Abstract: An improved PCB Rogowski coil addresses the challenges presented by space constraints within circuit interrupters. The disclosed coil comprises a plurality of PCBs that are coupled together, in contrast with known coils constructed from only a single PCB. During a pre-assembly stage, three PCBs are coupled to one another in order to form a partial coil assembly structured to be mounted onto a circuit interrupter primary conductor. After the partial coil assembly is mounted onto the primary conductor, a fourth PCB is connected to the partial coil assembly via press-fit connectors to form a complete coil. In contrast with known PCB Rogowski coils which are structured to be mounted perpendicularly to the primary conductor, the disclosed modular PCB Rogowski coil enables a substantial portion of the PCB surface area to be mounted in parallel to the primary conductor and to thus occupy significantly less space than known PCB Rogowski coils.

Abstract: The present disclosure provides one or more amino lipids such as an amino lipids containing a sulfonic acid or sulfonic acid derivative of the formulas: wherein the variables are as defined herein. These amino lipids may be used in compositions with one or more helper lipids and a nucleic acid therapeutic agent. These compositions may be used to treat a disease or disorder such as cancer, cystic fibrosis, or other genetic diseases.

Abstract: An apparatus attaches to a microscope slide to form an enclosed fluidic chamber with input and output ports, where a tissue or cell sample on the slide can be processed using techniques such as immunohistochemical staining. Flow of reagents within the chamber can be laminar and highly uniform across the sample surface to achieve staining that is free of gradients. The sample can be imaged prior to, during, or after any given processing step. Methods for staining and imaging a sample can be implemented through one or more rounds of labeling, label removal or erasure and imaging. Samples can be imaged many times to achieve very high multiplexing levels. Samples can be placed on an imaging apparatus at various times and removed from the imaging apparatus for certain steps.

Abstract: A refrigerator includes a wrapper having an opening with a front edge. A liner includes an opening and a front edge. A thermal bridge interconnects the wrapper and the liner to form a vacuum insulated cavity therebetween. The thermal bridge includes an outwardly opening channel and first and second inwardly opening channels. The front edge of wrapper is received in the first inwardly opening channel, and the front edge of the liner is received in the second inwardly opening channel. The second inwardly opening channel is inset relative to the first inwardly opening channel on the thermal bridge. A conduit is disposed within the outwardly opening channel and is configured to circulate a heated medium. The wrapper and liner are contemplated to be comprised of conductive materials, such sheet metal, while the thermal bridge is comprised of a thermally resistant material, such as a polymeric material.

Abstract: A method of operating an insulin infusion device involves: operating the infusion device in an automatic mode to automatically control delivery of insulin to a user, in accordance with a first target glucose setpoint value; receiving user status data that indicates sleeping status of the user, the user status data generated by a sleep detection system; and determining, from the user status data, that the user is sleeping while the insulin infusion device is operating in the automatic mode. In response to the determining, the method transitions from the first target glucose setpoint value to a second (different) target glucose setpoint value for use during the automatic mode, the transitioning occurring without user input. The method continues to operate the infusion device in the automatic mode to automatically control delivery of insulin to the user, in accordance with the second target glucose setpoint value.

Abstract: Self-cleaning features for extraction cleaners and attachments for extraction cleaners, such as accessory tools, wands, and/or hoses, are provided. The self-cleaning features are configured redirect cleaning fluid from a fluid supply system of the extraction cleaner into a working air or fluid recovery path of the extraction cleaner, including, but not limited to into the working air or fluid recovery path of a tool, wand, and/or hose of the extraction cleaner.

Abstract: Various embodiments are directed to a method of driving an end effector coupled to an ultrasonic drive system of a surgical instrument. The method comprises generating at least one electrical signal. The at least one electrical signal is monitored against a first set of logic conditions. A first response is triggered when the first set of logic conditions is met. A parameter is determined from the at least one electrical signal.

Abstract: This disclosure relates to methods and agents for modulating adoptive immunotherapy to enable bioengineered immune cells to utilize xenobiotic fuel, e.g., in a low glucose environment. The immune cells may be used, e.g., for treatment of a tumor or cancer, such as part of a therapeutic treatment of cancer or for treatment of a bacterial, fungal, or viral infection, alone or in combination with a low glucose (e.g., ketogenic) diet. They may also be used to treat a tumor, a cancer, an infection, an autoimmune disease, or an inflammatory or neuroinflammatory disease or condition in a patient on a low glucose diet. The immune cells may be used in combination with a scaffold or platform or with a microparticle or nanoparticle for localization of treatment or xenobiotic nutrients or for controlled release, as well as for other therapeutic uses.

