Abstract: The present invention generally relates to novel bispecific antigen binding molecules for T cell activation and re-direction to specific target cells. In addition, the present invention relates to polynucleotides encoding such bispecific antigen binding molecules, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the bispecific antigen binding molecules of the invention, and to methods of using these bispecific antigen binding molecules in the treatment of disease.

Abstract: The present invention relates to a vehicle test bench for calibrating and/or testing systems of a vehicle which comprise at least one camera. The vehicle test bench has a target position for the vehicle. At least one surface that reproduces an image display and/or shows an image display is assigned to the cameras of systems to be tested. A plurality of elements that absorb stray light are provided, which elements each consist of a wall-like boundary of the vehicle test bench, which reduces penetration of light into the vehicle test bench. A plurality of wall-like boundaries results in lateral delimitation of the vehicle test bench on all sides.

Abstract: An apparatus for producing plastic containers is provided, comprising a heating device that heats plastic preforms, and including a shaping device provided downstream of this heating device in the transport direction of the plastic preforms, which shaping device shapes the plastic preforms into the plastic containers, wherein a tempering device for tempering the plastic preforms heated by the heating device is provided in the transport direction of the plastic preforms between the heating device and the shaping device, which tempering device has at least one tempering unit provided on a carrier rotatable about a predetermined rotary axis, and which tempering unit has at least two contacting devices, between which at least one section of the plastic preform can be received, which contacting devices can be moved in relation to one another along a predetermined direction.

Abstract: An apparatus for producing plastic containers is provided, comprising a heating device that heats plastic preforms, and including a shaping device provided downstream of this heating device in the transport direction of the plastic preforms, which shaping device shapes the plastic preforms into the plastic containers, wherein a tempering device for tempering the plastic preforms heated by the heating device is provided in the transport direction of the plastic preforms between the heating device and the shaping device, which tempering device has at least one tempering unit provided on a carrier rotatable about a predetermined rotary axis, and which tempering unit has at least two contacting devices, between which at least one section of the plastic preform can be received, which contacting devices can be moved in relation to one another along a predetermined direction.

Abstract: An apparatus is provided for producing plastic containers, comprising a heating device that heats plastic preforms, and including a shaping device provided downstream of this heating device in the transport direction of the plastic preforms, which shaping device shapes the plastic preforms into the plastic containers, wherein a tempering device for tempering the plastic preforms heated by the heating device is provided in the transport direction of the plastic preforms between the heating device and the shaping device, which tempering device has at least one tempering unit provided on a carrier rotatable about a predetermined rotary axis, and which tempering unit has at least two contacting devices, between which at least one section of the plastic preform can be received, which contacting devices can be moved in relation to one another along a predetermined direction.

Abstract: A cooking appliance component includes a cooking chamber for carrying out pyrolysis and a component wall that delimits the cooking appliance component at least in part. The component wall includes a metal substrate having an enamel coating applied thereto at least in part, and at least one surface portion free of the enamel coating so as to be electrically conductive for making electrical contact with the metal substrate. The metal substrate, at least in part, is a steel that is heat-resistant and at least one of austenitic or ferritic.

Abstract: In a method for monitoring the functionality of a temperature sensor that can deliver an electrical signal as a function of the measured temperature and is disposed, in particular, in the cooling water circuit of an internal combustion engine, the persistence of the temperature sensor in the high signal range is made possible by a method encompassing the following steps: Characterizing the sensor as possibly faulty if the sensor indicates, upon engine shutdown, at least a maximum value of the cooling fluid temperature; determining a first gradient of the cooling fluid temperature, measured by the possibly faulty sensor, up to a first point in time after engine shutdown, and characterizing the sensor as fault-free if the gradient exceeds a minimum value; determining a second gradient of the cooling fluid temperature, measured by the possibly faulty sensor, between the point in time and a point in time after engine shutdown, and characterizing the sensor as fault-free if the second gradient exceeds a minimum va

Abstract: In a method for monitoring the functionality of a temperature sensor that can deliver an electrical signal as a function of the measured temperature and is disposed, in particular, in the cooling water circuit of an internal combustion engine, the persistence of the temperature sensor in the high signal range is made possible by a method encompassing the following steps: Characterizing the sensor as possibly faulty if the sensor indicates, upon engine shutdown, at least a maximum value of the cooling fluid temperature; determining a first gradient of the cooling fluid temperature, measured by the possibly faulty sensor, up to a first point in time after engine shutdown, and characterizing the sensor as fault-free if the gradient exceeds a minimum value; determining a second gradient of the cooling fluid temperature, measured by the possibly faulty sensor, between the point in time and a point in time after engine shutdown, and characterizing the sensor as fault-free if the second gradient exceeds a minimum va

Abstract: The invention relates to a solid pharmaceutical form obtainable by melt extrusion comprising an LTB4 antagonist, which is embedded in a polymer matrix (solid dispersion).

Abstract: A solid dosage form for application in the oral cavity, comprising a poorly bioavailable pharmaceutical active ingredient dispersed in a pharmaceutically acceptable matrix.

Abstract: Solid, elongate dosage forms (10) with a long axis (11) and with a length (L) which is defined by projection of the ends (12, 13) of the dosage form to the long axis, where a cross-sectional area (14, 15, 16) oriented perpendicular to the long axis (11) has an area which is variable along the long axis (11) and increases from a cross-sectional area (15) which is located between the ends (12, 13) and has a minimal area essentially continuously toward the two ends (12, 13) up to in each case a cross-sectional area (14 and 16 respectively) with a maximal area, wherein the distance of the maximal cross-sectional area (14) which is located near one end (12) from the maximal cross-sectional area (16) which is located near the other end (13) is, projected on the long axis (11), more than half the length (L) of the dosage form (10), are described.

Abstract: A fast-acting analgesic comprises as analgesic substance ibuprofen in an adjuvant matrix with a porous structure and a density of greater than 1 and up to 2.5 g/cm3.

Abstract: The invention relates to solid drug forms obtainable by extrusion with subsequent shaping of a solvent-free melt, comprising, besides one or more active ingredients, A) 10-90% by weight of a melt-processable, water-soluble polymer, B) 5-85% by weight of isomalt, and C) 0-5% by weight of lecithin, where the total of all the ingredients is to be equal to 100% by weight.