Patents by Inventor Izumi Nomura
Izumi Nomura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10017508Abstract: The present invention provides a compound having a PDE2A selective inhibitory action, which is useful as an agent for the prophylaxis or treatment of schizophrenia, Alzheimer's disease and the like. The present invention is a compound represented by the formula (1): wherein each symbol is as described in the specification, or a salt thereof.Type: GrantFiled: September 13, 2016Date of Patent: July 10, 2018Assignee: Takeda Pharmaceutical Company LimitedInventors: Satoshi Mikami, Shinji Nakamura, Tomoko Ashizawa, Shigekazu Sasaki, Takahiko Taniguchi, Izumi Nomura, Masanori Kawasaki
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Publication number: 20170129887Abstract: The present invention provides a compound having a PDE2A selective inhibitory action, which is useful as an agent for the prophylaxis or treatment of schizophrenia, Alzheimer's disease and the like. The present invention is a compound represented by the formula (1): wherein each symbol is as described in the specification, or a salt thereof.Type: ApplicationFiled: September 13, 2016Publication date: May 11, 2017Inventors: Satoshi MIKAMI, Shinji NAKAMURA, Tomoko ASHIZAWA, Shigekazu SASAKI, Takahiko TANIGUCHI, Izumi NOMURA, Masanori KAWASAKI
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Patent number: 9624184Abstract: The present invention relates to a compound represented by the formula (I), which is useful as an agent for the prophylaxis or treatment of epilepsy, neurodegenerative disease and the like. In the formula (I), each symbol is as defined in the specification.Type: GrantFiled: April 3, 2014Date of Patent: April 18, 2017Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITEDInventors: Tatsuki Koike, Masato Yoshikawa, Izumi Nomura, Yoshiteru Ito, Eiji Kimura, Haruhi Ando, Tomoaki Hasui, Toshiya Nishi
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Patent number: 9527841Abstract: The present invention provides a compound having a PDE2A selective inhibitory action, which is useful as an agent for the prophylaxis or treatment of schizophrenia, Alzheimer's disease and the like. The present invention is a compound represented by the formula (1): wherein each symbol is as described in the specification, or a salt thereof.Type: GrantFiled: July 12, 2013Date of Patent: December 27, 2016Assignee: Takeda Pharmaceutical Company LimitedInventors: Shinji Nakamura, Satoshi Mikami, Kawasaki Masanori, Izumi Nomura, Tomoko Ashizawa, Takahiko Taniguchi
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Patent number: 9469637Abstract: The present invention provides a compound having a PDE2A selective inhibitory action, which is useful as an agent for the prophylaxis or treatment of schizophrenia, Alzheimer's disease and the like. The present invention is a compound represented by the formula (1): wherein each symbol is as described in the specification, or a salt thereof.Type: GrantFiled: April 24, 2013Date of Patent: October 18, 2016Assignee: Takeda Pharmaceutical Company LimitedInventors: Satoshi Mikami, Shinji Nakamura, Tomoko Ashizawa, Shigekazu Sasaki, Takahiko Taniguchi, Izumi Nomura, Masanori Kawasaki
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Publication number: 20160264536Abstract: The problem of the present invention is to provide a compound having a PDE2A inhibitory action, and useful as a prophylactic or therapeutic drug for schizophrenia, Alzheimer's disease and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof.Type: ApplicationFiled: October 22, 2014Publication date: September 15, 2016Inventors: Masaki SETO, Yoshihiro BANNO, Toshihiro IMAEDA, Yuichi KAJITA, Tomoko ASHIZAWA, Masanori KAWASAKI, Shinji NAKAMURA, Satoshi MIKAMI, Izumi NOMURA, Takahiko TANIGUCHI, Shogo MARUI
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Publication number: 20160159808Abstract: A compound represented by the formula (I): wherein each symbol is as described in the SPECIFICATION, or a salt thereof has a PDE2A inhibitory action, and is useful as a prophylactic or therapeutic drug for schizophrenia, Alzheimer's disease and the like.Type: ApplicationFiled: July 23, 2014Publication date: June 9, 2016Inventors: Masanori Kawasaki, Satoshi Mikami, Shinji Nakamura, Nobuyuki Negoro, Shuhei Ikeda, Izumi Nomura, Tomoko Ashizawa, Toshihiro Imaeda, Masaki Seto, Shigekazu Sasaki, Shogo Marui, Takahiko Taniguchi
