Patents by Inventor Izumi Nomura

Izumi Nomura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10017508
    Abstract: The present invention provides a compound having a PDE2A selective inhibitory action, which is useful as an agent for the prophylaxis or treatment of schizophrenia, Alzheimer's disease and the like. The present invention is a compound represented by the formula (1): wherein each symbol is as described in the specification, or a salt thereof.
    Type: Grant
    Filed: September 13, 2016
    Date of Patent: July 10, 2018
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Satoshi Mikami, Shinji Nakamura, Tomoko Ashizawa, Shigekazu Sasaki, Takahiko Taniguchi, Izumi Nomura, Masanori Kawasaki
  • Publication number: 20170129887
    Abstract: The present invention provides a compound having a PDE2A selective inhibitory action, which is useful as an agent for the prophylaxis or treatment of schizophrenia, Alzheimer's disease and the like. The present invention is a compound represented by the formula (1): wherein each symbol is as described in the specification, or a salt thereof.
    Type: Application
    Filed: September 13, 2016
    Publication date: May 11, 2017
    Inventors: Satoshi MIKAMI, Shinji NAKAMURA, Tomoko ASHIZAWA, Shigekazu SASAKI, Takahiko TANIGUCHI, Izumi NOMURA, Masanori KAWASAKI
  • Patent number: 9624184
    Abstract: The present invention relates to a compound represented by the formula (I), which is useful as an agent for the prophylaxis or treatment of epilepsy, neurodegenerative disease and the like. In the formula (I), each symbol is as defined in the specification.
    Type: Grant
    Filed: April 3, 2014
    Date of Patent: April 18, 2017
    Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Tatsuki Koike, Masato Yoshikawa, Izumi Nomura, Yoshiteru Ito, Eiji Kimura, Haruhi Ando, Tomoaki Hasui, Toshiya Nishi
  • Patent number: 9527841
    Abstract: The present invention provides a compound having a PDE2A selective inhibitory action, which is useful as an agent for the prophylaxis or treatment of schizophrenia, Alzheimer's disease and the like. The present invention is a compound represented by the formula (1): wherein each symbol is as described in the specification, or a salt thereof.
    Type: Grant
    Filed: July 12, 2013
    Date of Patent: December 27, 2016
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Shinji Nakamura, Satoshi Mikami, Kawasaki Masanori, Izumi Nomura, Tomoko Ashizawa, Takahiko Taniguchi
  • Patent number: 9469637
    Abstract: The present invention provides a compound having a PDE2A selective inhibitory action, which is useful as an agent for the prophylaxis or treatment of schizophrenia, Alzheimer's disease and the like. The present invention is a compound represented by the formula (1): wherein each symbol is as described in the specification, or a salt thereof.
    Type: Grant
    Filed: April 24, 2013
    Date of Patent: October 18, 2016
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Satoshi Mikami, Shinji Nakamura, Tomoko Ashizawa, Shigekazu Sasaki, Takahiko Taniguchi, Izumi Nomura, Masanori Kawasaki
  • Publication number: 20160264536
    Abstract: The problem of the present invention is to provide a compound having a PDE2A inhibitory action, and useful as a prophylactic or therapeutic drug for schizophrenia, Alzheimer's disease and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof.
    Type: Application
    Filed: October 22, 2014
    Publication date: September 15, 2016
    Inventors: Masaki SETO, Yoshihiro BANNO, Toshihiro IMAEDA, Yuichi KAJITA, Tomoko ASHIZAWA, Masanori KAWASAKI, Shinji NAKAMURA, Satoshi MIKAMI, Izumi NOMURA, Takahiko TANIGUCHI, Shogo MARUI
  • Publication number: 20160159808
    Abstract: A compound represented by the formula (I): wherein each symbol is as described in the SPECIFICATION, or a salt thereof has a PDE2A inhibitory action, and is useful as a prophylactic or therapeutic drug for schizophrenia, Alzheimer's disease and the like.
