Abstract: The invention relates to a method and a measuring device for continuously non-invasively determining at least one cardiovascular parameter, preferably the arterial blood pressure, at an extremity containing an artery, the measuring device comprising a receiving element that can be attached to the extremity and is suited to at least partly surround the extremity, and comprising a flexible bubble which is supported on the receiving element, acts on the extremity and is filled with a fluid. According to the invention, an actuator which is suited to vary the pressure in the flexible bubble is placed in or on the receiving element, and the flexible bubble includes a pressure sensor which is in contact with the fluid in the flexible bubble and which is suited to continuously measure the absolute pressure value. The measuring device further comprises a unit suited to measure the pulsations generated by the volume flow in the artery, and a control unit having two different modes of operation, i.e.

Abstract: The invention describes a measuring system for the continuous non-invasive determination of blood pressure at one or more fingers. The fingers chosen for measurement and the adjacent parts of the palm rest on a supporting surface of a housing, which has the shape of a computer mouse. Inside the housing of the “CNAP Mouse”, i.e. underneath the supporting surface for the hand, the pressure generating system is located. The finger sensors are mounted on the supporting surface for the hand. The forearm and the back of the hand are left free and may be used to place intra-venous or intra-arterial access elements. Since the hand will rest on the supporting surface motion artefacts are largely avoided. Tilting or turning of the sensors is hardly possible since the fit of the sensors and thus the coupling of light and pressure are optimized.

Abstract: The invention describes a measuring system for the continuous non-invasive determination of blood pressure at one or more fingers. The fingers chosen for measurement and the adjacent parts of the palm rest on a supporting surface of a housing, which has the shape of a computer mouse. Inside the housing of the “CNAP Mouse”, i.e. underneath the supporting surface for the hand, the pressure generating system is located. The finger sensors are mounted on the supporting surface for the hand. The forearm and the back of the hand are left free and may be used to place intra-venous or intra-arterial access elements. Since the hand will rest on the supporting surface motion artefacts are largely avoided. Tilting or turning of the sensors is hardly possible since the fit of the sensors and thus the coupling of light and pressure are optimized.

Abstract: The invention relates to a method and an apparatus for validating a continuously measuring, non-invasive blood pressure measuring system equipped with a plethysmographic system capable of obtaining—in a measuring phase—a plethysmographic signal v(t) at an extremity, having a control mechanism to which the signal v(t) from the plethysmographic system is fed, which varies the contact pressure pC(t) at the extremity via a control value u(t), and having an evaluation unit which continuously determines the arterial blood pressure curve pA(t) based on the resulting contact pressure pC(t). According to the invention, the blood pressure measuring system has a coupling interface via which—in a validation or test phase—a signal derived from a previously recorded blood pressure curve can be input into the blood pressure measuring system.

Abstract: The invention describes a measuring system for the continuous non-invasive determination of blood pressure at one or more fingers. The fingers chosen for measurement and the adjacent parts of the palm rest on a supporting surface of a housing, which has the shape of a computer mouse. Inside the housing of the “CNAP Mouse”, i.e. underneath the supporting surface for the hand, the pressure generating system is located. The finger sensors are mounted on the supporting surface for the hand. The forearm and the back of the hand are left free and may be used to place intra-venous or intra-arterial access elements. Since the hand will rest on the supporting surface motion artefacts are largely avoided. Tilting or turning of the sensors is hardly possible since the fit of the sensors and thus the coupling of light and pressure are optimized.

Abstract: A device and method for use in monitoring blood pressure. The device comprises a controller configured to monitor a first blood pressure measurement based on a first blood pressure signal. The controller is configured to initiate acquiring a second blood pressure measurement based on a second blood pressure signal if the first blood pressure measurement exceeds a predetermined threshold. The decision to initiate acquiring the second blood pressure measurement is based on only one blood pressure measurement.

Abstract: A device and method for use in monitoring blood pressure. The device comprises a controller configured to monitor a first blood pressure measurement based on a first blood pressure signal. The controller is configured to initiate acquiring a second blood pressure measurement based on a second blood pressure signal if the first blood pressure measurement exceeds a predetermined threshold. The decision to initiate acquiring the second blood pressure measurement is based on only one blood pressure measurement.

Abstract: The invention relates to methods and devices for continuous, non-invasive measurement of arterial blood pressure. One embodiment of the invention as illustrated in FIG. 1 comprises (a) a first radiation source (1) and at least one other radiation source (2); (b) at least one detector (4); (c) an air pressure generator, one or more valves, a manometer and a cuff (9, 10, 11, 12) for applying time-variable pressure on the body part, wherein a pressure signal p(t) corresponds to the arterial blood pressure; (d) a reference signal generator (6); and (e) a filter (7), which receives the reference signal and separates a supplementing signal from a favored signal.

Abstract: A device and method for use in monitoring blood pressure. The device comprises a controller configured to monitor a first blood pressure measurement based on a first blood pressure signal. The controller is configured to initiate acquiring a second blood pressure measurement based on a second blood pressure signal if the first blood pressure measurement exceeds a predetermined threshold. The decision to initiate acquiring the second blood pressure measurement is based on only one blood pressure measurement.

Abstract: A system and method of enhancing a blood pressure signal is disclosed. The volume of an artery in a finger is measured by a photo-plesthysmographic (PPG) system, which produces a PPG signal. This PPG system is placed inside a cuff, and the cuff pressure is controlled by the PPG signal. The portion or component of the PPG signal having a frequency higher than a predefined threshold frequency is then modified or enhanced, such as by multiplying the high frequency component by a calibration factor. A blood pressure signal is then calculated using the cuff pressure and the modified PPG signal. A blood pressure contour curve may then be generated, and a variety of parameters may be calculated using the curve.

