Patents by Inventor J. Frank Butler

J. Frank Butler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF
    Publication number: 20240117347
    Abstract: Among other things, the present disclosure relates to designed oligonucleotides, compositions, and methods thereof. In some embodiments, provided oligonucleotide compositions provide altered splicing of a transcript. In some embodiments, provided oligonucleotide compositions have low toxicity. In some embodiments, provided oligonucleotide compositions provide improved protein binding profiles. In some embodiments, provided oligonucleotide compositions have improved delivery. In some embodiments, provided oligonucleotide compositions have improved uptake. In some embodiments, the present disclosure provides methods for treatment of diseases using provided oligonucleotide compositions.
    Type: Application
    Filed: December 6, 2022
    Publication date: April 11, 2024
    Inventors: David Charles Donnell Butler, Sethumadhavan Divakaramenon, Christopher J. Francis, Maria David Frank-Kamenetsky, Naoki Iwamoto, Genliang Lu, Subramanian Marappan, Meena, Chandra Vargeese, Gregory L. Verdine, Hailin Yang, Jason Jingxin Zhang
  • Scaffold
    Patent number: 5579865
    Abstract: A modular scaffolding assembly in which the platform may move up or down in a continuous motion. A platform carriage is engaged with a tower by spring loaded friction blocks and climbs or descends the tower along a pair of stepped racks. Platform modules may be removably connected to the platform carriage.
    Type: Grant
    Filed: February 23, 1994
    Date of Patent: December 3, 1996
    Inventors: J. Frank Butler, Robert J. Leach