Abstract: The present invention provides methods and compositions for modulating cell senescence and cell proliferation using isoforms of the p53 tumor suppressor protein. The methods and compositions of the invention find use in inhibiting cancer cell growth or in generating populations of cells for tissue regeneration through the modulation of cell senescence and proliferation.

Abstract: The present invention provides methods and compositions for modulating cell senescence and cell proliferation using isoforms of the p53 tumor suppressor protein. The methods and compositions of the invention find use in inhibiting cancer cell growth or in generating populations of cells for tissue regeneration through the modulation of cell senescence and proliferation.

Abstract: The present invention provides methods and compositions for modulating cell senescence and cell proliferation using isoforms of the p53 tumor suppressor protein. The methods and compositions of the invention find use in inhibiting cancer cell growth or in generating populations of cells for tissue regeneration through the modulation of cell senescence and proliferation.

Abstract: The present invention provides methods and compositions for modulating cell senescence and cell proliferation using isoforms of the p53 tumor suppressor protein. The methods and compositions of the invention find use in inhibiting cancer cell growth or in generating populations of cells for tissue regeneration through the modulation of cell senescence and proliferation.

Abstract: This invention provides methods and compositions for increasing the efficiency of obtaining pluripotent stem cells, the method comprising expressing a 133p53 in cells that are being re-programmed to obtain pluripotent cells. The invention also provides method of inhibiting the proliferation of cancer stem cells, the method comprising suppressing expression of 133p53 in the cells.

Abstract: The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of lung cancer in never-smokers. The invention also provides methods of identifying anti-lung cancer agents.

Abstract: The present invention provides methods and compositions for modulating cell senescence and cell proliferation using isoforms of the p53 tumor suppressor protein. The methods and compositions of the invention find use in inhibiting cancer cell growth or in generating populations of cells for tissue regeneration through the modulation of cell senescence and proliferation.

Abstract: Artificial TERT promoters, which are useful for enhancing the differential expression of operably linked heterologous nucleic acid sequences, such as polypeptide cytotoxins, are disclosed herein. Methods for treating disease cells, such as cancer cells, while minimizing effects on normal, somatic cells by administering therapeutically effective amounts of heterologous nucleic acid sequences operably linked to artificial TERT promoters are provided. Kits containing artificial TERT promoters for enhancing differential expression are also provided.

Abstract: Artificial TERT promoters, which are useful for enhancing the differential expression of operably linked heterologous nucleic acid sequences, such as polypeptide cytotoxins, are disclosed herein. Methods for treating disease cells, such as cancer cells, while minimizing effects on normal, somatic cells by administering therapeutically effective amounts of heterologous nucleic acid sequences operably linked to artificial TERT promoters are provided. Kits containing artificial TERT promoters for enhancing differential expression are also provided.

Abstract: A code reader reads code specification information stored in a code list. An interference level measurer measures the interference level of a received signal despread with the code specification information read by the code reader. A threshold selector selects a code specification information corresponding to an interference level smaller than a preset threshold and stores the selected code specification information in a code candidate list. A code determiner determines the code specification information of a base station from the selected code specification information. When a new base station is added, a base station code may be automatically determined without needing a theoretical design for assigning codes to all base stations.

Abstract: A small number of users who provide high interference in the other users, such as a user transmitting a high rate signal, are selected beforehand. First, a signal of the user is demodulated to generate a replica, and a difference between a received signal and the replica is calculated, thereby canceling the interference in signals of the other users, and further improving the system capacity.

Abstract: Taking into account an optimal reception characteristic of a communication apparatus with variable directivity, the base station apparatus of the present invention has a communication apparatus with variable directivity positively accommodate a communication with a terminal in poor reception conditions, which makes it possible to reduce power of this terminal and reduce interference, thereby increasing the subscriber capacity in the system.

Abstract: Taking into account an optimal reception characteristic of a communication apparatus with variable directivity, the base station apparatus of the present invention has a communication apparatus with variable directivity positively accommodate a communication with a terminal in poor reception conditions, which makes it possible to reduce power of this terminal and reduce interference, thereby increasing the subscriber capacity in the system.

