Abstract: The present invention describes novel methods to generate MHC multimers and methods to improve existing and new MHC multimers. The invention also describes improved methods for the use of MHC multimers in analysis of T-cells in samples including diagnostic and prognostic methods. Furthermore, the use of MHC multimers in therapy are described, e.g. anti-tumour and anti-virus therapy, including isolation of antigen specific T-cells capable of inactivation or elimination of undesirable targeT-cells or isolation of specific T-cells capable of regulation of other immune cells.

Abstract: A wind turbine comprises a wind-driven rotor for converting wind energy to a mechanical driving force, a power converter for converting the driving force to exploitable power, and a drive train for rotatably transmitting the driving force from the wind-driven rotor to the power converter. The drive train includes: at least one rotatable driving element configured to provide at least one torsional resonance frequency in the drive train; a first detuner having at least one first mass element with a first mass inertia and at least one first elastic element with first elastic properties; and a second detuner having at least one second mass element with a second mass inertia and at least one second elastic element with second elastic properties. The first and second mass elements and first and second elastic elements are arranged to rotate during operation of the wind turbine. The torsional resonance frequency is influenced by the first and second mass inertias and the first and second first elastic properties.

Abstract: A wind turbine comprises a wind-driven rotor for converting wind energy to a mechanical driving force, a power converter for converting the driving force to exploitable power, and a drive train for rotatably transmitting the driving force from the wind-driven rotor to the power converter. The drive train includes: at least one rotatable driving element configured to provide at least one torsional resonance frequency in the drive train; a first detuner having at least one first mass element with a first mass inertia and at least one first elastic element with first elastic properties; and a second detuner having at least one second mass element with a second mass inertia and at least one second elastic element with second elastic properties. The first and second mass elements and first and second elastic elements are arranged to rotate during operation of the wind turbine. The torsional resonance frequency is influenced by the first and second mass inertias and the first and second first elastic properties.