Patents by Inventor J. Matthew Barnes

J. Matthew Barnes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of purifying tumor cells using shear stress
    Patent number: 11921020
    Abstract: Methods for isolating viable cancer cells from a sample that comprises a mixture of cancerous cells and normal (non-cancerous) cells are provided. In the methods, a fluid preparation comprising a mixture of cancerous and normal cells is repeatedly exposed to fluid shear stresses, whereby the repeated exposure to the fluid shear stresses preferentially imparts fluid shear stress-resistance to the cancerous cells.
    Type: Grant
    Filed: July 27, 2020
    Date of Patent: March 5, 2024
    Assignee: UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Michael D. Henry, J. Matthew Barnes
  • METHOD OF PURIFYING TUMOR CELLS USING SHEAR STRESS
    Publication number: 20210048379
    Abstract: Methods for isolating viable cancer cells from a sample that comprises a mixture of cancerous cells and normal (non-cancerous) cells are provided. In the methods, a fluid preparation comprising a mixture of cancerous and normal cells is repeatedly exposed to fluid shear stresses, whereby the repeated exposure to the fluid shear stresses preferentially imparts fluid shear stress-resistance to the cancerous cells.
    Type: Application
    Filed: July 27, 2020
    Publication date: February 18, 2021
    Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Michael D. Henry, J. Matthew Barnes
  • Method of purifying tumor cells using shear stress
    Patent number: 10768080
    Abstract: Methods for isolating viable cancer cells from a sample that comprises a mixture of cancerous cells and normal (non-cancerous) cells are provided. In the methods, a fluid preparation comprising a mixture of cancerous and normal cells is repeatedly exposed to fluid shear stresses, whereby the repeated exposure to the fluid shear stresses preferentially imparts fluid shear stress-resistance to the cancerous cells.
    Type: Grant
    Filed: April 2, 2018
    Date of Patent: September 8, 2020
    Assignee: University of Iowa Research Foundation
    Inventors: Michael D. Henry, J. Matthew Barnes
  • METHOD OF PURIFYING TUMOR CELLS USING SHEAR STRESS
    Publication number: 20180224359
    Abstract: Methods for isolating viable cancer cells from a sample that comprises a mixture of cancerous cells and normal (non-cancerous) cells are provided. In the methods, a fluid preparation comprising a mixture of cancerous and normal cells is repeatedly exposed to fluid shear stresses, whereby the repeated exposure to the fluid shear stresses preferentially imparts fluid shear stress-resistance to the cancerous cells.
    Type: Application
    Filed: April 2, 2018
    Publication date: August 9, 2018
    Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Michael D. Henry, J. Matthew Barnes
  • Isolation and characterization of tumor cells using shear stress measurements
    Patent number: 9435721
    Abstract: Methods for isolating viable cancer cells from a sample that comprises a mixture of cancerous cells and normal (non-cancerous) cells are provided. In the methods, a fluid preparation comprising a mixture of cancerous and normal cells is repeatedly exposed to fluid shear stresses, whereby the repeated exposure to the fluid shear stresses preferentially imparts fluid shear stress-resistance to the cancerous cells.
    Type: Grant
    Filed: May 15, 2015
    Date of Patent: September 6, 2016
    Assignee: University of Iowa Research Foundation
    Inventors: Michael D. Henry, J. Matthew Barnes
  • ISOLATION AND CHARACTERIZATION OF TUMOR CELLS USING SHEAR STRESS MEASUREMENTS
    Publication number: 20150316456
    Abstract: Methods for isolating viable cancer cells from a sample that comprises a mixture of cancerous cells and normal (non-cancerous) cells are provided. In the methods, a fluid preparation comprising a mixture of cancerous and normal cells is repeatedly exposed to fluid shear stresses, whereby the repeated exposure to the fluid shear stresses preferentially imparts fluid shear stress-resistance to the cancerous cells.
    Type: Application
    Filed: May 15, 2015
    Publication date: November 5, 2015
    Inventors: Michael D. Henry, J. Matthew Barnes
  • ISOLATION AND CHARACTERIZATION OF TUMOR CELLS USING SHEAR STRESS MEASUREMENTS
    Publication number: 20150307848
    Abstract: Methods for isolating viable cancer cells from a sample that comprises a mixture of cancerous cells and normal (non-cancerous) cells are provided. In the methods, a fluid preparation comprising a mixture of cancerous and normal cells is repeatedly exposed to fluid shear stresses, whereby the repeated exposure to the fluid shear stresses preferentially imparts fluid shear stress-resistance to the cancerous cells.
    Type: Application
    Filed: May 15, 2015
    Publication date: October 29, 2015
    Inventors: Michael D. Henry, J. Matthew Barnes
  • Isolation and characterization of tumor cells using shear stress measurements
    Patent number: 9063118
    Abstract: Methods for isolating viable cancer cells from a sample that comprises a mixture of cancerous cells and normal (non-cancerous) cells are provided. In the methods, a fluid preparation comprising a mixture of cancerous and normal cells is repeatedly exposed to fluid shear stresses, whereby the repeated exposure to the fluid shear stresses preferentially imparts fluid shear stress-resistance to the cancerous cells.
    Type: Grant
    Filed: March 22, 2012
    Date of Patent: June 23, 2015
    Assignee: University of Iowa Research Foundation
    Inventors: Michael D. Henry, J. Matthew Barnes
  • ISOLATION AND CHARACTERIZATION OF TUMOR CELLS USING SHEAR STRESS MEASUREMENTS
    Publication number: 20140038231
    Abstract: Methods for isolating viable cancer cells from a sample that comprises a mixture of cancerous cells and normal (non-cancerous) cells are provided. In the methods, a fluid preparation comprising a mixture of cancerous and normal cells is repeatedly exposed to fluid shear stresses, whereby the repeated exposure to the fluid shear stresses preferentially imparts fluid shear stress-resistance to the cancerous cells.
    Type: Application
    Filed: March 22, 2012
    Publication date: February 6, 2014
    Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Michael D. Henry, J. Matthew Barnes