Abstract: A mobile radio system includes a base station and a plurality of mobile radio apparatuses, with each mobile radio apparatus including a control CPU for controlling the mobile radio apparatus and monitoring the state of the hardware of the mobile radio apparatus, a transmitter unit for transmitting data in the form of radio waves, and a CPU monitor unit. The control CPU regularly monitors and checks for any abnormalities in the hardware of the mobile radio apparatus, and the CPU monitor unit regularly monitors and checks for any abnormalities in the control CPU. If there is an abnormality, a disabled transmission out put acceptance signal is supplied to the transmitter unit to inhibit or suppress the output of radio waves thereby avoiding interference to the system caused by unnecessary radio wave transmission from an abnormal mobile radio apparatus.

Abstract: In a base station apparatus in a mobile communication comprising a transmitting/receiving section for each sector, a baseband processing section for each sector and a sector switch to select a connection with the transmitting/receiving section and the baseband processing section, when a handover is made, a soft handover is executed by selecting a plurality of sectors on the basis of information concerning peripheral sectors obtained from a mobile station and connecting the transmitting/receiving sections of the selected sectors and the baseband processing section with the sector switch.

Abstract: A mobile radio system includes a base station and a plurality of mobile radio apparatuses, with each mobile radio apparatus including a control CPU for controlling the mobile radio apparatus and monitoring the state of the hardware of the mobile radio apparatus, a transmitter unit for transmitting data in the form of radio waves, and a CPU monitor unit. The control CPU regularly monitors and checks for any abnormalities in the hardware of the mobile radio apparatus, the CPU monitor unit regularly monitors and checks for any abnormalities in the control CPU. If there is an abnormality, a disabled transmission output acceptance signal is supplied to the transmitter unit to inhibit or suppress the output of radio waves, thereby avoiding interference to the system caused by unnecessary radio wave transmission from an abnormal mobile radio apparatus.

Abstract: In a mobile radio communication system employing a time-division multiple transmission scheme, having a plurality of base stations and a plurality of personal stations, an arbitrary base station, when detecting a pilot signal transmitted from any master base station in the mobile radio communication system, acts as a slave base station which does not transmit its pilot signal but transmits and receives a common control signal to and from a personal station utilizing a frequency channel occupied by the pilot signal. On the other hand, when not receiving the pilot signal, the base station searches for an available frequency channel, and acts as a master base station which transmits its pilot signal on the available frequency channel to occupy the frequency channel, and transmits and receives the common control signal to and from a personal station on that frequency channel.

Abstract: In a time division multiple access mobile wireless telecommunication system, a base station has a plurality of frequencies with their priority order previously registered in a memory, selects, upon starting the operation, the frequency having the highest priority from frequencies not used by other wireless telecommunication systems, and initiates communications at the selected frequency. The base station also transmits a pilot signal representative of the priority for using the selected frequency in order to prevent other wireless telecommunication system from interrupting to use the frequency.

Abstract: A space diversity reception system which minimizes the inband amplitude and/or phase dispersion by controlling the phase shifter is described. According to the present invention, the interference waves in the two antenna outputs are combined in anti-phase condition. The phase shifter control direction is decided by the sign of the two parameters. One of them is difference between two antenna levels at the center frequency of the pass-band, and the other is the difference of the combined signal levels at the extreme edges of the pass-band. The control means comprises four detectors for detecting said levels, two subtractors for providing said level differences between them, and the control circuit for deciding the phase shifter control direction.

Abstract: A space diversity reception system which minimizes the inband amplitude and/or phase dispersion by controlling the phase shifter is described. According to the present invention, the interference waves in the two antenna outputs are combined in anti-phase condition. The phase shifter control direction is decided by the sign of the two parameters. One of them is difference between two antenna levels at the center frequency of the pass-band, and the other is the difference of the combined signal levels at the extreme edges of the pass-band. The control means comprises four detectors for detecting said levels, two subtractors for providing said level difference between them, and the control circuit for deciding the phase shifter control direction.