or unsubstituted aralkyl; R5 is B(OR2)(OR3), or wherein R2 and R3 independently from each other represent substituted or unsubstituted alkyl, substituted or unsubstituted aryl, or substituted or unsubstituted aralkyl; or R2 and R3 cooperatively form a part of a 5- to 10-membered fused or unfused ring, optionally a chiral 5- to 10-membered fused or unfused ring; X is selected from Cl, Br, I; and * indicates a chiral center; is described.
    Type: Grant
    Filed: June 18, 2010
    Date of Patent: July 22, 2014
    Assignee: Lek Pharmaceuticals D.D.
    Inventors: Ivana Gazic Smilovic, Zdenko Casar
  • NEW SYNTHETIC ROUTE FOR THE PREPARATION OF ALPHA-AMINO BORONIC ACID DERIVATIVES via SUBSTITUTED ALK-1-YNES
    Publication number: 20120231993
    Abstract: The present invention relates in general to the field of organic chemistry and in particular to the preparation of ?-amino boronic acid derivatives.
    Type: Application
    Filed: June 18, 2010
    Publication date: September 13, 2012
    Applicant: LEK PHARMACEUTICALS D.D.
    Inventors: Ivana Gazic Smilovic, Zdenko Casar
  • PROCESS FOR HYDROGENATION OF HALOGENOALKENES WITHOUT DEHALOGENATION
    Publication number: 20120220794
    Abstract: The present invention relates in general to the field of organic chemistry and in particular to the preparation of halogenoalkanes.
    Type: Application
    Filed: June 18, 2010
    Publication date: August 30, 2012
    Applicant: LEK PHARMACEUTICALS D.D.
    Inventors: Ivana Gazic Smilovic, Zdenko Casar