Abstract: A sensor system for continuous non-invasive arterial blood pressure (CNAP) is provided. The CNAP-sensor comprises of a base portion and a detachable and disposable portion. The base portion is connected to a control system. The disposable portion is for attachment to a human body part. The CNAP-sensor system includes a photo-plethysmographic (PPG) system having at least one light source, at least one light detector, electrical supplies, light coupling systems, one or more connectors, and a cuff including air supplies.

Abstract: A device and method for use in monitoring blood pressure. The device comprises a controller configured to monitor a first blood pressure measurement based on a first blood pressure signal. The controller is configured to initiate acquiring a second blood pressure measurement based on a second blood pressure signal if the first blood pressure measurement exceeds a predetermined threshold. The decision to initiate acquiring the second blood pressure measurement is based on only one blood pressure measurement.

Abstract: A system and method of digital control for a blood pressure measurement system is provided. According to at least one embodiment, a photo-plethysmographic (PPG) system produces a frequency signal that corresponds to the measured light in the PPG system. Such light may be indicative of blood volume in a vein or artery. The frequency signal may be used to control one or more pressure valves of the system in order to measure blood pressure and hold the frequency signal constant.

Abstract: A sensor system for continuous non-invasive arterial blood pressure (CNAP) is provided. The CNAP-sensor comprises of a base portion and a detachable and disposable portion. The base portion is connected to a control system. The disposable portion is for attachment to a human body part. The CNAP-sensor system includes a photo-plethysmographic (PPG) system having at least one light source, at least one light detector, electrical supplies, light coupling systems, one or more connectors, and a cuff including air supplies.

Abstract: The invention relates to a method and a device for regulating the pressure in at least one inflatable cuff, preferably a finger cuff (6), of a blood pressure manometer comprising a plethysmographic sensor device (8, 9) for detecting a plethysmographic signal PG and a pressure sensor (7) for detecting a cuff pressure signal BP. According to the invention, two control loops (1, 2) acting on a differential amplifier (10) are used to independently regulate different operating parameters, the first, inner control loop (1) using the cuff pressure signal BP as the first regulating variable, and the second, outer control loop (2) comprising a regulating device (12), preferably a PID regulator, which generates a nominal value SW as a second regulating variable from the plethysmographic signal PG. The differential amplifier (10) is connected, on the output side, to at least one valve connected to a pressure source (4), preferably a proportional valve (3; 25, 27), for regulating the pressure in the cuff (6).

Abstract: A system and method of digital control for a blood pressure measurement system is provided. According to at least one embodiment, a photo-plethysmographic (PPG) system produces a frequency signal that corresponds to the measured light in the PPG system. Such light may be indicative of blood volume in a vein or artery. The frequency signal may be used to control one or more pressure valves of the system in order to measure blood pressure and hold the frequency signal constant.

Abstract: A system and method of enhancing a blood pressure signal is disclosed. The volume of an artery in a finger is measured by a photo-plesthysmographic (PPG) system, which produces a PPG signal. This PPG system is placed inside a cuff, and the cuff pressure is controlled by the PPG signal. The portion or component of the PPG signal having a frequency higher than a predefined threshold frequency is then modified or enhanced, such as by multiplying the high frequency component by a calibration factor. A blood pressure signal is then calculated using the cuff pressure and the modified PPG signal. A blood pressure contour curve may then be generated, and a variety of parameters may be calculated using the curve.

Abstract: A method is provided for measuring the volume, the composition and the movement of electroconductive body fluids, based on the electrical impedance of the body or a body segment, especially for performing electromechanocardiography (ELMEC) or impedance cardiography (IKG) measurements for determining hemodynamic parameters. According to the method, an alternating measuring current of at least one frequency is introduced into the body, and the impedance and temporal variations thereof of essentially the same body segment through which the alternating measuring current flows are measured for at least two different measuring lengths (L, L2, L3, L4, L5), essentially in the longitudinal direction of the body.

Abstract: The invention relates to methods and devices for continuous, non-invasive measurement of arterial blood pressure. One embodiment of the invention as illustrated in FIG. 1 comprises (a) a first radiation source (1) and at least one other radiation source (2); (b) at least one detector (4); (c) an air pressure generator, one or more valves, a manometer and a cuff (9, 10, 11, 12) for applying time-variable pressure on the body part, wherein a pressure signal p(t) corresponds to the arterial blood pressure; (d) a reference signal generator (6); and (e) a filter (7), which receives the reference signal and separates a supplementing signal from a favored signal.

Abstract: A method for the continuous non-invasive measurement of blood pressure includes at least one first pressure cuff and one second pressure cuff of comparable or identical size, each cuff including an inflatable pressure measuring chamber applicable to a first and a second body part or region containing an artery. The first pressure cuff has a first plethysmographic sensor connected to a regulating and control device used to regulate the pressure in a first pressure measuring chamber by means of a measuring signal of the plethysmographic sensor. The first pressure measuring chamber is connected to a pressure sensor in order to obtain a pressure measuring signal. The second pressure measuring chamber is a reference pressure chamber that can be regulated at the same time as the first pressure measuring chamber, independently therefrom, and can be regulated by the regulating and control device according to a pre-determinable pressure function.