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Patent number: 9296746Abstract: The present invention provides a compound or a salt thereof useful for an agent for the prophylaxis or treatment of neurodegenerative disease and the like. The present invention relates to a compound represented by the formula wherein each symbol is as defined in the present specification, or a salt thereof.Type: GrantFiled: October 15, 2013Date of Patent: March 29, 2016Assignee: Takeda Pharmaceutical Company LimitedInventors: Tatsuki Koike, Masato Yoshikawa, Izumi Nomura, Yoshiteru Ito, Eiji Kimura, Tomoaki Hasui, Haruhi Ando, Hiromi Fukuda
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Publication number: 20160052897Abstract: The present invention relates to a compound represented by the formula (I), which is useful as an agent for the prophylaxis or treatment of epilepsy, neurodegenerative disease and the like. In the formula (I), each symbol is as defined in the specification.Type: ApplicationFiled: April 3, 2014Publication date: February 25, 2016Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITEDInventors: Tatsuki KOIKE, Masato YOSHIKAWA, Izumi NOMURA, Yoshiteru ITO, Eiji KIMURA, Haruhi ANDO, Tomoaki HASUI, Toshiya NISHI
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Publication number: 20150266872Abstract: The present invention provides a compound or a salt thereof useful for an agent for the prophylaxis or treatment of neurodegenerative disease and the like. The present invention relates to a compound represented by the formula wherein each symbol is as defined in the present specification, or a salt thereof.Type: ApplicationFiled: October 15, 2013Publication date: September 24, 2015Inventors: Tatsuki Koike, Masato Yoshikawa, Izumi Nomura, Yoshiteru Ito, Eiji Kimura, Tomoaki Hasui, Haruhi Ando, Hiromi Fukuda, Toshiya Nishi
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Publication number: 20150158863Abstract: The present invention provides a compound having a PDE2A selective inhibitory action, which is useful as an agent for the prophylaxis or treatment of schizophrenia, Alzheimer's disease and the like. The present invention is a compound represented by the formula (1): wherein each symbol is as described in the specification, or a salt thereof.Type: ApplicationFiled: July 12, 2013Publication date: June 11, 2015Applicant: Takeda Pharmaceutical Company LimitedInventors: Shinji Nakamura, Satoshi Mikami, Kawasaki Masanori, Izumi Nomura, Tomoko Ashizawa, Takahiko Taniguchi
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Publication number: 20150105373Abstract: The present invention provides a compound having a PDE2A selective inhibitory action, which is useful as an agent for the prophylaxis or treatment of schizophrenia, Alzheimer's disease and the like. The present invention is a compound represented by the formula (1): wherein each symbol is as described in the specification, or a salt thereof.Type: ApplicationFiled: April 24, 2013Publication date: April 16, 2015Inventors: Satoshi Mikami, Shinji Nakamura, Tomoko Ashizawa, Shigekazu Sasaki, Takahiko Taniguchi, Izumi Nomura, Masanori Kawasaki
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Patent number: 8916549Abstract: Provision of a compound having a serotonin 5-HT2C receptor activating action. A compound represented by the formula (I): wherein each symbol is as described in the description, or a salt thereof.Type: GrantFiled: August 3, 2010Date of Patent: December 23, 2014Assignee: Takeda Pharmaceutical Company LimitedInventors: Takahiro Matsumoto, Izumi Nomura
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Publication number: 20120196848Abstract: Provision of a compound having a serotonin 5-HT2C receptor activating action. A compound represented by the formula (I): wherein each symbol is as described in the description, or a salt thereof.Type: ApplicationFiled: August 3, 2010Publication date: August 2, 2012Inventors: Takahiro Matsumoto, Izumi Nomura