    Type: Application
    Filed: July 23, 2014
    Publication date: June 9, 2016
    Inventors: Masanori Kawasaki, Satoshi Mikami, Shinji Nakamura, Nobuyuki Negoro, Shuhei Ikeda, Izumi Nomura, Tomoko Ashizawa, Toshihiro Imaeda, Masaki Seto, Shigekazu Sasaki, Shogo Marui, Takahiko Taniguchi
  • Patent number: 9296746
    Abstract: The present invention provides a compound or a salt thereof useful for an agent for the prophylaxis or treatment of neurodegenerative disease and the like. The present invention relates to a compound represented by the formula wherein each symbol is as defined in the present specification, or a salt thereof.
    Type: Grant
    Filed: October 15, 2013
    Date of Patent: March 29, 2016
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Tatsuki Koike, Masato Yoshikawa, Izumi Nomura, Yoshiteru Ito, Eiji Kimura, Tomoaki Hasui, Haruhi Ando, Hiromi Fukuda
  • Publication number: 20160052897
    Abstract: The present invention relates to a compound represented by the formula (I), which is useful as an agent for the prophylaxis or treatment of epilepsy, neurodegenerative disease and the like. In the formula (I), each symbol is as defined in the specification.
    Type: Application
    Filed: April 3, 2014
    Publication date: February 25, 2016
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Tatsuki KOIKE, Masato YOSHIKAWA, Izumi NOMURA, Yoshiteru ITO, Eiji KIMURA, Haruhi ANDO, Tomoaki HASUI, Toshiya NISHI
  • Publication number: 20150266872
    Abstract: The present invention provides a compound or a salt thereof useful for an agent for the prophylaxis or treatment of neurodegenerative disease and the like. The present invention relates to a compound represented by the formula wherein each symbol is as defined in the present specification, or a salt thereof.
    Type: Application
    Filed: October 15, 2013
    Publication date: September 24, 2015
    Inventors: Tatsuki Koike, Masato Yoshikawa, Izumi Nomura, Yoshiteru Ito, Eiji Kimura, Tomoaki Hasui, Haruhi Ando, Hiromi Fukuda, Toshiya Nishi
  • Publication number: 20150158863
    Abstract: The present invention provides a compound having a PDE2A selective inhibitory action, which is useful as an agent for the prophylaxis or treatment of schizophrenia, Alzheimer's disease and the like. The present invention is a compound represented by the formula (1): wherein each symbol is as described in the specification, or a salt thereof.
    Type: Application
    Filed: July 12, 2013
    Publication date: June 11, 2015
    Applicant: Takeda Pharmaceutical Company Limited
    Inventors: Shinji Nakamura, Satoshi Mikami, Kawasaki Masanori, Izumi Nomura, Tomoko Ashizawa, Takahiko Taniguchi
  • Publication number: 20150105373
    Abstract: The present invention provides a compound having a PDE2A selective inhibitory action, which is useful as an agent for the prophylaxis or treatment of schizophrenia, Alzheimer's disease and the like. The present invention is a compound represented by the formula (1): wherein each symbol is as described in the specification, or a salt thereof.
    Type: Application
    Filed: April 24, 2013
    Publication date: April 16, 2015
    Inventors: Satoshi Mikami, Shinji Nakamura, Tomoko Ashizawa, Shigekazu Sasaki, Takahiko Taniguchi, Izumi Nomura, Masanori Kawasaki
  • Patent number: 8916549
    Abstract: Provision of a compound having a serotonin 5-HT2C receptor activating action. A compound represented by the formula (I): wherein each symbol is as described in the description, or a salt thereof.
    Type: Grant
    Filed: August 3, 2010
    Date of Patent: December 23, 2014
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Takahiro Matsumoto, Izumi Nomura
  • Publication number: 20120196848
    Abstract: Provision of a compound having a serotonin 5-HT2C receptor activating action. A compound represented by the formula (I): wherein each symbol is as described in the description, or a salt thereof.
    Type: Application
    Filed: August 3, 2010
    Publication date: August 2, 2012
    Inventors: Takahiro Matsumoto, Izumi Nomura
  • Publication number: 20120135979
    Abstract: Provided is a compound having a serotonin 5-HT2C receptor activating action, useful for lower urinary tract conditions, obesity and cancer. A compound represented by the formula (I0): wherein each symbol is as defined in the specification, or a salt thereof.
