Patents by Inventor Jérôme Bailly

Jérôme Bailly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10286008
    Abstract: A method for obtaining a stabilized suspension of red blood cells encapsulating an active ingredient, from resealed RBCs incorporating the active ingredient, the method comprising the incubation of the resealed RBCs in an incubation solution at an osmolality of no less than 280 m Osmol/kg, for a time of 30 minutes or more, the incubation solution being a solution that does not contain an agent which is denaturating for the RBC membrane, the liquid medium is then removed from the incubated suspension and the RBCs obtained are placed in suspension in a solution allowing the injection of the suspension in a patient. The suspensions obtained are particularly characterized by an extracellular haemoglobin level maintained at 0.5 or lower, in particular 0.2 g/dl or lower and/or a hemolysis rate maintained at 2 or less, in particular 1% or less, at 72 h after placing in suspension in a preservation solution and at a temperature of between 2 and 8° C.
    Type: Grant
    Filed: May 7, 2014
    Date of Patent: May 14, 2019
    Assignee: ERYTECH PHARMA
    Inventors: Yann Godfrin, Vanessa Bourgeaux, Jérôme Bailly
  • Publication number: 20160095884
    Abstract: A method for obtaining a stabilised suspension of red blood cells encapsulating an active ingredient, from resealed RBCs incorporating the active ingredient, the method comprising the incubation of the resealed RBCs in an incubation solution at an osmolality of no less than 280 m Osmol/kg, for a time of 30 minutes or more, the incubation solution being a solution that does not contain an agent which is denaturating for the RBC membrane, the liquid medium is then removed from the incubated suspension and the RBCs obtained are placed in suspension in a solution allowing the injection of the suspension in a patient. The suspensions obtained are particularly characterized by an extracellular haemoglobin level maintained at 0.5 or lower, in particular 0.2 g/dl or lower and/or a haemolysis rate maintained at 2 or less, in particular 1% or less, at 72 h after placing in suspension in a preservation solution and at a temperature of between 2 and 8° C.
    Type: Application
    Filed: May 7, 2014
    Publication date: April 7, 2016
    Applicant: ERYTECH PHARMA
    Inventors: Yann GODFRIN, Vanessa BOURGEAUX, Jérôme BAILLY
  • Patent number: 9092980
    Abstract: According to the invention, a terrain avoidance maneuver is engaged when the alerts of a given pair of alerts are emitted simultaneously, the triggering of one of the alerts depending on the information provided by a first measurement chain and the triggering of the other alert of the pair relying on information provided by a second measurement chain, distinct from and independent of the first chain.
    Type: Grant
    Filed: November 12, 2009
    Date of Patent: July 28, 2015
    Assignee: AIRBUS OPERATIONS SAS
    Inventors: Paule Botargues, Nicolas Caule, Christelle Ledauphin, Jérôme Bailly, Isabelle Lacaze, Sylvain Thezelais, Jérôme Goyet
  • Patent number: 8200421
    Abstract: An altitude profile representative of the terrain overflown by an aircraft is established. Thereafter, an altitude limit curve which comprises an intersection with the altitude profile upon the engagement of a terrain avoidance maneuver is determined. As soon as there is no longer any intersection of the limit curve with the altitude profile, the terrain avoidance maneuver is interrupted.
    Type: Grant
    Filed: October 20, 2009
    Date of Patent: June 12, 2012
    Assignee: Airbus Operations SAS
    Inventors: Paule Botargues, Nicolas Caule, Christelle Ledauphin, Jerome Bailly, Isabelle Lacaze, Sylvain Thezelais, Jerome Goyet
  • Patent number: 8108086
    Abstract: An aircraft guidance and piloting system automatically guides and pilots an aircraft in the event a pilot is unable to guide or pilot the aircraft. Upon determining the pilot's inability to control the aircraft, a processor transmits an automatic engagement command to a control unit. The control unit guides and pilots the aircraft to an alternative airport for landing.
    Type: Grant
    Filed: June 10, 2008
    Date of Patent: January 31, 2012
    Assignee: Airbus Operations SAS
    Inventors: Jerome Bailly, Isabelle Lacaze
  • Publication number: 20100125381
    Abstract: According to the invention, a terrain avoidance maneuver is engaged when the alerts of a given pair of alerts are emitted simultaneously, the triggering of one of the alerts depending on the information provided by a first measurement chain and the triggering of the other alert of the pair relying on information provided by a second measurement chain, distinct from and independent of the first chain.
    Type: Application
    Filed: November 12, 2009
    Publication date: May 20, 2010
    Applicant: AIRBUS OPERATIONS (SAS)
    Inventors: Paule Botargues, Nicolas Caule, Christelle Ledauphin, Jerome Bailly, Isabelle Lacaze, Sylvain Thezelais, Jerome Goyet
  • Publication number: 20100100261
    Abstract: According to the invention, an altitude profile (PA) representative of the terrain overflown by the aircraft (AC) is established, and then an altitude limit curve (C) which comprises an intersection with said profile (PA) upon the engagement of a terrain avoidance maneuver is determined. As soon as there is no longer any intersection of the limit curve (C) with the altitude profile (PA), said terrain avoidance maneuver is interrupted.
    Type: Application
    Filed: October 20, 2009
    Publication date: April 22, 2010
    Applicant: AIRBUS OPERATIONS
    Inventors: Paule Botargues, Nicolas Caule, Christelle Ledauphin, Jerome Bailly, Isabelle Lacaze, Sylvain Thezelais, Jerome Goyet
  • Publication number: 20090319104
    Abstract: The system (1) comprises means (3A to 3D) for detecting incapacity of the pilots to control the aircraft, and means (5) for automatically guiding and piloting the aircraft until it lands at an airport, on detection of such an incapacity.
    Type: Application
    Filed: June 10, 2008
    Publication date: December 24, 2009
    Applicant: AIRBUS France
    Inventors: Jerome Bailly, Isabelle Lacaze