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Publication number: 20120135979Abstract: Provided is a compound having a serotonin 5-HT2C receptor activating action, useful for lower urinary tract conditions, obesity and cancer. A compound represented by the formula (I0): wherein each symbol is as defined in the specification, or a salt thereof.Type: ApplicationFiled: June 14, 2010Publication date: May 31, 2012Inventors: Shigekazu Sasaki, Tomokazu Kusumoto, Izumi Nomura, Hironobu Maezaki
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Publication number: 20100317651Abstract: Provided is a compound having a serotonin 5-HT2C receptor activating action. A compound represented by the formula (I0): wherein each symbol is as defined in the specification, or a salt thereof.Type: ApplicationFiled: June 14, 2010Publication date: December 16, 2010Inventors: Shigekazu Sasaki, Tomokazu Kusumoto, Izumi Nomura, Hironobu Maezaki
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Publication number: 20090318412Abstract: The present invention provides a tricyclic heterocyclic compound having a serotonin 5-HT2C receptor activation action and the like. A 5-HT2C receptor activator containing a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof or a prodrug thereof.Type: ApplicationFiled: July 10, 2007Publication date: December 24, 2009Inventors: Takahiro Matsumoto, Izumi Kamo, Izumi Nomura
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Publication number: 20080051418Abstract: A compound represented by the formula (I): wherein Ar is an optionally substituted aromatic ring; Xa, Xc, Ya, Yc, Z1 and Z2 are each a bond, O, S, —CO—, —CS—, —CR3(OR4)—, —NR5—, —SO—, —SO2—, —CONR6— or —NR6CO— (wherein R3, R4, R5 and R6 are as defined in the specification); Xb and Yb are each a bond or a divalent hydrocarbon group having 1 to 20 carbon atoms; R1 is an optionally substituted hydrocarbon group; ring A is an optionally further substituted aromatic ring, provided that the ring should not be benzimidazole; n is an integer of 1 to 8; ring B is an optionally further substituted aromatic ring, provided that the ring should not be oxazole; W is a divalent saturated hydrocarbon group having 1 to 20 carbon atoms; and R2 is —OR8 or —NR9R10 (wherein R8, R9 and R10 are as defined in the specification) or a salt thereof, is useful as an agent for the prophylaxis or treatment of diabetes and the like.Type: ApplicationFiled: November 25, 2005Publication date: February 28, 2008Inventors: Tsuyoshi Maekawa, Osamu Ujikawa, Hidenori Abe, Izumi Nomura
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Patent number: 6898840Abstract: A method of fabricating a magnetic head device comprising a slider having a magnetic head element, a suspension structure made of a thin resilient material and having one end supporting the slider and the other end to be attached to another member, and a head IC chip. The head IC chip is mounted on the suspension structure so as to face a magnetic recording disc and at a position spaced from the slider-supporting one end of the suspension structure by an intervening portion of the suspension structure. The position is selected so that the intervening portion is effective to suppress a temperature increase in the head IC chip due to at least thermal conduction through the intervening portion.Type: GrantFiled: February 17, 2000Date of Patent: May 31, 2005Assignee: TDK CorporationInventors: Masashi Shiraishi, Izumi Nomura, Tsutomu Aoyama, Isamu Sato, Masanori Sakai, Tsuyoshi Umehara, Kenichi Takano, Haruyuki Morita
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Patent number: 6522502Abstract: There is disclosed a magnetic disc device wherein temperature increase in the head IC chip can effectively suppressed. The magnetic head device comprises a slider having a magnetic head, a suspension structure having one end supporting the slider, and a head IC chip, the head IC chip being mounted on the suspension structure at a side adapted to be faced to a magnetic recording disc. A flow of air produced by the rotation of the magnetic disc cols the head IC chip in operation.Type: GrantFiled: April 6, 2000Date of Patent: February 18, 2003Assignee: TDK CorporationInventors: Masashi Shiraishi, Izumi Nomura, Tsutomu Aoyama, Isamu Sato, Masanori Sakai, Tsuyoshi Umehara, Kenichi Takano, Haruyuki Morita