    Type: Application
    Filed: June 14, 2010
    Publication date: May 31, 2012
    Inventors: Shigekazu Sasaki, Tomokazu Kusumoto, Izumi Nomura, Hironobu Maezaki
  • Publication number: 20100317651
    Abstract: Provided is a compound having a serotonin 5-HT2C receptor activating action. A compound represented by the formula (I0): wherein each symbol is as defined in the specification, or a salt thereof.
    Type: Application
    Filed: June 14, 2010
    Publication date: December 16, 2010
    Inventors: Shigekazu Sasaki, Tomokazu Kusumoto, Izumi Nomura, Hironobu Maezaki
  • Publication number: 20090318412
    Abstract: The present invention provides a tricyclic heterocyclic compound having a serotonin 5-HT2C receptor activation action and the like. A 5-HT2C receptor activator containing a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof or a prodrug thereof.
    Type: Application
    Filed: July 10, 2007
    Publication date: December 24, 2009
    Inventors: Takahiro Matsumoto, Izumi Kamo, Izumi Nomura
  • Publication number: 20080051418
    Abstract: A compound represented by the formula (I): wherein Ar is an optionally substituted aromatic ring; Xa, Xc, Ya, Yc, Z1 and Z2 are each a bond, O, S, —CO—, —CS—, —CR3(OR4)—, —NR5—, —SO—, —SO2—, —CONR6— or —NR6CO— (wherein R3, R4, R5 and R6 are as defined in the specification); Xb and Yb are each a bond or a divalent hydrocarbon group having 1 to 20 carbon atoms; R1 is an optionally substituted hydrocarbon group; ring A is an optionally further substituted aromatic ring, provided that the ring should not be benzimidazole; n is an integer of 1 to 8; ring B is an optionally further substituted aromatic ring, provided that the ring should not be oxazole; W is a divalent saturated hydrocarbon group having 1 to 20 carbon atoms; and R2 is —OR8 or —NR9R10 (wherein R8, R9 and R10 are as defined in the specification) or a salt thereof, is useful as an agent for the prophylaxis or treatment of diabetes and the like.
    Type: Application
    Filed: November 25, 2005
    Publication date: February 28, 2008
    Inventors: Tsuyoshi Maekawa, Osamu Ujikawa, Hidenori Abe, Izumi Nomura
  • Patent number: 6898840
    Abstract: A method of fabricating a magnetic head device comprising a slider having a magnetic head element, a suspension structure made of a thin resilient material and having one end supporting the slider and the other end to be attached to another member, and a head IC chip. The head IC chip is mounted on the suspension structure so as to face a magnetic recording disc and at a position spaced from the slider-supporting one end of the suspension structure by an intervening portion of the suspension structure. The position is selected so that the intervening portion is effective to suppress a temperature increase in the head IC chip due to at least thermal conduction through the intervening portion.
    Type: Grant
    Filed: February 17, 2000
    Date of Patent: May 31, 2005
    Assignee: TDK Corporation
    Inventors: Masashi Shiraishi, Izumi Nomura, Tsutomu Aoyama, Isamu Sato, Masanori Sakai, Tsuyoshi Umehara, Kenichi Takano, Haruyuki Morita
  • Patent number: 6522502
    Abstract: There is disclosed a magnetic disc device wherein temperature increase in the head IC chip can effectively suppressed. The magnetic head device comprises a slider having a magnetic head, a suspension structure having one end supporting the slider, and a head IC chip, the head IC chip being mounted on the suspension structure at a side adapted to be faced to a magnetic recording disc. A flow of air produced by the rotation of the magnetic disc cols the head IC chip in operation.
    Type: Grant
    Filed: April 6, 2000
    Date of Patent: February 18, 2003
    Assignee: TDK Corporation
    Inventors: Masashi Shiraishi, Izumi Nomura, Tsutomu Aoyama, Isamu Sato, Masanori Sakai, Tsuyoshi Umehara, Kenichi Takano, Haruyuki Morita