Patents by Inventor J. Francis BORGIO

J. Francis BORGIO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENETIC TEST KIT FOR DETECTING THALASSEMIA
    Publication number: 20240132962
    Abstract: One aspect of the invention is a method for amplifying alpha globin genes HBA1, HBA2 and HBA12 in a single PCR tube to determine an HBA genotype of a subject. This method employs five primers selected to accurate and sensitively identify the HBA1, HBA2, and HBA12, a gene found at a higher frequency in citizens of Saudi Arabia, by accurately annealing to nucleic acids in a biological sample and simultaneously amplifying sequences encoding the alpha globin genes. This invention includes a procedure and required reagents for the amplification of alpha globin genes in a single PCR tube.
    Type: Application
    Filed: January 2, 2024
    Publication date: April 25, 2024
    Applicant: Imam Abdulrahman Bin Faisal University
    Inventors: J. Francis BORGIO, Sayed ABDULAZEEZ, Fahd A. AL-MUHANNA, Amein Kadhem AL-ALI
  • METHOD FOR EARLY DETERMINATION OF GENDER BY MULTIPLEX PCR DETECTING FOUR GENES
    Publication number: 20240052417
    Abstract: A non-invasive method for determining fetal gender prior to the second trimester using multiplex polymerase chain reaction to identify target segments of the SRY, DAZ2 and TSPY1 genes which are located on the Y chromosome of a male fetus. A kit for determining gender comprising primers that amplify target segments of the SRY, DAZ2 and TSPY1 genes.
    Type: Application
    Filed: August 12, 2022
    Publication date: February 15, 2024
    Applicants: Imam Abdulrahman Bin Faisal University, King Saud University
    Inventors: J. Francis BORGIO, Norah Fahad ALHUR, Nourah H. AL QAHTANI, Sayed ABDULAZEEZ, Noor B. ALMANDIL, Entissar Asulaiman ALSUHAIBANI
  • Primer compositions for detecting thalassemia
    Patent number: 11884981
    Abstract: One aspect of the invention is a method for amplifying alpha globin genes HBA1, HBA2 and HBA12 in a single PCR tube to determine an HBA genotype of a subject. This method employs five primers selected to accurate and sensitively identify the HBA1, HBA2, and HBA12, a gene found at a higher frequency in citizens of Saudi Arabia, by accurately annealing to nucleic acids in a biological sample and simultaneously amplifying sequences encoding the alpha globin genes. This invention includes a procedure and required reagents for the amplification of alpha globin genes in a single PCR tube.
    Type: Grant
    Filed: May 27, 2021
    Date of Patent: January 30, 2024
    Assignee: Imam Abdulrahman Bin Faisal University
    Inventors: J. Francis Borgio, Sayed Abdulazeez, Fahd A. Al-Muhanna, Amein Kadhem Al-Ali
  • PRIMER COMPOSITIONS FOR DETECTING THALASSEMIA
    Publication number: 20210285051
    Abstract: One aspect of the invention is a method for amplifying alpha globin genes HBA1, HBA2 and HBA12 in a single PCR tube to determine an HBA genotype of a subject. This method employs five primers selected to accurate and sensitively identify the HBA1, HBA2, and HBA12, a gene found at a higher frequency in citizens of Saudi Arabia, by accurately annealing to nucleic acids in a biological sample and simultaneously amplifying sequences encoding the alpha globin genes. This invention includes a procedure and required reagents for the amplification of alpha globin genes in a single PCR tube.
    Type: Application
    Filed: May 27, 2021
    Publication date: September 16, 2021
    Applicant: King Faisal Street, Eastern Province
    Inventors: J. Francis BORGIO, Sayed ABDULAZEEZ, Fahd A. AL-MU HANNA, Amein Kadhem AL-ALI
  • Single tube multiplex PCR method for the detection of HBA1, HBA2 and HBA12 genes
    Patent number: 11118229
    Abstract: One aspect of the invention is a method for amplifying alpha globin genes HBA1, HBA2 and HBA12 in a single PCR tube to determine an HBA genotype of a subject. This method employs five primers selected to accurate and sensitively identify the HBA1, HBA2, and HBA12, a gene found at a higher frequency in citizens of Saudi Arabia, by accurately annealing to nucleic acids in a biological sample and simultaneously amplifying sequences encoding the alpha globin genes. This invention includes a procedure and required reagents for the amplification of alpha globin genes in a single PCR tube.
    Type: Grant
    Filed: January 25, 2019
    Date of Patent: September 14, 2021
    Assignee: Imam Abdulrahman Bin Faisal University
    Inventors: J. Francis Borgio, Sayed Abdulazeez, Fahd A. Al-Muhanna, Amein Kadhem Al-Ali
  • SINGLE TUBE MULTIPLEX PCR METHOD FOR THE DETECTION OF HBA1, HBA2 AND HBA12 GENES
    Publication number: 20200239956
    Abstract: One aspect of the invention is a method for amplifying alpha globin genes HBA1, HBA2 and HBA12 in a single PCR tube to determine an HBA genotype of a subject. This method employs five primers selected to accurate and sensitively identify the HBA1, HBA2, and HBA12, a gene found at a higher frequency in citizens of Saudi Arabia, by accurately annealing to nucleic acids in a biological sample and simultaneously amplifying sequences encoding the alpha globin genes. This invention includes a procedure and required reagents for the amplification of alpha globin genes in a single PCR tube.
    Type: Application
    Filed: January 25, 2019
    Publication date: July 30, 2020
    Applicant: Imam Abdulrahman Bin Faisal University
    Inventors: J. Francis BORGIO, Sayed ABDULAZEEZ, Fahd A. AL-MUHANNA, Amein Kadhem AL-ALI