Abstract: A computer-implemented method for tracking surgical textiles includes receiving a first image comprising a first textile-depicting image region, receiving a second image comprising a second textile-depicting image region, measuring a likelihood that the first and second image regions depict at least a portion of the same textile, and incrementing an index counter if the measure of likelihood does not meet a predetermined threshold. The measure of likelihood may be based on at least one classification feature at least partially based on aspects or other features of the first and second images.

Abstract: A method for making electrophoretic displays layers including various thin films that are deposited directly onto a layer of microcapsules of electrophoretic media. In an embodiment, a thin film of a light-transmissive conductive material is deposited to create a clear front electrode for an electrophoretic display. In some embodiments, both a dielectric layer and a thin film of a light-transmissive conductive material will be deposited onto the microcapsules.

Abstract: Flow modifiers are positioned at one or more discrete points along the underside of a boat hull to generate secondary wakes that interfere with the primary wake generated by the boat hull and result in a desired modified wake useful for various watersports. The flow modifiers are formed integrally with the boat hull or affixed thereto, and can be selectively extendable and retractable relative thereto.

Abstract: Systems and methods for displaying estimated relevance indicators for result sets of documents and for displaying query visualizations are disclosed. A method includes receiving a search query including a plurality of query terms. The method further includes searching a database using the search query to identify the result set of documents and calculating an estimated relevance score for the result set of documents. The estimated relevance score is indicative of a degree to which the result set of documents are relevant to the search query. The method further includes providing for display the estimated relevance indicator based on the estimated relevance score. The estimated relevance indicator provides a visual indication of the degree to which the result set of documents are relevant to the search query. Query visualizations including a plurality of nodes and a plurality of connectors are also disclosed.

Abstract: A fuel element has a ratio of area of fissionable nuclear fuel in a cross-section of the tubular fuel element perpendicular to the longitudinal axis to total area of the interior volume in the cross-section of the tubular fuel element that varies with position along the longitudinal axis. The ratio can vary with position along the longitudinal axis between a minimum of 0.30 and a maximum of 1.0. Increasing the ratio above and below the peak burn-up location associated with conventional systems reduces the peak burn-up and flattens and shifts the burn-up distribution, which is preferably Gaussian. The longitudinal variation can be implemented in fuel assemblies using fuel bodies, such as pellets, rods or annuli, or fuel in the form of metal sponge and meaningfully increases efficiency of fuel utilization.

Abstract: Pyrrolidine main protease inhibitors are described that are effective as antiviral compounds.

Abstract: Techniques described herein include providing payment and access infrastructure for an array of transportation services, such as a set of transit or mobility services that might be provided by one or more governments, public agencies, and/or other public entities. In one example, this disclosure describes a method that includes enabling, by a computing system, a user to register for mobility benefits using a verification system, wherein the mobility benefits are provided by a provider entity; receiving, by the computing system and from the verification system, information about the user; establishing, by the computing system, an account linked to the provider entity; detecting, by the computing system, a request to access mobility benefits; allocating, by the computing system, funds from the account to pay for the mobility benefits.

Abstract: Techniques are described for providing managed virtual computer networks that have a configured logical network topology with virtual networking devices, such as by a network-accessible configurable network service, with corresponding networking functionality provided for communications between multiple computing nodes of the virtual computer network by emulating functionality that would be provided by the virtual networking devices if they were physically present.

Abstract: In general, the invention relates to pharmaceutical compositions comprising (R)-oxybutynin and a norepinephrine reuptake inhibitor (NRI) and methods of treating Sleep Apnea comprising administering (R)-oxybutynin and a norepinephrine reuptake inhibitor (NRI). In some embodiments, the NRI is atomoxetine.

Abstract: A method of using an occlusion clamp, the method comprising: (a) repositioning a tongs so that tissue interposes the tongs, the tongs comprising a first longitudinal segment operatively coupled proximally to a second longitudinal segment, the tongs including a first spring exerting a proximal bias tending to direct a proximal portion of each of the first and second longitudinal segments toward one another, where each of the first and second longitudinal segments includes a distal free end; (b) repositioning a second spring distally along each of the first and second longitudinal segments to exert a bias tending to direct a distal portion of each of the first and second longitudinal segments toward one another, where repositioning of the tongs so that tissue interposes the tongs precedes repositioning the second spring distally along each of the first and second longitudinal segments.