Abstract: A filter element (5) for separating solids from liquids or gases is described, wherein the filter element (5) has a first perforated plate (1) and a second perforated plate (2), wherein the two perforated plates (1, 2) are arranged parallel to one another and are covered by a filter covering (3). In this case, the two perforated plates (1, 2) are displaceable in the longitudinal direction relatively to one another from a non-displaced state into a displaced state, and the plates (1, 2) have spacers (4) on the mutually facing inner sides, which spacers are constructed in such a manner that the spacing (D?) between the plates (1, 2) is larger in the displaced state than in the non-displaced state (D), so that the filter covering (3) is tensioned in the displaced state of the plates (1, 2). In addition, at least one latching element (6) is provided, which fixes the plates (1, 2) to one another in the displaced state.

Abstract: A device for separating solid particles from liquids includes a pressure vessel and one or more filter element registers having filter elements disposed in suspension on a horizontal filtrate discharge pipe. Each of the filter elements is formed from a substantially flat support mesh, a completely enclosed filter medium and spacers suspended therebetween. The support mesh is formed of rolled-flat mesh pipes that are smooth on an outside of the mesh pipes and, in an interior thereof, include longitudinal webs arranged to form channels that permit filtrate to flow to the horizontal discharge pipe.

Abstract: The invention relates to method for the stepwise removal of bacteria from a fermentation broth. According to said method, the bacteria in the fermentation broth are mixed with a retention promoter mixture in a first process step and the pretreated bacteria are removed by precoat filtration in a second process step. The inventive method uses a retention promoter mixture from bentonite and polycations such as PEI or polyDADMAC and is suitable for treating large quantities of bacteria. The filter cake obtained with bentonite/PEI has a substantially improved quality.

Abstract: The method of making the clear cell lysate containing plasmid DNA from a biomass obtained in a cell culture process includes filtering the biomass obtained in the cell culture process with a filter medium in the presence of diatomaceous earth acting as a filtering agent to form a filter cake containing the biomass and the filter medium, then thermally digesting the biomass in the filter cake to form a cell lysate containing the plasmid DNA and filtering the cell lysate to form a clear filtrate. The clear filtrate contains the plasmid DNA and has a clarity characterized by an OD600 of at maximum 0.05 U/cm.

Abstract: The multiple-tube filter proposed consists of at least one perforated filter element (15) whose outside surface has grooves (2) in a spiral round it, the surface between the grooves (2) preferably curving outwards in a circular arc.

Abstract: The invention relates to a method for the integrated treatment of biomass from a cell culture process for producing clear cell lysate containing plasmid DNA. According to the invention, in a first step filtering occurs in a filter in the presence of a filtering agent. In a second step, the biomass contained in the filter cake which is obtained is thermally decomposed and the cell lysate is filtered in another step. The obtained cell lysate containing plasmid DNA is characterised by a clarity of OD600 of at a maximum of 0.05 E/cm and which is suitable for cloning, transformation, transfection, microinjection in cells, gene therapy, DNA vaccination and/or for polymerase chain reaction (PCR).

Abstract: A candle filter element adapted to be located inside a pressure vessel and fixed in a hanging position to a collector tube for aseptic and/or sterile filtration of liquids, has a coupling with conical upper coupling part and a conical lower coupling part, with the conical upper coupling part provided with a rinsing opening and a pair of cams.

Abstract: The filter element for use in a container includes a central pipe (2) closed along its length and also provided with an opening at a lower end thereof; a cylinder surrounding this central pipe in a concentric manner and having a closable lower end, the closable lower end of the cylinder projecting beyond the lower end of the central pipe and being provided with a base; and at least two cylindrical filter means (1), which are arranged radially and symmetrically with respect to the cylinder and which communicate with the cylinder, and a group of connecting pipes, each of the cylindrical filter means being connected by one of the pipes with the cylinder.

Abstract: A filter candle element which is mounted in depending manner in a pressure container has a support body and a filter tissue which covers the support body and has at least one impermeable portion so as to prevent the depositing of a continuous filter cake. Through provision of a plurality of impermeable portions, the filter cake is divided into several pieces which do not obstruct their removal. The impermeable portions are obtained by spraying of synthetic material onto the filter tissue. These filter candle elements are especially suitable for alluvial filters of large dimensions.

Abstract: An arrangement for fastening filter candles and filter apparatus provided therewith includes a collecting pipe which is composed of several T-shaped pipe pieces. Each of the pipe pieces has a substantially horizontal portion and extending therefrom a second portion which has a free end part provided with a groove. Each of the filter candles has an upper part provided with a flange portion which is engageable into the groove to obtain a tight attachment of the filter candle to the collecting pipe.