Patents by Inventor Iwona Lozinska

Iwona Lozinska has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMIDAZO[1,2-A]PYRAZINE MODULATORS OF THE ADENOSINE A2A RECEPTOR
    Publication number: 20200369665
    Abstract: The present invention relates to the compound of formula (I) and salts, stereoisomers, tautomers, isotopologues, or N-oxides thereof. The present invention is further concerned with the use of such a compound or salt, stereoisomer, tautomer, isotopologues, or N-oxide thereof as medicament and a pharmaceutical composition comprising said compound.
    Type: Application
    Filed: June 29, 2018
    Publication date: November 26, 2020
    Applicant: RYVU THERAPEUTICS S.A.
    Inventors: Aneta BOBOWSKA (NÉE WITKOWSKA), Michal GALEZOWSKI, Mateusz NOWAK, Claude COMMANDEUR, Joanna SZEREMETA-SPISAK, Marcin NOWOGRODZKI, Alicja OBARA, Anna DZIELAK, Iwona LOZINSKA, Marcelina DUDEK (NÉE SEDLAK), Anita ` JANIGA, Jacek REUS, Marek WRONOWSKI, Magdalena ZASTAWNA, Adam RADZIMIERSKI, Mateusz SWIRSKI, Julian ZACHMANN, Charles-Henry FABRITIUS, Roderick Alan PORTER, Joanna FOGT
  • Hybrid cholinesterase inhibitors
    Patent number: 8841453
    Abstract: The invention relates to novel hybrid cholinesterase inhibitors containing the melatonin or its oxidation products unit and tetrahydroacridine unit linked via a carbamate bond. Due to the high selectivity of action, which is expressed with high ratio of IC50 for acetylcholinesterase inhibition to IC50 for butyrylcholinesterase inhibition ([IC50(AChE)]/[IC50(BChE)]), the novel compounds may be used in relief and/or treatment of the neurodegenerative diseases, among them the Alzheimer's disease.
    Type: Grant
    Filed: November 22, 2013
    Date of Patent: September 23, 2014
    Assignees: Uniwersytet Warszawski, Centrum Medyczne Ksztalcenia Podyplomowego
    Inventors: Anna Zawadzka, Zbigniew Czarnocki, Iwona Lozinska, Zuzanna Moleda, Miroslawa Panasiewicz
  • NOVEL HYBRID CHOLINESTERASE INHIBITORS
    Publication number: 20140080860
    Abstract: The invention relates to novel hybrid cholinesterase inhibitors containing the melatonin or its oxidation products unit and tetrahydroacridine unit linked via a carbamate bond. Due to the high selectivity of action, which is expressed with high ratio of IC50 for acetylcholinesterase inhibition to IC50 for butyrylcholinesterase inhibition ([IC50(AChE)]/[IC50(BChE)]), the novel compounds may be used in relief and/or treatment of the neurodegenerative diseases, among them the Alzheimer's disease.
    Type: Application
    Filed: November 22, 2013
    Publication date: March 20, 2014
    Applicants: CENTRUM MEDYCZNE KSZTALCENIA PODYPLOMOWEGO, UNIWERSYTET WARSZAWSKI
    Inventors: Anna Zawadzka, Zbigniew Czarnocki, Iwona Lozinska, Zuzanna Moleda, Miroslawa Panasiewicz