Abstract: Generating a robust radiotherapy treatment plan for a treatment volume, defined using a plurality of voxels, of a subject. A first and at least one second image of the treatment volume are received. A distribution of mapped doses in the first image is generated by mapping a dose defined in the at least one second image to the first image using image registration. An optimization problem is defined using at least one optimization function for a total dose, related to the radiotherapy treatment. At least one optimization function value is calculated based on at least two mapped doses in the distribution of mapped doses in the first image. A radiotherapy treatment plan is generated by optimizing the at least one optimization function value evaluated by taking into account the at least two mapped doses in the distribution of mapped doses.

Abstract: The present invention relates to a system and a method for achieving consensus between multiple parties (A, B, C) on an event and/or order of events (1 . . . 5) at high speed by verifying and voting on events by creating a voting event referencing one or multiple other events individually or as a group of events.